YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: HAP5
Organism: Saccharomyces cerevisiae
Length: 242 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HAP5.

Description E-value Query
Range
Subject
Range
HAP5 - Subunit of the heme-activated, glucose-repressed Hap2/3/4/5 CCAAT-binding complex, a transcriptional...
gi|190407651 - gi|190407651|gb|EDV10918.1| CCAAT-binding transcription factor component [Saccharomyces cerevisiae R...
gi|207340830 - gi|207340830|gb|EDZ69060.1| YOR358Wp-like protein [Saccharomyces cerevisiae AWRI1631]
HAP5_YEAST - Transcriptional activator HAP5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HAP5 PE=1...
gi|151945435 - gi|151945435|gb|EDN63678.1| CCAAT-binding transcription factor component (along with Hap2p and Hap3p...
1.0E-54 [1..242] [1..242]
gi|447739 - gi|447739|prf||1915304A nylB upstream ORF
6.0E-45 [27..242] [1..216]
gi|2583171 - gi|2583171|gb|AAC15237.1| CCAAT-binding transcription factor subunit AAB-1 [Neurospora crassa]
3.0E-36 [66..239] [1..167]
H2A4_VOLCA - Histone H2A-IV OS=Volvox carteri PE=3 SV=1
3.0E-34 [136..235] [1..100]
gi|32967225 - gi|32967225|gb|AAP92405.1| HapE [Aspergillus niger]
4.0E-34 [69..239] [1..166]
gi|7023238, gi|8... - gi|8922758|ref|NP_060737.1| H2A histone family, member J isoform 1 [Homo sapiens], gi|7023238|dbj|BA...
7.0E-34 [138..235] [4..101]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
1.0E-33 [141..235] [14..108]
gi|14577940 - gi|14577940|gb|AAK68863.1| CCAAT-binding protein subunit HAP5 [Hypocrea jecorina]
1.0E-33 [66..239] [1..167]
H2A_CHLRE - Histone H2A OS=Chlamydomonas reinhardtii GN=H2A-II PE=3 SV=1
2.0E-33 [136..235] [1..100]

Back

Predicted Domain #1
Region A:
Residues: [1-142]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTDRNFSPQQ GQGPQESLPE GPQPSTMIQR EEMNMPRQYS EQQQLQENEG EGENTRLPVS  60
   61 EEEFRMVQEL QAIQAGHDQA NLPPSGRGSL EGEDNGNSDG ADGEMDEDDE EYDVFRNVGQ 120
  121 GLVGHYKEIM IRYWQELINE IE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [143-242]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STNEPGSEHQ DDFKSHSLPF ARIRKVMKTD EDVKMISAEA PIIFAKACEI FITELTMRAW  60
   61 CVAERNKRRT LQKADIAEAL QKSDMFDFLI DVVPRRPLPQ 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 311.67837
Match: 1n1jB_
Description: Nuclear transcription factor Y subunit gamma (Nf-Yc2)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
DNA binding 4.24625687315724 bayes_pls_golite062009
transcription regulator activity 4.08606081850613 bayes_pls_golite062009
nucleic acid binding 3.93473976418251 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 3.89663803383145 bayes_pls_golite062009
binding 3.84636641231951 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.38228606466152 bayes_pls_golite062009
transcription factor activity 2.31114764804139 bayes_pls_golite062009
transcription activator activity 1.25487495162413 bayes_pls_golite062009
transcription factor binding 1.15204005455906 bayes_pls_golite062009
transcription coactivator activity 1.1297723528047 bayes_pls_golite062009
transcription cofactor activity 1.01502031330902 bayes_pls_golite062009
protein binding 0.978906971260821 bayes_pls_golite062009
transcription repressor activity 0.72554769377984 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle