YRC Public Data Repository - Protein Structure Prediction

Protein:	NAT5
Organism:	Saccharomyces cerevisiae
Length:	176 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NAT5.

Description	E-value	Query Range	Subject Range
gi\|18976639, gi\|... - gi\|18976639\|ref\|NP_577996.1\| ribosomal protein s18 alanine acetyltransferase [Pyrococcus furiosus DS...	1.0E-29	[5..174]	[17..160]
gi\|14521872, gi\|... - gi\|5459092\|emb\|CAB50578.1\| N-terminal acetyltransferase [Pyrococcus abyssi GE5], gi\|14521872\|ref\|NP_... gi\|5459092, gi\|7... - pir\|\|D75017 n-terminal acetyltransferase PAB1098 - Pyrococcus abyssi (strain Orsay), gi\|5459092\|emb...	4.0E-29	[6..173]	[20..161]
gi\|18312168, gi\|... - gi\|18312168\|ref\|NP_558835.1\| N-acyltransferase [Pyrobaculum aerophilum str. IM2], gi\|18159603\|gb\|AAL...	3.0E-28	[2..175]	[18..176]
gi\|14590218, gi\|... - gi\|3256685\|dbj\|BAA29368.1\| 172aa long hypothetical acetyltransferase [Pyrococcus horikoshii OT3], gi... gi\|7451125 - pir\|\|A71455 probable acetyltransferase - Pyrococcus horikoshii	4.0E-28	[6..173]	[20..161]
gi\|25394674 - pir\|\|C90162 acetyltransferase, probable [imported] - Sulfolobus solfataricus gi\|15897159, gi\|... - gi\|15897159\|ref\|NP_341764.1\| acetyltransferase [Sulfolobus solfataricus P2], gi\|13813346\|gb\|AAK40554...	4.0E-27	[2..175]	[58..216]
Y258_SULTO - Uncharacterized N-acetyltransferase ST0258 OS=Sulfolobus tokodaii GN=ST0258 PE=3 SV=1 Y258_SULTO - Uncharacterized N-acetyltransferase STK_02580 OS=Sulfolobus tokodaii (strain DSM 16993 / JCM 10545 /...	5.0E-27	[7..175]	[13..167]
gi\|162459719, gi... - gi\|162459719\|ref\|NP_001105068.1\| silencing group B protein [Zea mays], gi\|14550116\|gb\|AAK67148.1\|AF3...	2.0E-26	[5..175]	[1..152]
gi\|1742360, gi\|1... - dbj\|BAA15083.1\| Phosphinothricin acetyltransferase (EC 2.3.1.-). [Escherichia coli], dbj\|BAA15080.1...	3.0E-26	[3..175]	[38..202]
Y1207_METJA, YC0... - (Q58604) Hypothetical acetyltransferase MJ1207 (EC 2.3.1.-), Uncharacterized N-acetyltransferase MJ1... Y1207_METJA - Uncharacterized N-acetyltransferase MJ1207 OS=Methanocaldococcus jannaschii (strain ATCC 43067 / DSM...	7.0E-26	[7..149]	[76..212]
NAA20 - N(alpha)-acetyltransferase 20, NatB catalytic subunit gi\|114681197 - gi\|114681197\|ref\|XP_514540.2\| PREDICTED: similar to Nat5-prov protein isoform 2 [Pan troglodytes] gi\|149733391 - gi\|149733391\|ref\|XP_001489957.1\| PREDICTED: similar to Nat5-prov protein [Equus caballus] gi\|109470944, gi... - ref\|XP_342535.1\| similar to N-acetyltransferase 5 [Rattus norvegicus], gi\|149041205\|gb\|EDL95138.1\| ... NAA20_MACFA - N-alpha-acetyltransferase 20 OS=Macaca fascicularis GN=NAA20 PE=2 SV=1 NAA20_MOUSE - N-alpha-acetyltransferase 20 OS=Mus musculus GN=Naa20 PE=1 SV=1 gi\|123998053, gi... - gi\|61361621\|gb\|AAX42077.1\| N-acetyltransferase 5 [synthetic construct], gi\|123998111\|gb\|ABM86657.1\| ...	8.0E-26	[5..176]	[1..157]

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Predicted Domain #1

Region A:
Residues: [1-176]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGRDICTLDN VYANNLGMLT KLAHVTVPNL YQDAFFSALF AEDSLVAKNK KPSSKKDVHF  60
   61 TQMAYYSEIP VGGLVAKLVP KKQNELSLKG IQIEFLGVLP NYRHKSIGSK LLKFAEDKCS 120
  121 ECHQHNVFVY LPAVDDLTKQ WFIAHGFEQV GETVNNFIKG VNGDEQDAIL LKKHIS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	14.69897
Match:	1bo4A_
Description:	Aminoglycoside 3-N-acetyltransferase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
N-acetyltransferase activity	6.19030807112666	bayes_pls_golite062009
N-acyltransferase activity	6.08913516066746	bayes_pls_golite062009
histone acetyltransferase activity	6.0067454358666	bayes_pls_golite062009
lysine N-acetyltransferase activity	6.0067454358666	bayes_pls_golite062009
acetyltransferase activity	5.86411968036951	bayes_pls_golite062009
acyltransferase activity	4.72881921515185	bayes_pls_golite062009
transferase activity, transferring acyl groups	4.70793039001114	bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups	4.69837915971204	bayes_pls_golite062009
transferase activity	3.5778020729894	bayes_pls_golite062009
glycylpeptide N-tetradecanoyltransferase activity	3.50779447340192	bayes_pls_golite062009
myristoyltransferase activity	3.50779447340192	bayes_pls_golite062009
	3.29707445389818	bayes_pls_golite062009
catalytic activity	1.97933499002461	bayes_pls_golite062009
binding	0.203201636645541	bayes_pls_golite062009
protein binding	0.0596470189462109	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: