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View Structure Prediction Details

Protein: PRM4
Organism: Saccharomyces cerevisiae
Length: 284 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PRM4.

Description E-value Query
Range
Subject
Range
PRM4 - Pheromone-regulated protein proposed to be involved in mating; predicted to have 1 transmembrane seg...
PRM4_YEAST - Pheromone-regulated membrane protein 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=P...
3.0E-67 [1..284] [1..284]
GRS17_ARATH - Monothiol glutaredoxin-S17 OS=Arabidopsis thaliana GN=GRXS17 PE=1 SV=1
9.0E-35 [50..269] [53..253]
GRS11_ORYSJ - Monothiol glutaredoxin-S11 OS=Oryza sativa subsp. japonica GN=GRXS11 PE=2 SV=2
GRS11_ORYSA - Monothiol glutaredoxin-S11 - Oryza sativa (Rice)
2.0E-34 [48..267] [50..248]
grx4 - glutaredoxin Grx4
GLRX4_SCHPO - Monothiol glutaredoxin-4 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=grx4 PE=1 SV=1
1.0E-32 [47..265] [49..242]
gi|85117048 - gi|85117048|ref|XP_965167.1| hypothetical protein NCU00974 [Neurospora crassa OR74A]
gi|32409347, gi|... - gi|38567046|emb|CAE76344.1| related to glutaredoxin [Neurospora crassa], gi|32409347|ref|XP_325154.1...
2.0E-31 [55..280] [37..252]
gi|4929735 - gi|4929735|gb|AAD34128.1|AF151891_1 CGI-133 protein [Homo sapiens]
4.0E-30 [110..277] [4..149]
gi|2724050, gi|2... - gi|2724056|gb|AAB92658.1| glutaredoxin type I [Fritillaria agrestis], gi|2724054|gb|AAB92657.1| glut...
1.0E-28 [158..272] [4..103]
gi|116310771, gi... - gi|125548975|gb|EAY94797.1| hypothetical protein OsI_16580 [Oryza sativa Indica Group], gi|116310771...
GRXC6_ORYSA, GLR... - Glutaredoxin-C6 (Glutaredoxin-C2 homolog 1) - Oryza sativa (Rice), (P55142) Glutaredoxin
GRXC6_ORYSJ - Glutaredoxin-C6 OS=Oryza sativa subsp. japonica GN=GRXC6 PE=1 SV=2
6.0E-28 [158..276] [4..107]

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Predicted Domain #1
Region A:
Residues: [1-118]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIADSSVLKK HTAIKRSTRI ISLTLVLLGV FSFLLLTWND SLEFYNSADP SENKKNSEEE  60
   61 SEKKFVYKLP NLLKTADSFL SNENELNFQK VKEEISNIQS EVEVDIPEPS SKATSKFS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.535 a.24.3 Cytochromes
View Download 0.345 a.69.3 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain
View Download 0.535 a.24.3 Cytochromes
View Download 0.488 a.24.3 Cytochromes
View Download 0.488 a.24.3 Cytochromes
View Download 0.390 a.24.3 Cytochromes
View Download 0.345 a.69.3 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain
View Download 0.321 f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region
View Download 0.321 f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region
View Download 0.303 a.46.1 Methionine synthase domain
View Download 0.303 a.63.1 Apolipophorin-III
View Download 0.301 a.24.4 Hemerythrin
View Download 0.292 a.47.2 t-snare proteins
View Download 0.290 a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.284 a.40.1 Calponin-homology domain, CH-domain
View Download 0.251 i.11.1 Computational models partly based on NMR data
View Download 0.247 a.151.1 Glutamyl tRNA-reductase dimerization domain
View Download 0.244 a.90.1 Transcription factor STAT-4 N-domain
View Download 0.242 a.2.5 Prefoldin
View Download 0.223 f.18.1 F1F0 ATP synthase subunit A
View Download 0.217 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.216 a.121.1 Tetracyclin repressor-like, C-terminal domain
View Download 0.212 a.1.1 Globin-like
View Download 0.210 a.26.1 4-helical cytokines
View Download 0.208 a.133.1 Phospholipase A2, PLA2
View Download 0.207 d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.206 a.4.5 "Winged helix" DNA-binding domain

Predicted Domain #2
Region A:
Residues: [119-284]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SRSFQTDNVV TATTTTTLNP RSSSLALQKN CDHKKFDPRT DFLDIIRTSP AVLFIKSSQA  60
   61 DSIFLKNLLQ REFEISPELA TVDLEKHSHG YELEKYIKQN KLNIDTSAAL ESIQSPYLFL 120
  121 NGISVINRGM VRDIIEPHSK GLLLPLLKSE ARGNLLVEKK DIPSNS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.154902
Match: 1jhb__
Description: Glutaredoxin (Grx, thioltransferase)
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle