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View Structure Prediction Details

Protein: RDR1
Organism: Saccharomyces cerevisiae
Length: 546 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RDR1.

Description E-value Query
Range
Subject
Range
gi|207340805 - gi|207340805|gb|EDZ69043.1| YOR380Wp-like protein [Saccharomyces cerevisiae AWRI1631]
RDR1 - Transcriptional repressor involved in the control of multidrug resistance; negatively regulates expr...
gi|190407669 - gi|190407669|gb|EDV10936.1| protein RDR1 [Saccharomyces cerevisiae RM11-1a]
RDR1_YEAST - Protein RDR1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RDR1 PE=3 SV=1
8.0E-84 [1..546] [1..546]
SPBC1683.13c - transcription factor
YHDD_SCHPO - Uncharacterized transcriptional regulatory protein C1683.13c OS=Schizosaccharomyces pombe (strain 97...
6.0E-66 [7..531] [5..533]
NIT4_NEUCR - Nitrogen assimilation transcription factor nit-4 OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1...
NIT4_NEUCR - Nitrogen assimilation transcription factor nit-4 OS=Neurospora crassa GN=nit-4 PE=4 SV=2
4.0E-62 [2..531] [35..604]
gi|6901427 - gi|6901427|emb|CAB71797.1| pathway-specific nitrogen regulator [Tolypocladium inflatum]
7.0E-61 [5..531] [55..620]
NIRA_EMENI - Nitrogen assimilation transcription factor nirA OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 ...
NIRA_EMENI - Nitrogen assimilation transcription factor nirA OS=Emericella nidulans GN=nirA PE=4 SV=1
1.0E-57 [3..531] [25..583]
gi|21913144 - gi|21913144|gb|AAK84946.1| transcriptional activator Mut3p [Pichia angusta]
gi|134147412 - gi|134147412|gb|ABO63963.1| transcriptional activator Mut3p [synthetic construct]
5.0E-55 [2..527] [55..649]

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Predicted Domain #1
Region A:
Residues: [1-99]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASPGSTALP HKRQRVRKAC VPCRERKRKC NGKSPCEMCV AYGYVCHYID GRVPSASPQV  60
   61 QQVGETSPDT ESRPFVLPGI HRNEQPQPIN TQNVTSQNI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 36.0
Match: 1zmeC_
Description: PUT3
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.36540182658818 bayes_pls_golite062009
nucleic acid binding 1.82012686871762 bayes_pls_golite062009
DNA binding 1.78629392205727 bayes_pls_golite062009
transcription regulator activity 1.70162817919532 bayes_pls_golite062009
transcription factor activity 0.606922041618269 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.160255273911114 bayes_pls_golite062009
sequence-specific DNA binding 0.0882387940255902 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [100-546]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VDPTKSRYTI QHSAVAFPRC LGLELRSTNP PRLHSFAWHC GIRPEENPNS HVLLSDLVTK  60
   61 EEYYRISKVY FSVVHPIFDV VNPEQLAKNV EKYWDGDVKT LEYGAVIAGV IALGSFFMGS 120
  121 LGHPREMDIV QYAKGILDDP TFSRIPTVEQ VSAWVLRTIY LRATSRPHVA WLASCVTIHL 180
  181 SEAIGLHHEI DREDIAISNN VPPKRTTVVS EHTRRLFWCA WSINTILSYD YGRSSVTLNR 240
  241 ITCKPVKETD GNFTAHLVAL AHLIPQDSVN ANAAQLLQAL AAVHESPNAH PFLSLTKGDI 300
  301 CLSLYRRLRL LNHILDKNVV LQIIDIGNTA LSAAYALVKL DQAWWNVLST SFQYVCVLLA 360
  361 IDTPESLSHV ATAMKTLDNI TQILGTRIAF EAQKTAKLLL EDSMKKKRQE IQQLEQATHQ 420
  421 RSNLETTHLL DIDWDALLDP SDTLNFM

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [223-351]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PREMDIVQYA KGILDDPTFS RIPTVEQVSA WVLRTIYLRA TSRPHVAWLA SCVTIHLSEA  60
   61 IGLHHEIDRE DIAISNNVPP KRTTVVSEHT RRLFWCAWSI NTILSYDYGR SSVTLNRITC 120
  121 KPVKETDGN

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 19.568636
Match: PF04082.9
Description: No description for PF04082.9 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [352-546]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FTAHLVALAH LIPQDSVNAN AAQLLQALAA VHESPNAHPF LSLTKGDICL SLYRRLRLLN  60
   61 HILDKNVVLQ IIDIGNTALS AAYALVKLDQ AWWNVLSTSF QYVCVLLAID TPESLSHVAT 120
  121 AMKTLDNITQ ILGTRIAFEA QKTAKLLLED SMKKKRQEIQ QLEQATHQRS NLETTHLLDI 180
  181 DWDALLDPSD TLNFM

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle