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View Structure Prediction Details

Protein: YSP3
Organism: Saccharomyces cerevisiae
Length: 478 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YSP3.

Description E-value Query
Range
Subject
Range
YSP3_YEAST - Subtilisin-like protease 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YSP3 PE=2 SV=...
YSP3 - Putative precursor to the subtilisin-like protease III
0.0 [1..478] [1..478]
ALP2_ASPFC - Alkaline protease 2 OS=Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) GN=alp2 PE=3 SV...
gi|2143220, gi|5... - gi|5139328|emb|CAB45520.1| serine proteinase [Aspergillus fumigatus], gi|2143220|emb|CAA73782.1| cel...
ALP2_ASPFU - Alkaline protease 2 OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)...
0.0 [37..471] [5..444]
gi|15808807 - gi|15808807|gb|AAL08510.1|AF413106_1 subtilase [Ophiostoma piliferum]
0.0 [34..471] [1..444]
gi|171680111 - gi|171680111|ref|XP_001905001.1| unnamed protein product [Podospora anserina]
gi|7400480, gi|1... - gi|7400480|gb|AAC03564.2| subtilisin-like serine protease [Podospora anserina], gi|170939682|emb|CAP...
0.0 [38..471] [5..452]
gi|17402485 - gi|17402485|emb|CAD13274.1| protease PR1H [Metarhizium anisopliae var. anisopliae]
gi|17402485 - gi|17402485|emb|CAD13274.1| protease PR1H [Metarhizium anisopliae var. anisopliae]
0.0 [32..471] [3..458]
gi|17385556 - gi|17385556|emb|CAC85639.1| serine protease 2 [Pyrenopeziza brassicae]
0.0 [35..471] [3..447]

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Predicted Domain #1
Region A:
Residues: [1-68]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKFSTILPIL WANCCLCMII PDFDGIVRFI ENIDGTRSVR AGEGLGQHDP GNFHTEHQHV  60
   61 AHKTEFLP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [69-172]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YRYVIVFNED ISLQQIQSHM QVVQKDHSTS VGKLTENDAF WRVISSSVSS KSQFGGIDNF  60
   61 FDINGLFRGY TGYFTDEIIK IISQDPIIKF VEQETTVKIS NSSL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.0
Match: 1kn6A_
Description: Prohormone convertase 1 pro-domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 4.68838733699853 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 4.20928698248021 bayes_pls_golite062009
endopeptidase activity 3.45296270246929 bayes_pls_golite062009
hydrolase activity 3.36483239319728 bayes_pls_golite062009
serine hydrolase activity 1.90036575189745 bayes_pls_golite062009
serine-type peptidase activity 1.89198766955068 bayes_pls_golite062009
binding 1.85875472341221 bayes_pls_golite062009
serine-type endopeptidase activity 1.23150012549143 bayes_pls_golite062009
catalytic activity 0.597535457699629 bayes_pls_golite062009
protein binding 0.380935140681308 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [173-478]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QEEAPWGLHR VSHREKPKYG QDLEYLYEDA AGKGVTSYVL DTGIDTEHED FEGRAEWGAV  60
   61 IPANDEASDL NGHGTHCAGI IGSKHFGVAK NTKIVAVKVL RSNGEGTVSD VIKGIEYVTK 120
  121 EHIESSKKKN KEFKGSTANL SLGSSKSLAM EMAVNAAVDS GVHFAIAAGN EDEDACLSSP 180
  181 AGAEKSITVG ASTFSDDRAF FSNWGTCVDV FAPGINIMST YIGSRNATLS LSGTSMASPH 240
  241 VAGILSYFLS LQPAPDSEFF NDAPSPQELK EKVLKFSTQG VLGDIGDDTP NKLIYNGGGK 300
  301 KLDGFW

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 565.67837
Match: 1ic6A_
Description: Proteinase K
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle