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View Structure Prediction Details

Protein: SMC5
Organism: Saccharomyces cerevisiae
Length: 1093 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SMC5.

Description E-value Query
Range
Subject
Range
MYH4_PIG - Myosin-4 OS=Sus scrofa GN=MYH4 PE=2 SV=1
0.0 [81..993] [862..1807]
gi|9800488, gi|1... - gi|9800488|gb|AAF99315.1|AF272034_1 fast myosin heavy chain isoform 3 [Gallus gallus], gi|165973976|...
0.0 [81..993] [865..1810]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [81..993] [865..1810]
MYH1 - myosin, heavy chain 1, skeletal muscle, adult
0.0 [81..993] [864..1809]
MYH2_BOVIN - Myosin-2 OS=Bos taurus GN=MYH2 PE=2 SV=1
0.0 [87..993] [871..1810]

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Predicted Domain #1
Region A:
Residues: [1-126]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSLIDLGRY VERTHHGEDT EPRSKRVKIA KPDLSSFQPG SIIKIRLQDF VTYTLTEFNL  60
   61 SPSLNMIIGP NGSGKSTFVC AVCLGLAGKP EYIGRSKKVE DFIKNGQDVS KIEITLKNSP 120
  121 NVTDIE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.0
Match: 1ii8A_
Description: Rad50
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [127-283]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YIDARDETIK ITRIITRSKR RSDYLINDYQ VSESVVKTLV AQLNIQLDNL CQFLSQERVE  60
   61 EFARLKSVKL LVETIRSIDA SLLDVLDELR ELQGNEQSLQ KDLDFKKAKI VHLRQESDKL 120
  121 RKSVESLRDF QNKKGEIELH SQLLPYVKVK DHKEKLN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 23.69897
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [284-300]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IYKEEYERAK ANLRAIL

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [372-404]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TIISTKEDFL RSQEILAQTH LPEKSVFEDI DIK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 2.154902
Match: 1cii__
Description: Colicin Ia; Colicin Ia, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [301-371]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KDKKPFANTK KTLENQVEEL TEKCSLKTDE FLKAKEKINE IFEKLNTIRD EVIKKKNQNE  60
   61 YYRGRTKKLQ A

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [405-435]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RKEIINKEGE IRDLISEIDA KANAINHEMR S

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 2.154902
Match: 1cii__
Description: Colicin Ia; Colicin Ia, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [436-713]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IQRQAESKTK SLTTTDKIGI LNQDQDLKEV RDAVLMVREH PEMKDKILEP PIMTVSAINA  60
   61 QFAAYLAQCV DYNTSKALTV VDSDSYKLFA NPILDKFKVN LRELSSADTT PPVPAETVRD 120
  121 LGFEGYLSDF ITGDKRVMKM LCQTSKIHTI PVSRRELTPA QIKKLITPRP NGKILFKRII 180
  181 HGNRLVDIKQ SAYGSKQVFP TDVSIKQTNF YQGSIMSNEQ KIRIENEIIN LKNEYNDRKS 240
  241 TLDALSNQKS GYRHELSELA SKNDDINREA HQLNEIRK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 2.154902
Match: 1cii__
Description: Colicin Ia; Colicin Ia, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [714-903]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KYTMRKSTIE TLREKLDQLK REARKDVSQK IKDIDDQIQQ LLLKQRHLLS KMASSMKSLK  60
   61 NCQKELISTQ ILQFEAQNMD VSMNDVIGFF NEREADLKSQ YEDKKKFVKE MRDTPEFQSW 120
  121 MREIRSYDQD TKEKLNKVAE KYEEEGNFNL SFVQDVLDKL ESEIAMVNHD ESAVTILDQV 180
  181 TAELRELEHT 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.522879
Match: 1c1gA_
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted Domain #7
Region A:
Residues: [904-1093]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VPQQSKDLET IKAKLKEDHA VLEPKLDDIV SKISARFARL FNNVGSAGAV RLEKPKDYAE  60
   61 WKIEIMVKFR DNAPLKKLDS HTQSGGERAV STVLYMIALQ EFTSAPFRVV DEINQGMDSR 120
  121 NERIVHKAMV ENACAENTSQ YFLITPKLLT GLHYHEKMRI HCVMAGSWIP NPSEDPKMIH 180
  181 FGETSNYSFD 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.522879
Match: 1e69A_
Description: Smc head domain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle