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View Structure Prediction Details

Protein: ULP1
Organism: Saccharomyces cerevisiae
Length: 621 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ULP1.

Description E-value Query
Range
Subject
Range
ULP1_YEAST - Ubiquitin-like-specific protease 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ULP1 ...
ULP1 - Ubl (ubiquitin-like protein)-specific protease that cleaves Smt3p protein conjugates; specifically r...
0.0 [1..621] [1..621]
gi|15217714 - gi|15217714|ref|NP_174099.1| Ulp1 protease family protein [Arabidopsis thaliana]
2.0E-98 [39..618] [583..1187]
SENP2 - SUMO1/sentrin/SMT3 specific peptidase 2
5.0E-97 [66..620] [32..588]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
6.0E-96 [39..618] [583..1187]
SENP2_MOUSE - Sentrin-specific protease 2 OS=Mus musculus GN=Senp2 PE=1 SV=2
3.0E-95 [50..620] [20..587]

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Predicted Domain #1
Region A:
Residues: [1-153]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVEVDKHRN TLQYHKKNPY SPLFSPISTY RCYPRVLNNP SESRRSASFS GIYKKRTNTS  60
   61 RFNYLNDRRV LSMEESMKDG SDRASKAGFI GGIRETLWNS GKYLWHTFVK NEPRNFDGSE 120
  121 VEASGNSDVE SRSSGSRSSD VPYGLRENYS SDT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [154-263]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RKHKFDTSTW ALPNKRRRIE SEGVGTPSTS PISSLASQKS NCDSDNSITF SRDPFGWNKW  60
   61 KTSAIGSNSE NNTSDQKNSY DRRQYGTAFI RKKKVAKQNI NNTKLVSRAQ 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [264-391]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SEEVTYLRQI FNGEYKVPKI LKEERERQLK LMDMDKEKDT GLKKSIIDLT EKIKTILIEN  60
   61 NKNRLQTRNE NDDDLVFVKE KKISSLERKH KDYLNQKLKF DRSILEFEKD FKRYNEILNE 120
  121 RKKIQEDL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.905 0.009 SUMO-specific protease activity f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore

Predicted Domain #4
Region A:
Residues: [392-621]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KKKKEQLAKK KLVPELNEKD DDQVQKALAS RENTQLMNRD NIEITVRDFK TLAPRRWLND  60
   61 TIIEFFMKYI EKSTPNTVAF NSFFYTNLSE RGYQGVRRWM KRKKTQIDKL DKIFTPINLN 120
  121 QSHWALGIID LKKKTIGYVD SLSNGPNAMS FAILTDLQKY VMEESKHTIG EDFDLIHLDC 180
  181 PQQPNGYDCG IYVCMNTLYG SADAPLDFDY KDAIRMRRFI AHLILTDALK 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1309.30103
Match: 1euvA_
Description: Ulp1 protease C-terminal domain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle