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View Structure Prediction Details

Protein: PRT1
Organism: Saccharomyces cerevisiae
Length: 763 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PRT1.

Description E-value Query
Range
Subject
Range
PRT1 - eIF3b subunit of the core complex of translation initiation factor 3 (eIF3), essential for translati...
EIF3B_YEAST - Eukaryotic translation initiation factor 3 subunit B OS=Saccharomyces cerevisiae (strain ATCC 204508...
0.0 [1..763] [1..763]
EIF3B - eukaryotic translation initiation factor 3, subunit B
0.0 [39..762] [147..808]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [39..762] [147..808]
gi|186464325, gi... - gi|23128981|ref|ZP_00110817.1| COG2319: FOG: WD40 repeat [Nostoc punctiforme PCC 73102], gi|18668187...
0.0 [105..742] [1194..1751]
gi|29835226, gi|... - gi|29835226|gb|AAH51065.1| Eif3b protein [Mus musculus], gi|23271707|gb|AAH23767.1| Eif3b protein [M...
0.0 [39..756] [136..789]
EIF3B_ARATH - Eukaryotic translation initiation factor 3 subunit B OS=Arabidopsis thaliana GN=TIF3B1 PE=1 SV=1
0.0 [24..763] [5..710]
YY46_NOSS1 - Uncharacterized WD repeat-containing protein alr3466 OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=...
gi|25530855 - pir||AC2239 WD-40 repeat protein [imported] - Nostoc sp. (strain PCC 7120)
0.0 [103..679] [914..1479]

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Predicted Domain #1
Region A:
Residues: [1-160]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKNFLPRTLK NIYELYFNNI SVHSIVSRNT QLKRSKIIQM TTETFEDIKL EDIPVDDIDF  60
   61 SDLEEQYKVT EEFNFDQYIV VNGAPVIPSA KVPVLKKALT SLFSKAGKVV NMEFPIDEAT 120
  121 GKTKGFLFVE CGSMNDAKKI IKSFHGKRLD LKHRLFLYTM 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.69897
Match: 1po6A
Description: Crystal Structure of UP1 Complexed With d(TAGG(6MI)TTAGGG): A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6MI)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 4.50438526063124 bayes_pls_golite062009
translation initiation factor activity 3.27900316559423 bayes_pls_golite062009
nucleic acid binding 3.03004688154589 bayes_pls_golite062009
mRNA binding 2.92795844574986 bayes_pls_golite062009
binding 2.80563734517858 bayes_pls_golite062009
structural molecule activity 2.78501986457503 bayes_pls_golite062009
1.49431666307335 bayes_pls_golite062009
protein binding 1.02232785292059 bayes_pls_golite062009
single-stranded RNA binding 0.90573796517364 bayes_pls_golite062009
RNA cap binding 0.847034036194541 bayes_pls_golite062009
translation regulator activity 0.38120065819101 bayes_pls_golite062009
poly-pyrimidine tract binding 0.32812362201346 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.128616879457381 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [161-679]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KDVERYNSDD FDTEFREPDM PTFVPSSSLK SWLMDDKVRD QFVLQDDVKT SVFWNSMFNE  60
   61 EDSLVESREN WSTNYVRFSP KGTYLFSYHQ QGVTAWGGPN FDRLRRFYHP DVRNSSVSPN 120
  121 EKYLVTFSTE PIIVEEDNEF SPFTKKNEGH QLCIWDIASG LLMATFPVIK SPYLKWPLVR 180
  181 WSYNDKYCAR MVGDSLIVHD ATKNFMPLEA KALKPSGIRD FSFAPEGVKL QPFRNGDEPS 240
  241 VLLAYWTPET NNSACTATIA EVPRGRVLKT VNLVQVSNVT LHWQNQAEFL CFNVERHTKS 300
  301 GKTQFSNLQI CRLTERDIPV EKVELKDSVF EFGWEPHGNR FVTISVHEVA DMNYAIPANT 360
  361 IRFYAPETKE KTDVIKRWSL VKEIPKTFAN TVSWSPAGRF VVVGALVGPN MRRSDLQFYD 420
  421 MDYPGEKNIN DNNDVSASLK DVAHPTYSAA TNITWDPSGR YVTAWSSSLK HKVEHGYKIF 480
  481 NIAGNLVKED IIAGFKNFAW RPRPASILSN AERKKVRKN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 37.522879
Match: 1nr0A
Description: Actin interacting protein 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
structural molecule activity 2.6914565031145 bayes_pls_golite062009
translation initiation factor activity 2.29806492548141 bayes_pls_golite062009
binding 1.58733371663063 bayes_pls_golite062009
RNA binding 1.54614730254863 bayes_pls_golite062009
1.53488375271101 bayes_pls_golite062009
protein binding 1.11897341394404 bayes_pls_golite062009
snoRNA binding 0.503568445551651 bayes_pls_golite062009
nucleic acid binding 0.417970425588631 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [680-763]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LREWSAQFEE QDAMEADTAM RDLILHQREL LKQWTEYREK IGQEMEKSMN FKIFDVQPED  60
   61 ASDDFTTIEE IVEEVLEETK EKVE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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Created and Maintained by: Michael Riffle