| Protein: | SSK2 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1579 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SSK2.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [211..1544] | [22..1296] |
|
|
0.0 | [148..874] | [96..804] |
|
|
0.0 | [191..876] | [65..720] |
|
|
0.0 | [1027..1578] | [504..1075] |
|
|
0.0 | [1022..1571] | [30..583] |
|
Region A: Residues: [1-560] |
1 11 21 31 41 51
| | | | | |
1 MSHSDYFNYK PYGDSTEKPS SSKMRQSSSS SSSRLRSESL GRNSNTTQAR VASSPISPGL 60
61 HSTQYFRSPN AVYSPGESPL NTVQLFNRLP GIPQGQFFHQ NAISGSSSSS ARSSRRPSNI 120
121 GLPLPKNPQQ SLPKLSTQPV PVHKKVEASK TESEIIKKPA PVNSNQDPLL TTPTLVISPE 180
181 LASLNTTNTS IMSTPQNITN QTSNKHIPTR SQPNGSTSSS TLQDIVTTNS SQRSVGHHGG 240
241 STTSLRTYKK QYVLNEQLYL RKMRNRANDD YYTRGIVASS NFEDDEENFS NKGEDDLELE 300
301 MDDLLKVEGE DKDNDFNFGY NFITSSTKNN ENVVSMSLNY LKGKLDWLRD VNNDQPCEIE 360
361 DEEWHSILGS EDLLSKLLQN PMVNNRFEWQ TMLSKVLKGD IVRNEKTKIA NQGKGPGFNT 420
421 QFSDDIWIEL KAWMNGRTVE DQNKSLRIFR DSTDSVFQEI MAFKLEDNMS ADEAAETIKS 480
481 LVDKYYRVLN LWPNIKRMHA EKPITKTEAF RNRIDTLNSW LNFKFNFDTN IAYLKKWIVG 540
541 NKELESTTEV DNTTVNLDDP
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [561-886] |
1 11 21 31 41 51
| | | | | |
1 AVFATNCKRF AEQIMKEKDI ELIFQKKIFF PLAPWILKAK FFFLKYQKTW NELNLSYLDQ 60
61 DLEFLLMFPM RLVKDIILIR LSYAKKIQNP TLMMIDQMMD DFSTYIKLAV QMKFTVASYC 120
121 NDWFFKVKID PEFDHTVVEG LEYFFSILEL RILYSGKNSF KTSKEPDLLL KYWEMFRNVG 180
181 YYIDDAGELI AAEFTKLTLR LVHRLHAYLL RQQNTPPKLE NEAAAEKWLV QIFEILGSMK 240
241 RKLNRFTNIL TKAFQNFVRY KIEDHNYLLK QLKETGHFLI YTGGYLEQNG TYLIGSPELL 300
301 GCKDDDILRI IKNSDIGCDL VPKLEI
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [887-1123] |
1 11 21 31 41 51
| | | | | |
1 NNSLTIYNAL DDNWNSNSSL GSDISNDGTP FYYIKNDLTT QPRSYNGNRV NREPDFENSR 60
61 STEEEFYELE TRLNSLGYVL VLTPQEPLLW EGEMYNLSDN KTIKPEGLNL KVIPNSIDLM 120
121 CQGSSYALEY QCDRFQQISG SSVSFLEKKS SSETVKNNLQ RINKAYFRCT YSVLKNYTKI 180
181 VTTFKKVSPV NDLLNNIFLF GRDFGLNFLR INVANNEKRS IIILLMMRLS IGWLKFL
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1124-1256] |
1 11 21 31 41 51
| | | | | |
1 AEDCDPTDQR VFRWCVTSME FAMHMVSGWN ILALDECQFS SLKQKISECM SLLISHFDII 60
61 GARSIEVEKI NQQARSNLDL EDVFDDDMML QVNSEFRVQS IMELEERIKR NPHQTGKVID 120
121 DSDKGNKYLV SLA
|
| Detection Method: | |
| Confidence: | 3.522879 |
| Match: | 1gxcA_ |
| Description: | Chk2 kinase |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1257-1346] |
1 11 21 31 41 51
| | | | | |
1 SSISNVSMRW QKRNFIGGGT FGRVYSAVDL DNGEILAVKE INIQDSKSMQ KIFPLIKEEM 60
61 SVLEILNHPN IVSYYGVEVH RDKVNIFMEY
|
| Detection Method: | |
| Confidence: | 380.54902 |
| Match: | 1f3mC_ |
| Description: | pak1 |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1347-1579] |
1 11 21 31 41 51
| | | | | |
1 CEGGSLAALL EHGRIEDEMV TQVYTLQLLE GLAYLHESGI VHRDVKPENI LLDFNGVIKY 60
61 VDFGAAKKIA NNGTRLASMN KIENADGEHE DVTHVSDSKA VKNNENALLD MMGTPMYMAP 120
121 ESITGSTTKG KLGADDVWSL GCVVLEMITG RRPWANLDNE WAIMYHVAAG HTPQFPTKDE 180
181 VSSAGMKFLE RCLIQNPSKR ASAVELLMDP WIVQIREIAF GDDSSSTDTE ERE
|
| Detection Method: | |
| Confidence: | 380.54902 |
| Match: | 1f3mC_ |
| Description: | pak1 |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [934-1126] |
1 11 21 31 41 51
| | | | | |
1 NRVNREPDFE NSRSTEEEFY ELETRLNSLG YVLVLTPQEP LLWEGEMYNL SDNKTIKPEG 60
61 LNLKVIPNSI DLMCQGSSYA LEYQCDRFQQ ISGSSVSFLE KKSSSETVKN NLQRINKAYF 120
121 RCTYSVLKNY TKIVTTFKKV SPVNDLLNNI FLFGRDFGLN FLRINVANNE KRSIIILLMM 180
181 RLSIGWLKFL AED
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1127-1204] |
1 11 21 31 41 51
| | | | | |
1 CDPTDQRVFR WCVTSMEFAM HMVSGWNILA LDECQFSSLK QKISECMSLL ISHFDIIGAR 60
61 SIEVEKINQQ ARSNLDLE
|
| Detection Method: | |
| Confidence: | 4.522879 |
| Match: | 1gxcA |
| Description: | Chk2 kinase |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1205-1579] |
1 11 21 31 41 51
| | | | | |
1 DVFDDDMMLQ VNSEFRVQSI MELEERIKRN PHQTGKVIDD SDKGNKYLVS LASSISNVSM 60
61 RWQKRNFIGG GTFGRVYSAV DLDNGEILAV KEINIQDSKS MQKIFPLIKE EMSVLEILNH 120
121 PNIVSYYGVE VHRDKVNIFM EYCEGGSLAA LLEHGRIEDE MVTQVYTLQL LEGLAYLHES 180
181 GIVHRDVKPE NILLDFNGVI KYVDFGAAKK IANNGTRLAS MNKIENADGE HEDVTHVSDS 240
241 KAVKNNENAL LDMMGTPMYM APESITGSTT KGKLGADDVW SLGCVVLEMI TGRRPWANLD 300
301 NEWAIMYHVA AGHTPQFPTK DEVSSAGMKF LERCLIQNPS KRASAVELLM DPWIVQIREI 360
361 AFGDDSSSTD TEERE
|
| Detection Method: | |
| Confidence: | 113.0 |
| Match: | 2esmA |
| Description: | Crystal Structure of ROCK 1 bound to fasudil |
Matching Structure (courtesy of the PDB): |
|
