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View Structure Prediction Details

Protein: MGM1
Organism: Saccharomyces cerevisiae
Length: 902 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MGM1.

Description E-value Query
Range
Subject
Range
MGM1 - Mitochondrial GTPase related to dynamin, present in a complex containing Ugo1p and Fzo1p; required f...
0.0 [1..902] [1..902]
MSP1_SCHPO - Protein msp1, mitochondrial OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=msp1 PE=3 SV=2
msp1 - mitochondrial GTPase Msp1
0.0 [80..896] [72..901]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [80..896] [72..901]
gi|119598474, gi... - gi|18860833|ref|NP_570845.1| optic atrophy 1 isoform 3 [Homo sapiens], gi|119598474|gb|EAW78068.1| o...
0.0 [4..883] [8..939]
OPA1_MOUSE - Dynamin-like 120 kDa protein, mitochondrial OS=Mus musculus GN=Opa1 PE=1 SV=1
0.0 [4..883] [8..957]

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Predicted Domain #1
Region A:
Residues: [1-184]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNSTSLRAI PRVANYNTLV RMNASPVRLL ILRRQLATHP AILYSSPYIK SPLVHLHSRM  60
   61 SNVHRSAHAN ALSFVITRRS ISHFPKIISK IIRLPIYVGG GMAAAGSYIA YKMEEASSFT 120
  121 KDKLDRIKDL GESMKEKFNK MFSGDKSQDG GHGNDGTVPT ATLIAATSLD DDESKRQGDP 180
  181 KDDD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [185-510]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DEDDDDEDDE NDSVDTTQDE MLNLTKQMIE IRTILNKVDS SSAHLTLPSI VVIGSQSSGK  60
   61 SSVLESIVGR EFLPKGSNMV TRRPIELTLV NTPNSNNVTA DFPSMRLYNI KDFKEVKRML 120
  121 MELNMAVPTS EAVSEEPIQL TIKSSRVPDL SLVDLPGYIQ VEAADQPIEL KTKIRDLCEK 180
  181 YLTAPNIILA ISAADVDLAN SSALKASKAA DPKGLRTIGV ITKLDLVDPE KARSILNNKK 240
  241 YPLSMGYVGV ITKTPSSINR KHLGLFGEAP SSSLSGIFSK GQHGQSSGEE NTNGLKQIVS 300
  301 HQFEKAYFKE NKKYFTNCQV STKKLR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 506.529817
Match: 1jwyB_
Description: Dynamin G domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.0681607836408 bayes_pls_golite062009
nucleoside-triphosphatase activity 1.737153612961 bayes_pls_golite062009
pyrophosphatase activity 1.66717045339473 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 1.64692747234601 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 1.64482911944641 bayes_pls_golite062009
hydrolase activity 1.16405290417756 bayes_pls_golite062009
motor activity 0.50661339105747 bayes_pls_golite062009
purine nucleotide binding 0.370109410491501 bayes_pls_golite062009
nucleotide binding 0.367488441096941 bayes_pls_golite062009
purine ribonucleotide binding 0.348507955395744 bayes_pls_golite062009
ribonucleotide binding 0.348454114797054 bayes_pls_golite062009
protein binding 0.193768631623192 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [511-902]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EKLIKILEIS MSNALEPTST LIQQELDDTS YLFKVEFNDR HLTPKSYLLN NIDVLKLGIK  60
   61 EFQEKFHRNE LKSILRAELD QKVLDVLATR YWKDDNLQDL SSSKLESDTD MLYWHKKLEL 120
  121 ASSGLTKMGI GRLSTMLTTN AILKELDNIL ESTQLKNHEL IKDLVSNTAI NVLNSKYYST 180
  181 ADQVENCIKP FKYEIDLEER DWSLARQHSI NLIKEELRQC NSRYQAIKNA VGSKKLANVM 240
  241 GYLENESNLQ KETLGMSKLL LERGSEAIFL DKRCKVLSFR LKMLKNKCHS TIEKDRCPEV 300
  301 FLSAVSDKLT STAVLFLNVE LLSDFFYNFP IELDRRLTLL GDEQVEMFAK EDPKISRHIE 360
  361 LQKRKELLEL ALEKIDSILV FKKSYKGVSK NL

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 9.46
Match: 1b89A
Description: Clathrin heavy chain proximal leg segment
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.38363524631144 bayes_pls_golite062009
protein binding 1.63424405980235 bayes_pls_golite062009
protein transporter activity 0.47381617541112 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle