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View Structure Prediction Details

Protein: SPE2
Organism: Saccharomyces cerevisiae
Length: 396 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPE2.

Description E-value Query
Range		 Subject
Range
SPE2 - S-adenosylmethionine decarboxylase, required for the biosynthesis of spermidine and spermine; cells ...
gi|151945583 - gi|151945583|gb|EDN63824.1| spermidine resistance protein [Saccharomyces cerevisiae YJM789]
gi|207341367 - gi|207341367|gb|EDZ69444.1| YOL052Cp-like protein [Saccharomyces cerevisiae AWRI1631]
gi|190407294 - gi|190407294|gb|EDV10561.1| S-adenosylmethionine decarboxylase proenzyme [Saccharomyces cerevisiae R...
DCAM_YEAST - S-adenosylmethionine decarboxylase proenzyme OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c...
 0.0 [1..396] [1..396]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 0.0 [19..394] [3..336]
DCAM_TOBAC - S-adenosylmethionine decarboxylase proenzyme OS=Nicotiana tabacum GN=SAMDC PE=2 SV=1
 0.0 [19..394] [3..336]
DCAM_NICSY - S-adenosylmethionine decarboxylase proenzyme OS=Nicotiana sylvestris GN=SAMDC1 PE=2 SV=1
 0.0 [20..394] [4..336]
DCAM_SOLTU - S-adenosylmethionine decarboxylase proenzyme OS=Solanum tuberosum GN=SAMDC PE=1 SV=1
 0.0 [21..394] [5..336]
DCAM_DATST - S-adenosylmethionine decarboxylase proenzyme OS=Datura stramonium GN=SAMDC PE=2 SV=1
 0.0 [21..394] [5..336]
gi|19526455 - gi|19526455|gb|AAL89723.1|AF488307_1 S-adenosylmethionine decarboxylase [Glycine max]
 0.0 [20..394] [2..334]
DCAM_VICFA - S-adenosylmethionine decarboxylase proenzyme OS=Vicia faba GN=SAMDC PE=2 SV=1
 0.0 [21..394] [1..332]
DCAM2_BRAJU - S-adenosylmethionine decarboxylase proenzyme 2 OS=Brassica juncea GN=SAMDC2 PE=2 SV=1
 0.0 [21..394] [1..337]

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Predicted Domain #1
Region A:
Residues: [1-199] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTVTIKELTN HNYIDHELSA TLDSTDAFEG PEKLLEIWFF PHKKSITTEK TLRNIGMDRW  60
   61 IEILKLVKCE VLSMKKTKEL DAFLLSESSL FVFDHKLTMK TCGTTTTLFC LEKLFQIVEQ 120
  121 ELSWAFRTTQ GGKYKPFKVF YSRRCFLFPC KQAAIHQNWA DEVDYLNKFF DNGKSYSVGR 180
  181 NDKSNHWNLY VTETDRSTP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 487.0
Match: 1jl0A_
Description: S-adenosylmethionine decarboxylase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
adenosylmethionine decarboxylase activity 6.97190143843809 bayes_pls_golite062009
carbon-carbon lyase activity 2.68228786608236 bayes_pls_golite062009
carboxy-lyase activity 1.55250570844159 bayes_pls_golite062009
binding 1.4725833406744 bayes_pls_golite062009
catalytic activity 1.25843830926101 bayes_pls_golite062009
lyase activity 0.834955527171148 bayes_pls_golite062009
protein binding 0.443666756110255 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [200-396] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KGKEYIEDDD ETFEVLMTEL DPECASKFVC GPEASTTALV EPNEDKGHNL GYQMTKNTRL  60
   61 DEIYVNSAQD SDLSFHHDAF AFTPCGYSSN MILAEKYYYT LHVTPEKGWS YASFESNIPV 120
  121 FDISQGKQDN LDVLLHILNV FQPREFSMTF FTKNYQNQSF QKLLSINESL PDYIKLDKIV 180
  181 YDLDDYHLFY MKLQKKI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 487.0
Match: 1jl0A_
Description: S-adenosylmethionine decarboxylase
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle