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View Structure Prediction Details

Protein: INO4
Organism: Saccharomyces cerevisiae
Length: 151 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for INO4.

Description E-value Query
Range
Subject
Range
INO4_YEAST - Protein INO4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=INO4 PE=1 SV=1
gi|151945526 - gi|151945526|gb|EDN63767.1| basic helix-loop-helix (bHLH) protein [Saccharomyces cerevisiae YJM789]
INO4 - Transcription factor required for derepression of inositol-choline-regulated genes involved in phosp...
gi|190407243 - gi|190407243|gb|EDV10510.1| basic helix-loop-helix protein [Saccharomyces cerevisiae RM11-1a]
7.0E-72 [1..151] [1..151]
gi|18026956 - gi|18026956|gb|AAL55711.1|AF251689_1 putative transcription factor BHLH4 [Arabidopsis thaliana]
5.0E-4 [16..123] [382..495]
MYCS_RAT - Protein S-Myc OS=Rattus norvegicus GN=Mycs PE=3 SV=1
9.0E-4 [29..104] [330..405]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.007 [16..108] [430..525]

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Predicted Domain #1
Region A:
Residues: [1-151]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTNDIKEIQT IQPGLSEIKE IKGELANVKK RKRRSKKINK LTDGQIRINH VSSEKKRREL  60
   61 ERAIFDELVA VVPDLQPQES RSELIIYLKS LSYLSWLYER NEKLRKQIIA KHEAKTGSSS 120
  121 SSDPVQEQNG NIRDLVPKEL IWELGDGQSG Q

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 10.92
Match: 1hloA
Description: Max protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.08855036296174 bayes_pls_golite062009
DNA binding 4.87243318281876 bayes_pls_golite062009
nucleic acid binding 4.77537175825177 bayes_pls_golite062009
transcription factor activity 4.43134840465732 bayes_pls_golite062009
binding 3.63719401349018 bayes_pls_golite062009
transcription activator activity 3.62180682771335 bayes_pls_golite062009
sequence-specific DNA binding 3.17029130860224 bayes_pls_golite062009
RNA polymerase II transcription factor activity 3.11931609869373 bayes_pls_golite062009
protein binding 2.53793947976093 bayes_pls_golite062009
transcription factor binding 2.33137487648005 bayes_pls_golite062009
RNA polymerase II transcription factor activity, enhancer binding 2.01283700957804 bayes_pls_golite062009
transcription cofactor activity 1.30186253699056 bayes_pls_golite062009
transcription repressor activity 0.828519845330998 bayes_pls_golite062009
transcription corepressor activity 0.560586077390024 bayes_pls_golite062009
promoter binding 0.531949034115114 bayes_pls_golite062009
protein heterodimerization activity 0.328788240668351 bayes_pls_golite062009
transcription coactivator activity 0.172100901723138 bayes_pls_golite062009
protein dimerization activity 0.0815596840205237 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle