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View Structure Prediction Details

Protein: MNT4
Organism: Saccharomyces cerevisiae
Length: 580 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MNT4.

Description E-value Query
Range
Subject
Range
MNT4_YEAST - Probable alpha-1,3-mannosyltransferase MNT4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c)...
MNT4 - Putative alpha-1,3-mannosyltransferase, not required for protein O-glycosylation
0.0 [1..580] [1..580]

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Predicted Domain #1
Region A:
Residues: [1-181]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVLRIRRIKK LAPLIFTSLL SLIVLFRVYR QYPFSDHFET RREDDRSGNV HCFSRLRQIE  60
   61 EYEKPELTSK FYEPNRWKSF ISYVTRSRKD VKTVSRSLSN LDLYQKCSKE IRADQDISLL 120
  121 HSIETKLFPY INFTALNSEQ SHNFWPVHTR FDGTKYRGQV LQFSSENNSF IGTSPIEFKA 180
  181 S

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [182-361]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EPFWENWLNS ALQRNSKGVV MSVSEYLVAD TIRLIRVLRL LNNSLPIEIV HKSDLHESSQ  60
   61 QLLIAAARES GSLNYPPQEL WFLDVKDMLN DEYLARFKRF SNKWLAITFC SFQIPIFLDS 120
  121 DTVPFVPLDT LYEIDGFKRT GTLFFKDRSF PTSKLSPLQV KVLKQIINNS LDVSSDSEQG 180
  181 

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.02
Match: 1ga8A
Description: Galactosyltransferase LgtC
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
mannosyltransferase activity 2.72970569728159 bayes_pls_golite062009
transferase activity 2.3313878748424 bayes_pls_golite062009
transferase activity, transferring glycosyl groups 2.31282143022166 bayes_pls_golite062009
catalytic activity 1.73979371332125 bayes_pls_golite062009
transferase activity, transferring hexosyl groups 1.64579615957842 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.58983046450767 bayes_pls_golite062009
UDP-glycosyltransferase activity 1.18238034321908 bayes_pls_golite062009
binding 0.809446708810115 bayes_pls_golite062009
alpha-1,2-mannosyltransferase activity 0.373609073759347 bayes_pls_golite062009
nucleotidyltransferase activity 0.355405833568127 bayes_pls_golite062009
acetylgalactosaminyltransferase activity 0.130891646999536 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [362-580]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FEILKHNLND EMAIDAIEAL IFKKQKHYMD SGLVIFDKQK HFFCLPIAIM LQFSPIQEFF  60
   61 HGDKEWFWLS LFISKKEFTF YPIEASNVGR LEKPETLESS TICSTQLSHT DVYGNLLWLN 120
  121 GGLSVCKKNC WNYDFTKRKE IAAKYKSVDE LRNYYQSPVK LEAVIIPDVS KSPWSQQSEC 180
  181 VMYSYCTHYR KGQYGKLIEF TDSQKKYYEK VVELWNKVV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle