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View Structure Prediction Details

Protein: YOR338W
Organism: Saccharomyces cerevisiae
Length: 363 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YOR338W.

Description E-value Query
Range
Subject
Range
gi|207340855 - gi|207340855|gb|EDZ69077.1| YOR338Wp-like protein [Saccharomyces cerevisiae AWRI1631]
gi|190407633 - gi|190407633|gb|EDV10900.1| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a]
YO338_YEAST - SWIRM domain-containing protein YOR338W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=...
YOR338W - Putative protein of unknown function; YOR338W transcription is regulated by Azf1p and its transcript...
0.0 [1..363] [1..363]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
1.0E-84 [4..322] [50..422]
gi|162457760, gi... - gi|18642468|emb|CAD22882.1| transcriptional adaptor [Zea mays], gi|162457760|ref|NP_001105146.1| tra...
6.0E-61 [103..351] [310..555]
gi|32417148, gi|... - gi|38636425|emb|CAE81961.1| conserved hypothetical protein [Neurospora crassa], gi|32417148|ref|XP_3...
gi|85118725 - gi|85118725|ref|XP_965493.1| hypothetical protein [Neurospora crassa OR74A]
1.0E-59 [71..363] [134..402]
gi|18101632 - gi|18101632|gb|AAL14200.2| transcriptional adaptor-like protein [Hypocrea jecorina]
1.0E-52 [104..354] [232..511]
gi|186509898, gi... - gi|6466957|gb|AAF13092.1|AC009176_19 unknown protein [Arabidopsis thaliana], gi|186509898|ref|NP_001...
4.0E-52 [100..352] [280..522]
gi|27263225 - gi|27263225|gb|AAN88029.1| ADA2A-1 [Drosophila melanogaster]
8.0E-52 [88..354] [275..535]

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Predicted Domain #1
Region A:
Residues: [1-96]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLDNMQFHSP APEHPQLNGG INKIPASHKI GYKLNQQVQR LAVVRNNIEE RLNSMESSHG  60
   61 QISDSSVVRA IDASIDDFLI PSPPLSPKLR QCPIIS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.640 N/A N/A a.39.1 EF-hand
View Download 0.640 N/A N/A a.39.1 EF-hand
View Download 0.622 N/A N/A a.59.1 PAH2 domain
View Download 0.622 N/A N/A a.59.1 PAH2 domain
View Download 0.560 N/A N/A a.13.1 alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
View Download 0.560 N/A N/A a.13.1 alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
View Download 0.494 N/A N/A a.24.7 FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
View Download 0.494 N/A N/A a.24.7 FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
View Download 0.486 N/A N/A a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.486 N/A N/A a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.452 N/A N/A a.5.6 Hypothetical protein MTH1615
View Download 0.420 N/A N/A d.58.49 YajQ-like
View Download 0.392 N/A N/A a.2.11 Fe,Mn superoxide dismutase (SOD), N-terminal domain
View Download 0.375 N/A N/A a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.374 N/A N/A a.29.2 Bromodomain
View Download 0.343 N/A N/A f.17.1 F1F0 ATP synthase subunit C
View Download 0.342 N/A N/A a.47.2 t-snare proteins
View Download 0.324 N/A N/A d.58.4 Dimeric alpha+beta barrel
View Download 0.311 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.310 N/A N/A d.55.1 Ribosomal protein L22
View Download 0.301 N/A N/A a.25.1 Ferritin-like
View Download 0.300 N/A N/A d.150.1 4'-phosphopantetheinyl transferase
View Download 0.289 N/A N/A d.58.20 NAD-binding domain of HMG-CoA reductase
View Download 0.288 N/A N/A f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region
View Download 0.283 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.282 N/A N/A a.60.5 Barrier-to-autointegration factor, BAF
View Download 0.279 N/A N/A a.44.1 Disulphide-bond formation facilitator (DSBA), insertion domain
View Download 0.274 N/A N/A a.47.2 t-snare proteins
View Download 0.258 N/A N/A a.2.7 tRNA-binding arm
View Download 0.254 N/A N/A a.24.4 Hemerythrin
View Download 0.251 N/A N/A a.24.17 Group V grass pollen allergen
View Download 0.248 N/A N/A d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.241 N/A N/A a.24.3 Cytochromes
View Download 0.237 N/A N/A d.43.1 Elongation factor Ts (EF-Ts), dimerisation domain
View Download 0.237 N/A N/A a.7.1 Spectrin repeat
View Download 0.235 N/A N/A a.7.6 Ribosomal protein S20
View Download 0.232 N/A N/A a.8.1 Bacterial immunoglobulin/albumin-binding domains
View Download 0.228 N/A N/A a.22.1 Histone-fold
View Download 0.228 N/A N/A a.74.1 Cyclin-like
View Download 0.225 N/A N/A d.50.3 PI-Pfui intein middle domain
View Download 0.221 N/A N/A a.7.5 Tubulin chaperone cofactor A
View Download 0.215 N/A N/A a.121.1 Tetracyclin repressor-like, C-terminal domain
View Download 0.213 N/A N/A c.47.1 Thioredoxin-like
View Download 0.212 N/A N/A a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.210 N/A N/A a.130.1 Chorismate mutase II
View Download 0.208 N/A N/A a.47.2 t-snare proteins
View Download 0.205 N/A N/A d.67.3 Ribosome recycling factor, RRF

Predicted Domain #2
Region A:
Residues: [97-363]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QPQLVNVESD HRELIMLTPV WEAGLNSQKY NHNTRNFLSQ YSFFRDMKTT KRIPNKENRK  60
   61 LKVVKSVVNS EALPKRRRYD RKIKRRSREL YEDDGNRSEN YDEESAQEVP VRSVTPIRQV 120
  121 KRSLHTISSP LASQGVVNNV PKYIPSMSWE KLPDYSPPLH TLPNSNNKVL KVEWKGSPMD 180
  181 LNHDPLKQRL HPAELVLAQI LRLPCDLYLD SKRRFFLEKV HRFKKGLPFR RTDAQKACRI 240
  241 DVNKASRLFA AFEKVGWLQD KHFEKYL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [250-363]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DYSPPLHTLP NSNNKVLKVE WKGSPMDLNH DPLKQRLHPA ELVLAQILRL PCDLYLDSKR  60
   61 RFFLEKVHRF KKGLPFRRTD AQKACRIDVN KASRLFAAFE KVGWLQDKHF EKYL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.0
Match: 2cujA
Description: Solution structure of SWIRM domain of mouse transcriptional adaptor 2-like
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 3.61657063316558 bayes_pls_golite062009
DNA binding 3.20600447901865 bayes_pls_golite062009
nucleic acid binding 3.13775670276163 bayes_pls_golite062009
transcription factor activity 2.61318050866004 bayes_pls_golite062009
sequence-specific DNA binding 2.14408928200987 bayes_pls_golite062009
binding 2.12643314274039 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.77209608685482 bayes_pls_golite062009
transcription activator activity 1.75864690109096 bayes_pls_golite062009
protein binding 1.62529996900514 bayes_pls_golite062009
transcription repressor activity 0.605733396003465 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.380372494934551 bayes_pls_golite062009
chromatin binding 0.346262410069781 bayes_pls_golite062009
transcription factor binding 0.109547968922689 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle