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View Structure Prediction Details

Protein: TAF3
Organism: Saccharomyces cerevisiae
Length: 353 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TAF3.

Description E-value Query
Range
Subject
Range
TAF3 - TFIID subunit (47 kDa), involved in promoter binding and RNA polymerase II transcription initiation
TAF3_YEAST - Transcription initiation factor TFIID subunit 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S2...
0.0 [1..353] [1..353]
gi|32420177, gi|... - gi|32420177|ref|XP_330532.1| predicted protein [Neurospora crassa], gi|28925609|gb|EAA34630.1| conse...
gi|85111289 - gi|85111289|ref|XP_963866.1| hypothetical protein NCU03096 [Neurospora crassa OR74A]
2.0E-38 [1..107] [1..110]
taf3 - transcription factor TFIID complex subunit Taf3
TAF3_SCHPO - Transcription initiation factor TFIID subunit 3 OS=Schizosaccharomyces pombe (strain 972 / ATCC 2484...
6.0E-29 [2..80] [4..80]
gi|6692136 - gi|6692136|gb|AAF24601.1|AC007654_17 T19E23.2 [Arabidopsis thaliana]
0.004 [2..79] [58..133]

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Predicted Domain #1
Region A:
Residues: [1-152]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTNNDFYFA LLRISILQLL KAQGFDRARP SLVDVMTDLY AKFLSLLASE VSSIAQARCD  60
   61 QDDTIALQDI TLALENLGIV KPTNVLDVYD ENSELSSSRG MEKFKDWCIY STQLTDARIT 120
  121 ALPTVELLQS EEKESDPLSA IPDYLNQLLQ NK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
general RNA polymerase II transcription factor activity 8.88482968293417 bayes_pls_golite062009
DNA binding 4.24660531286828 bayes_pls_golite062009
nucleic acid binding 4.14026521609645 bayes_pls_golite062009
lysine N-acetyltransferase activity 3.94678088447927 bayes_pls_golite062009
histone acetyltransferase activity 3.94678088447927 bayes_pls_golite062009
transcription regulator activity 3.91807454227165 bayes_pls_golite062009
transcription initiation factor activity 3.78067108255869 bayes_pls_golite062009
binding 3.14832737946099 bayes_pls_golite062009
RNA polymerase II transcription factor activity 3.02428691626433 bayes_pls_golite062009
N-acetyltransferase activity 2.46003121267868 bayes_pls_golite062009
transcription factor activity 2.39322722597434 bayes_pls_golite062009
N-acyltransferase activity 2.22658570487778 bayes_pls_golite062009
acetyltransferase activity 1.87240886310988 bayes_pls_golite062009
transcription activator activity 1.12739348005764 bayes_pls_golite062009
nucleotidyltransferase activity 1.03060091158028 bayes_pls_golite062009
protein binding 1.01897642648285 bayes_pls_golite062009
transcription factor binding 1.01773884290535 bayes_pls_golite062009
transcription coactivator activity 0.976797801726735 bayes_pls_golite062009
transcription cofactor activity 0.840442755533537 bayes_pls_golite062009
transcription repressor activity 0.621482805601238 bayes_pls_golite062009
histone binding 0.184823910505751 bayes_pls_golite062009
acyltransferase activity 0.133449022804582 bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups 0.131532799941764 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.0919482386963733 bayes_pls_golite062009
sequence-specific DNA binding 0.0585868733603467 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [153-353]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GAKQKLETKN RKTELIEDLI NNNGLDDWIK LVIARQRINM IERASKKESQ NVPALPHIAG  60
   61 YKSSILSRHH HTTITNEDRM PSAMTPRDED ALTEIQENPF VTSKLPIMRK ENRLENITLS 120
  121 FEDEELESLG EVEGPNQKSQ ENNNEESFKE NNKSLTESPH GDDRDISMFQ FDSNVDTKWA 180
  181 EQEDMDSTFQ RRTSLDYGGY F

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle