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View Structure Prediction Details

Protein: ARG1
Organism: Saccharomyces cerevisiae
Length: 420 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ARG1.

Description E-value Query
Range		 Subject
Range
ASSY_RAT - Argininosuccinate synthase OS=Rattus norvegicus GN=Ass1 PE=1 SV=1
 0.0 [2..411] [3..406]
HGNC:758|MIM:603... - synthase 1
gi|190691653, gi... - gi|190691653|gb|ACE87601.1| argininosuccinate synthetase 1 protein [synthetic construct], gi|1906902...
ASS1 - argininosuccinate synthase 1
 0.0 [2..411] [3..406]
gi|55249915 - gb|AAH86119.1| Unknown (protein for MGC:98519) [Xenopus laevis]
ASSY_MOUSE - Argininosuccinate synthase OS=Mus musculus GN=Ass1 PE=1 SV=1
 0.0 [2..411] [3..406]
ASSY_BOVIN - Argininosuccinate synthase OS=Bos taurus GN=ASS1 PE=2 SV=1
 0.0 [1..411] [1..406]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 0.0 [1..411] [1..406]
ASSY_THEMA - Argininosuccinate synthase OS=Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) ...
ASSY_THEMA - Argininosuccinate synthase OS=Thermotoga maritima GN=argG PE=1 SV=1
 0.0 [2..416] [1..409]
ARG1 - Arginosuccinate synthetase, catalyzes the formation of L-argininosuccinate from citrulline and L-asp...
 0.0 [1..420] [1..420]
ASSY_BACHD - Argininosuccinate synthase OS=Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM...
ASSY_BACHD - Argininosuccinate synthase OS=Bacillus halodurans GN=argG PE=3 SV=1
 0.0 [1..411] [1..395]
ASSY_ARATH - Argininosuccinate synthase, chloroplastic OS=Arabidopsis thaliana GN=At4g24830 PE=1 SV=3
 0.0 [4..413] [126..522]
gi|221324414 - gi|221324414|ref|ZP_03605708.1| argininosuccinate synthase [Bacillus subtilis subsp. subtilis str. S...
gi|221315214 - gi|221315214|ref|ZP_03597019.1| argininosuccinate synthase [Bacillus subtilis subsp. subtilis str. N...
gi|221320132 - gi|221320132|ref|ZP_03601426.1| argininosuccinate synthase [Bacillus subtilis subsp. subtilis str. J...
ASSY_BACSU - Argininosuccinate synthase OS=Bacillus subtilis (strain 168) GN=argG PE=3 SV=1
ASSY_BACSU - Argininosuccinate synthase OS=Bacillus subtilis GN=argG PE=3 SV=1
 0.0 [1..412] [1..397]

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Predicted Domain #1
Region A:
Residues: [1-63] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKGKVCLAY SGGLDTSVIL AWLLDQGYEV VAFMANVGQE EDFDAAKEKA LKIGACKFVC  60
   61 VDC

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [95-177] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PVIAKAQIDV AKQEGCFAVS HGCTGKGNDQ IRFELSFYAL KPDVKCITPW RMPEFFERFA  60
   61 GRKDLLDYAA QKGIPVAQTK AKP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1081.9897
Match: 1kh1A_
Description: Argininosuccinate synthetase, N-terminal domain; Argininosuccinate synthetase, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [64-94] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 REDFVKDILF PAVQVNAVYE DVYLLGTSLA R

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [178-208] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WSTDENQAHI SYEAGILEDP DTTPPKDMWK L

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [268-287] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RIDIVEDRYI NLKSRGCYEQ

[Run NCBI BLAST on this sequence.]

Region D:
Residues: [310-345] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RQLRDSFVTP NYSRLIYNGF LLHPECEYIR SMIQPS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1081.9897
Match: 1kh1A_
Description: Argininosuccinate synthetase, N-terminal domain; Argininosuccinate synthetase, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [209-267] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IVDPMDAPDQ PQDLTIDFER GLPVKLTYTD NKTSKEVSVT KPLDVFLAAS NLARANGVG

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [288-309] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 APLTVLRKAH VDLEGLTLDK EV

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [346-420] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QNSVNGTVRV RLYKGNVIIL GRSTKTEKLY DPTESSMDEL TGFLPTDTTG FIAIQAIRIK  60
   61 KYGESKKTKG EELTL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1081.9897
Match: 1kh1A_
Description: Argininosuccinate synthetase, N-terminal domain; Argininosuccinate synthetase, C-terminal domain
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle