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View Structure Prediction Details

Protein: SFL1
Organism: Saccharomyces cerevisiae
Length: 766 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SFL1.

Description E-value Query
Range
Subject
Range
gi|17061847 - gi|17061847|dbj|BAB72173.1| heat shock transcription factor mutant [synthetic construct]
270.0 [0..60] [324..16]
gi|13928966, gi|... - gi|5764553|gb|AAD51329.1|AF172640_1 heat shock factor 2 [Rattus norvegicus], gi|55778284|gb|AAH86554...
270.0 [0..58] [313..3]
gi|76625539 - gi|76625539|ref|XP_587710.2| PREDICTED: similar to Heat shock factor protein 2 (HSF 2) (Heat shock t...
270.0 [0..58] [313..68]
gi|17390978 - gi|17390978|gb|AAH18414.1| Hsf2 protein [Mus musculus]
268.0 [0..58] [313..3]
gi|42415865 - gi|42415865|gb|AAS15800.1| heat shock factor protein hsf8-related [Glycine max]
265.0 [0..31] [326..3]
gi|111305869, gi... - gi|118764049|gb|AAI28421.1| HSF2 protein [Homo sapiens], gi|111305869|gb|AAI21051.1| HSF2 protein [H...
265.0 [0..58] [313..3]
HSF8_SOLLC - Heat shock factor protein HSF8 OS=Solanum lycopersicum GN=HSF8 PE=3 SV=1
265.0 [0..31] [324..7]

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Predicted Domain #1
Region A:
Residues: [1-176]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEEETVSAP APASTPAPAG TDVGSGGAAA GIANAGAEGG DGAEDVKKHG SKMLVGPRPP  60
   61 QNAIFIHKLY QILEDESLHD LIWWTPSGLS FMIKPVERFS KALATYFKHT NITSFVRQLN 120
  121 IYGFHKVSHD HSSNDANSGD DANTNDDSNT HDDNSGNKNS SGDENTGGGV QEKEKS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 144.325697
Match: 1hksA
Description: SOLUTION STRUCTURE OF THE DNA-BINDING DOMAIN OF DROSOPHILA HEAT SHOCK TRANSCRIPTION FACTOR
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [177-294]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NPTKIWEFKH SSGIFKKGDI EGLKHIKRRA SSRNNSSINS RKNSSNQNYD IDSGARVRPS  60
   61 SIQDPSTSSN SFGNFVPQIP GANNSIPEYF NNSHVTYENA NHAPLESNNP EMQEQNRP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [295-370]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PNFQDETLKH LKEINFDMVK IIESMQHFIS LQHSFCSQSF TFKNVSKKKS ENIVKDHQKQ  60
   61 LQAFESDMLT FKQHVM

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.883 a.2.15 Description not found.

Predicted Domain #4
Region A:
Residues: [371-538]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SRAHRTIDSL CAVNAAATAA SVAPAPAPTS TSAYAPKSQY EMMVPPGNQY VPQKSSSTTN  60
   61 IPSRFNTASV PPSQLLYNTN RSRNQHVTYA SEPAHVPNFI NQPIPIQQLP PQYADTFSTP 120
  121 QMMHNPFASK NNNKPGNTKR TNSVLMDPLT PAASVGVQGP LNYPIMNI

[Run NCBI BLAST on this sequence.]

Detection Method: ab initio
Confidence: 14.81
Match:
Description: No description for 1ldvA was found.

Predicted Domain #5
Region A:
Residues: [539-607]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NPSVRDYNKP VPQNMAPSPI YPINEPTTRL YSQPKMRSLG STSSLPNDRR NSPLKLTPRS  60
   61 SLNEDSLYP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [608-766]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPRNSLKSSI SGTSLSSSFT LVANNPAPIR YSQQGLLRSL NKAANCAPDS VTPLDSSVLT  60
   61 GPPPKNMDNL PAVSSNLINS PMNVEHSSSL SQAEPAPQIE LPQPSLPTTS TTKNTGEADN 120
  121 SKRKGSGVYS LLNQEDSSTS SADPKTEDKA APALKKVKM

[Run NCBI BLAST on this sequence.]

Detection Method: ab initio
Confidence: 11.0
Match:
Description: No description for 1deqA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle