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View Structure Prediction Details

Protein: RKI1
Organism: Saccharomyces cerevisiae
Length: 258 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RKI1.

Description E-value Query
Range		 Subject
Range
gi|190407427 - gi|190407427|gb|EDV10694.1| ribose-5-phosphate ketol-isomerase [Saccharomyces cerevisiae RM11-1a]
RPIA_YEAST - Ribose-5-phosphate isomerase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RKI1 PE=1 S...
RPIA_YEAS7 - Ribose-5-phosphate isomerase OS=Saccharomyces cerevisiae (strain YJM789) GN=RKI1 PE=3 SV=1
RKI1 - Ribose-5-phosphate ketol-isomerase, catalyzes the interconversion of ribose 5-phosphate and ribulose...
 1.0E-85 [1..258] [1..258]
RPIA - ribose 5-phosphate isomerase A
gi|109103776 - gi|109103776|ref|XP_001094618.1| PREDICTED: similar to Ribose-5-phosphate isomerase (Phosphoriboisom...
 2.0E-80 [19..258] [5..234]
RPIA_MOUSE - Ribose-5-phosphate isomerase (EC 5.3.1.6) (Phosphoriboisomerase) - Mus musculus (Mouse)
 3.0E-79 [19..258] [5..234]
gi|18654317 - gi|18654317|gb|AAL77589.1|L43068_1 chloroplast ribose-5-phosphate isomerase [Spinacia oleracea]
 7.0E-78 [11..258] [44..289]
RPI2_ARATH - Probable ribose-5-phosphate isomerase 2 OS=Arabidopsis thaliana GN=RPI2 PE=1 SV=1
 2.0E-77 [12..257] [27..264]
RPIA_PYRAB - Ribose-5-phosphate isomerase A OS=Pyrococcus abyssi GN=rpiA PE=3 SV=1
RPIA_PYRAB - Ribose-5-phosphate isomerase A OS=Pyrococcus abyssi (strain GE5 / Orsay) GN=rpiA PE=3 SV=1
 5.0E-77 [18..255] [3..227]
RPIA_PYRHO - Ribose-5-phosphate isomerase A OS=Pyrococcus horikoshii GN=rpiA PE=1 SV=1
RPIA_PYRHO - Ribose-5-phosphate isomerase A OS=Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 /...
 9.0E-76 [18..255] [3..227]
RPIA_PYRFU - Ribose-5-phosphate isomerase A OS=Pyrococcus furiosus GN=rpiA PE=3 SV=1
RPIA_PYRFU - Ribose-5-phosphate isomerase A OS=Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1...
 4.0E-74 [18..255] [3..227]
gi|25329436 - pir||AE1917 ribose 5-phosphate isomerase [imported] - Nostoc sp. (strain PCC 7120)
RPIA_NOSS1 - Ribose-5-phosphate isomerase A OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=rpiA PE=3 SV=1
 6.0E-72 [15..256] [5..234]

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Predicted Domain #1
Region A:
Residues: [1-148] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAGVPKIDA LESLGNPLED AKRAAAYRAV DENLKFDDHK IIGIGSGSTV VYVAERIGQY  60
   61 LHDPKFYEVA SKFICIPTGF QSRNLILDNK LQLGSIEQYP RIDIAFDGAD EVDENLQLIK 120
  121 GGGACLFQEK LVSTSAKTFI VVADSRKK

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [238-258] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IDNASKAYFG NSDGSVEVTE K

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 418.071898
Match: 1lk5A_
Description: D-ribose-5-phosphate isomerase (RpiA), catalytic domain; D-ribose-5-phosphate isomerase (RpiA), lid domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [149-237] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPKHLGKNWR QGVPIEIVPS SYVRVKNDLL EQLHAEKVDI RQGGSAKAGP VVTDNNNFII  60
   61 DADFGEISDP RKLHREIKLL VGVVETGLF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 418.071898
Match: 1lk5A_
Description: D-ribose-5-phosphate isomerase (RpiA), catalytic domain; D-ribose-5-phosphate isomerase (RpiA), lid domain
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle