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View Structure Prediction Details

Protein: MYO2
Organism: Saccharomyces cerevisiae
Length: 1574 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MYO2.

Description E-value Query
Range		 Subject
Range
gi|37535568, gi|... - gi|37535568|ref|NP_922086.1| putative myosin [Oryza sativa (japonica cultivar-group)], gb|AAP54373.1...
 0.0 [4..1093] [147..1170]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 0.0 [5..1542] [9..1515]
MYH4_PIG - Myosin-4 OS=Sus scrofa GN=MYH4 PE=2 SV=1
 0.0 [2..1303] [31..1358]
gi|26337045 - gi|26337045|dbj|BAC32206.1| unnamed protein product [Mus musculus]
 0.0 [3..879] [30..884]
gi|22121649 - gi|22121649|gb|AAM88909.1| fast myosin heavy chain HCII [Gallus gallus]
 0.0 [2..1327] [32..1375]
gi|4505301, gi|1... - gi|4505301|ref|NP_002463.1| myosin, heavy polypeptide 8, skeletal muscle, perinatal [Homo sapiens], ...
 0.0 [2..1327] [33..1370]
Mhc-PJ - The gene Myosin heavy chain is referred to in FlyBase by the symbol Dmel\Mhc (CG17927, FBgn0086783)....
 0.0 [2..1364] [31..1406]
gi|9944237 - gi|9944237|emb|CAC05419.1| myosin VIIA [Danio rerio]
 0.0 [6..1205] [7..1157]

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Predicted Domain #1
Region A:
Residues: [1-63] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFEVGTRCW YPHKELGWIG AEVIKNEFND GKYHLELQLE DDEIVSVDTK DLNNDKDQSL  60
   61 PLL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 2630.0
Match: 1jwyA_
Description: Myosin S1 fragment, N-terminal domain; Myosin S1, motor domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [64-342] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RNPPILEATE DLTSLSYLNE PAVLHAIKQR YSQLNIYTYS GIVLIATNPF DRVDQLYTQD  60
   61 MIQAYAGKRR GELEPHLFAI AEEAYRLMKN DKQNQTIVVS GESGAGKTVS AKYIMRYFAS 120
  121 VEEENSATVQ HQVEMSETEQ KILATNPIME AFGNAKTTRN DNSSRFGKYL EILFDKDTSI 180
  181 IGARIRTYLL ERSRLVYQPP IERNYHIFYQ LMAGLPAQTK EELHLTDASD YFYMNQGGDT 240
  241 KINGIDDAKE YKITVDALTL VGITKETQHQ IFKILAALL

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [417-452] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SALFDWLVEN INTVLCNPAV NDQISSFIGV LDIYGF

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [653-697] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ELMNTINSTN VHYIRCIKPN ADKEAWQFDN LMVLSQLRAC GVLET

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 2630.0
Match: 1jwyA_
Description: Myosin S1 fragment, N-terminal domain; Myosin S1, motor domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [343-416] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HIGNIEIKKT RNDASLSADE PNLKLACELL GIDAYNFAKW VTKKQIITRS EKIVSNLNYS  60
   61 QALVAKDSVA KFIY

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [453-483] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EHFEKNSFEQ FCINYANEKL QQEFNQHVFK L

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [498-652] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IEFNDNQPCI DLIENKLGIL SLLDEESRLP AGSDESWTQK LYQTLDKSPT NKVFSKPRFG  60
   61 QTKFIVSHYA LDVAYDVEGF IEKNRDTVSD GHLEVLKAST NETLINILEG LEKAAKKLEE 120
  121 AKKLELEQAG SKKPGPIRTV NRKPTLGSMF KQSLI

[Run NCBI BLAST on this sequence.]

Region D:
Residues: [698-701] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IRIS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 2630.0
Match: 1jwyA_
Description: Myosin S1 fragment, N-terminal domain; Myosin S1, motor domain
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [484-497] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EQEEYVKEEI EWSF

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [702-783] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CAGFPSRWTF EEFVLRYYIL IPHEQWDLIF KKKETTEEDI ISVVKMILDA TVKDKSKYQI  60
   61 GNTKIFFKAG MLAYLEKLRS NK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 2630.0
Match: 1jwyA_
Description: Myosin S1 fragment, N-terminal domain; Myosin S1, motor domain
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [784-844] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHNSIVMIQK KIRAKYYRKQ YLQISQAIKY LQNNIKGFII RQRVNDEMKV NCATLLQAAY  60
   61 R

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.522879
Match: 1wdcA_
Description: SCALLOP MYOSIN REGULATORY DOMAIN
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [845-1009] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GHSIRANVFS VLRTITNLQK KIRKELKQRQ LKQEHEYNAA VTIQSKVRTF EPRSRFLRTK  60
   61 KDTVVVQSLI RRRAAQRKLK QLKADAKSVN HLKEVSYKLE NKVIELTQNL ASKVKENKEM 120
  121 TERIKELQVQ VEESAKLQET LENMKKEHLI DIDNQKSKDM ELQKT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.0
Match: 1cii__
Description: Colicin Ia; Colicin Ia, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #7
Region A:
Residues: [1010-1327] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IENNLQSTEQ TLKDAQLELE DMVKQHDELK EESKKQLEEL EQTKKTLVEY QTLNGDLQNE  60
   61 VKSLKEEIAR LQTAMSLGTV TTSVLPQTPL KDVMGGGASN FNNMMLENSD LSPNDLNLKS 120
  121 RSTPSSGNNH IDSLSVDREN GVNATQINEE LYRLLEDTEI LNQEITEGLL KGFEVPDAGV 180
  181 AIQLSKRDVV YPARILIIVL SEMWRFGLTK QSESFLAQVL TTIQKVVTQL KGNDLIPSGV 240
  241 FWLANVRELY SFVVFALNSI LTEETFKNGM TDEEYKEYVS LVTELKDDFE ALSYNIYNIW 300
  301 LKKLQKQLQK KAINAVVI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.0
Match: 1cii__
Description: Colicin Ia; Colicin Ia, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #8
Region A:
Residues: [1328-1380] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SESLPGFSAG ETSGFLNKIF ANTEEYTMDD ILTFFNSIYW CMKSFHIENE VFH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #9
Region A:
Residues: [1381-1509] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AVVTTLLNYV DAICFNELIM KRNFLSWKRG LQLNYNVTRL EEWCKTHGLT DGTECLQHLI  60
   61 QTAKLLQVRK YTIEDIDILR GICYSLTPAQ LQKLISQYQV ADYESPIPQE ILRYVADIVK 120
  121 KEAALSSSG

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 46.657577
Match: PF01843
Description: DIL domain

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #10
Region A:
Residues: [1510-1574] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NDSKGHEHSS SIFITPETGP FTDPFSLIKT RKFDQVEAYI PAWLSLPSTK RIVDLVAQQV  60
   61 VQDGH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score		 GO
Score		 GO
Term		 SCOP
Match		 SCOP Description
View Download 0.681 0.945 microfilament motor activity a.39.1 EF-hand

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle