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View Structure Prediction Details

Protein: COS1
Organism: Saccharomyces cerevisiae
Length: 381 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for COS1.

Description E-value Query
Range
Subject
Range
COS2, COS3 - Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-enc...
COS2_YEAST, COS3... - Protein COS3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=COS3 PE=1 SV=1, Protein COS...
597.0 [0..1] [377..1]

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Predicted Domain #1
Region A:
Residues: [1-61]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKENELKNEK SVDVLSFKQL ESQKIVLPQD LFRSSFTWFC YEIYKSLAFR IWMLLWLPLS  60
   61 V

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [62-171]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WWKLSNNCIY PLIVSLLVLF LGPIFVLVIC GLSRKRSLSK QLIQFCKEVT ENTPSSDPHD  60
   61 WEVVAANLNS YLYENKAWNT KYFFFNAMVC QEAFRTTLLE PFSLKKDEAA 

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 52.443697
Match: PF00674
Description: DUP family

Shown below is our most confident prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.815 N/A N/A a.186.1 Description not found.

Predicted Domain #3
Region A:
Residues: [172-241]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KVKSFKDSVP YIEEALGVYF REVEKQWKLF NSEKSWSPVG LEDAKLPKEA YRFKLTWFLK  60
   61 RISNIFMLIP 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [242-381]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FLNFLCCIYV SRGMCLLLRT FYLGWILFML VQGFQNMRMI VLSVKMEHKM QFLSTIINEQ  60
   61 ESGANGWDEI AKKMNRYLFE KKVWKNEEFF FDGIDCEWFF SHFFYRVLSA KKSMRALSLN 120
  121 VELWPYIKEA QLSCSEESLA 

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 61.008774
Match: PF00674
Description: DUP family

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle