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View Structure Prediction Details

Protein: SLP1
Organism: Saccharomyces cerevisiae
Length: 587 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SLP1.

Description E-value Query
Range
Subject
Range
SLP1 - Integral membrane protein of unknown function; member of the SUN-like family of proteins; genetic in...
SLP1_YEAST - Uncharacterized protein SLP1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SLP1 PE=1 S...
0.0 [1..587] [1..587]
gi|2462835, gi|2... - pir||H86362 hypothetical protein F19G10.15 - Arabidopsis thaliana, gi|2462835|gb|AAB72170.1| hypoth...
0.0 [88..510] [136..536]
SLPI_SCHPO - Uncharacterized protein slp1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPBC3E7.09 PE...
SPBC3E7.09 - Sad1-UNC-like C-terminal
0.0 [45..561] [60..576]
CE28764 - status:Confirmed UniProt:O61794 protein_id:AAC17023.2
3.0E-64 [143..383] [65..325]
gi|7705322, gi|6... - gi|7705322|ref|NP_057311.1| chromosome 1 open reading frame 9 protein isoform 2 [Homo sapiens], gi|6...
1.0E-62 [159..433] [426..694]

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Predicted Domain #1
Region A:
Residues: [1-110]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MANRLLIYGL ILWVSIIGSF ALDRNKTAQN AKIGLHDTTV ITTGSTTNVQ KEHSSPLSTG  60
   61 SLRTHDFRQA SKVDIRQADI RENGERKEQD ALTQPATPRN PGDSSNSFLS 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.202 a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.202 a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like

Predicted Domain #2
Region A:
Residues: [111-517]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FDEWKKVKSK EHSSGPERHL SRVREPVDPS CYKEKECIGE ELEIDLGFLT NKNEWSEREE  60
   61 NQKGFNEEKD IEKVYKKKFN YASLDCAATI VKSNPEAIGA TSTLIESKDK YLLNPCSAPQ 120
  121 QFIVIELCED ILVEEIEIAN YEFFSSTFKR FRVSVSDRIP MVKNEWTILG EFEARNSREL 180
  181 QKFQIHNPQI WASYLKIEIL SHYEDEFYCP ISLIKVYGKS MMDEFKIDQL KAQEDKEQSI 240
  241 GTNNINNLNE QNIQDRCNNI ETRLETPNTS NLSDLAGALS CTSKLIPLKF DEFFKVLNAS 300
  301 FCPSKQMISS SSSSAVPVIP EESIFKNIMK RLSQLETNSS LTVSYIEEQS KLLSKSFEQL 360
  361 EMAHEAKFSH LVTIFNETMM SNLDLLNNFA NQLKDQSLRI LEEQKLE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted functions:

Term Confidence Notes
binding 0.792494243299515 bayes_pls_golite062009
protein binding 0.333723290509725 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [518-587]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NDKFTNRHLL HLERLEKEVS FQRRIVYASF FAFVGLISYL LITRELYFED FEESKNGAIE  60
   61 KADIVQQAIR 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.558 a.28.2 Colicin E immunity proteins
View Download 0.454 a.4.5 "Winged helix" DNA-binding domain
View Download 0.397 a.64.2 Bacteriocin AS-48
View Download 0.351 a.24.17 Group V grass pollen allergen
View Download 0.328 a.118.9 ENTH/VHS domain
View Download 0.323 d.42.1 POZ domain
View Download 0.302 a.101.1 Uteroglobin-like
View Download 0.298 a.60.1 SAM/Pointed domain
View Download 0.292 a.60.2 RuvA domain 2-like
View Download 0.281 a.5.6 Hypothetical protein MTH1615
View Download 0.280 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.278 a.153.1 Nuclear receptor coactivator interlocking domain
View Download 0.276 a.39.1 EF-hand
View Download 0.265 a.4.13 Sigma3 and sigma4 domains of RNA polymerase sigma factors
View Download 0.262 a.60.11 Hypothetical protein YjbJ
View Download 0.258 a.17.1 p8-MTCP1
View Download 0.233 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.231 a.60.1 SAM/Pointed domain
View Download 0.225 a.74.1 Cyclin-like
View Download 0.225 g.23.1 TB module/8-cys domain
View Download 0.222 d.74.2 C-terminal domain of arginine repressor
View Download 0.222 a.159.2 FF domain
View Download 0.217 a.74.1 Cyclin-like
View Download 0.209 d.58.11 EF-G/eEF-2 domains III and V
View Download 0.208 a.4.5 "Winged helix" DNA-binding domain

Predicted functions:

Term Confidence Notes
binding 1.28519067781062 bayes_pls_golite062009
protein binding 1.24709652624798 bayes_pls_golite062009
catalytic activity 0.00204734407654122 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle