YRC Public Data Repository - Protein Structure Prediction

Protein:	ATG5
Organism:	Saccharomyces cerevisiae
Length:	294 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ATG5.

Description	E-value	Query Range	Subject Range
ATG5_YEAST - Autophagy protein 5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ATG5 PE=1 SV=1 gi\|190407812 - gi\|190407812\|gb\|EDV11077.1\| autophagy protein 5 [Saccharomyces cerevisiae RM11-1a] gi\|207340633 - gi\|207340633\|gb\|EDZ68925.1\| YPL149Wp-like protein [Saccharomyces cerevisiae AWRI1631] ATG5 - Conserved protein involved in autophagy and the Cvt pathway; undergoes conjugation with Atg12p to fo...	0.0	[1..294]	[1..294]
ATG5 - ATG5 autophagy related 5 homolog (S. cerevisiae) gi\|55627156, gi\|... - gi\|55627156\|ref\|XP_518659.1\| PREDICTED: hypothetical protein LOC462905 isoform 4 [Pan troglodytes], ... gi\|109072199, gi... - gi\|109072201\|ref\|XP_001088300.1\| PREDICTED: APG5 autophagy 5-like isoform 4 [Macaca mulatta], gi\|109...	0.0	[3..283]	[6..271]
ATG5_MOUSE - Autophagy protein 5 OS=Mus musculus GN=Atg5 PE=1 SV=1	2.0E-99	[3..283]	[6..271]
Atg5-PA - The gene Autophagy-specific gene 5 is referred to in FlyBase by the symbol Dmel\Atg5 (CG1643, FBgn00... gi\|220956516, gi... - gi\|220956516\|gb\|ACL90801.1\| Atg5-PA [synthetic construct], gi\|220946960\|gb\|ACL86023.1\| Atg5-PA [synt...	1.0E-79	[3..281]	[6..264]
ATG5_SCHPO - Autophagy protein 5 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=atg5 PE=1 SV=1 mug77 - autophagy associated protein Atg5	3.0E-70	[3..284]	[9..261]
ATG5_ARATH - Autophagy protein 5 OS=Arabidopsis thaliana GN=ATG5 PE=2 SV=1	3.0E-66	[8..282]	[9..331]
CE27025 - WBGene00022152 status:Partially_confirmed TR:Q95XN4 protein_id:AAK73911.1	1.0E-51	[3..206]	[4..189]
gi\|85092056 - gi\|85092056\|ref\|XP_959205.1\| hypothetical protein [Neurospora crassa OR74A] ATG5_NEUCR - Autophagy protein 5 - Neurospora crassa	2.0E-38	[4..282]	[165..395]

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Predicted Domain #1

Region A:
Residues: [1-196]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNDIKQLLWN GELNVLVSID PSFLMKGSPR EIAVLRIRVP RETYLVNYMP LIWNKIKSFL  60
   61 SFDPLTDSEK YFWFEHNKTP IPWNYPVGVL FDCLAGKSAT FTTSFENQVK DVLTFLRIHL 120
  121 VMGDSLPPTI IPIASSKTQA EKFWFHQWKQ VCFILNGSSK AIMSLSVNEA RKFWGSVITR 180
  181 NFQDFIEISN KISSSR

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [197-294]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PRHIPLIIQT SRTSGTFRIS QPTISMTGVN PTLKDIEGDI LDVKEGINGN DVMVICQGIE  60
   61 IPWHMLLYDL YSKLRSFDGF LYITLVPIKG GDKASSEL

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits