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View Structure Prediction Details

Protein: IAH1
Organism: Saccharomyces cerevisiae
Length: 238 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for IAH1.

Description E-value Query
Range		 Subject
Range
gi|151945747 - gi|151945747|gb|EDN63988.1| isoamyl acetate-hydrolyzing esterase [Saccharomyces cerevisiae YJM789]
IAH1 - Isoamyl acetate-hydrolyzing esterase, required in balance with alcohol acetyltransferase to maintain...
IAH1_YEAST - Isoamyl acetate-hydrolyzing esterase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=IAH...
 2.0E-48 [1..238] [1..238]
IAH1_MOUSE - Isoamyl acetate-hydrolyzing esterase 1 homolog OS=Mus musculus GN=Iah1 PE=1 SV=1
 3.0E-42 [3..231] [15..236]
gi|31432667, gi|... - gi|37535366|ref|NP_921985.1| putative esterase [Oryza sativa (japonica cultivar-group)], gb|AAP54272...
 7.0E-41 [4..234] [4..232]
GDL88_ARATH - GDSL esterase/lipase At5g62930 OS=Arabidopsis thaliana GN=At5g62930 PE=2 SV=3
 7.0E-40 [4..235] [3..232]
gi|13161403 - gi|13161403|dbj|BAB33036.1| CPRD49 [Vigna unguiculata]
 3.0E-38 [4..238] [7..241]
IAH1_SCHPO - Isoamyl acetate-hydrolyzing esterase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=iah1 ...
iah1 - isoamyl acetate hydrolytic enzyme Iah1
 2.0E-32 [3..230] [37..244]

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Predicted Domain #1
Region A:
Residues: [1-238] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDYEKFLLFG DSITEFAFNT RPIEDGKDQY ALGAALVNEY TRKMDILQRG FKGYTSRWAL  60
   61 KILPEILKHE SNIVMATIFL GANDACSAGP QSVPLPEFID NIRQMVSLMK SYHIRPIIIG 120
  121 PGLVDREKWE KEKSEEIALG YFRTNENFAI YSDALAKLAN EEKVPFVALN KAFQQEGGDA 180
  181 WQQLLTDGLH FSGKGYKIFH DELLKVIETF YPQYHPKNMQ YKLKDWRDVL DDGSNIMS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 24.30103
Match: 1es9A_
Description: Platelet-activating factor acetylhydrolase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 1.15974340242656 bayes_pls_golite062009
hydrolase activity 0.755660272658182 bayes_pls_golite062009
binding 0.723787843954977 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.39017969987234 bayes_pls_golite062009
protein binding 0.289427729451854 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle