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View Structure Prediction Details

Protein: NAR1
Organism: Saccharomyces cerevisiae
Length: 491 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NAR1.

Description E-value Query
Range		 Subject
Range
gi|207341882 - gi|207341882|gb|EDZ69818.1| YNL240Cp-like protein [Saccharomyces cerevisiae AWRI1631]
NAR1_YEAST - Cytosolic Fe-S cluster assembly factor NAR1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c)...
NAR1 - Component of the cytosolic iron-sulfur (FeS) protein assembly machinery, required for maturation of ...
 0.0 [1..491] [1..491]
gi|4927278 - gi|4927278|gb|AAD33071.1| hydrogenase-1 [Clostridium thermocellum]
 0.0 [1..474] [135..574]
gi|158276727, gi... - gi|29165649|gb|AAM01186.2| Fe-only hydrogenase precursor [Chlamydomonas reinhardtii], gi|18026272|gb...
 0.0 [40..477] [36..502]
gi|14250935 - gi|14250935|emb|CAC39231.1| HymC protein [Eubacterium acidaminophilum]
 0.0 [1..474] [135..575]
NARFL - nuclear prelamin A recognition factor-like
 0.0 [2..491] [6..476]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 0.0 [2..477] [141..583]
gi|7433127 - pir||C72405 hydrogenase (EC 1.18.99.1) (Fe) large chain [similarity] - Thermotoga maritima (strain M...
gi|15642974, gi|... - gi|4980698|gb|AAD35293.1|AE001705_4 NADP-reducing hydrogenase, subunit D, putative [Thermotoga marit...
 0.0 [2..468] [163..593]
NAR1_ARATH - Protein NAR1 OS=Arabidopsis thaliana GN=NAR1 PE=1 SV=1
 0.0 [2..485] [6..457]
gi|19547863 - gi|19547863|gb|AAK60409.1| hydrogenase [Neocallimastix frontalis]
 0.0 [8..474] [184..623]
PHF1_CLOPA - Iron hydrogenase 1 OS=Clostridium pasteurianum PE=1 SV=1
 0.0 [9..473] [143..574]

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Predicted Domain #1
Region A:
Residues: [1-491] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSALLSESDL NDFISPALAC VKPTQVSGGK KDNVNMNGEY EVSTEPDQLE KVSITLSDCL  60
   61 ACSGCITSSE EILLSSQSHS VFLKNWGKLS QQQDKFLVVS VSPQCRLSLA QYYGLTLEAA 120
  121 DLCLMNFFQK HFQCKYMVGT EMGRIISISK TVEKIIAHKK QKENTGADRK PLLSAVCPGF 180
  181 LIYTEKTKPQ LVPMLLNVKS PQQITGSLIR ATFESLAIAR ESFYHLSLMP CFDKKLEASR 240
  241 PESLDDGIDC VITPREIVTM LQELNLDFKS FLTEDTSLYG RLSPPGWDPR VHWASNLGGT 300
  301 CGGYAYQYVT AVQRLHPGSQ MIVLEGRNSD IVEYRLLHDD RIIAAASELS GFRNIQNLVR 360
  361 KLTSGSGSER KRNITALRKR RTGPKANSRE MAAATAATAD PYHSDYIEVN ACPGACMNGG 420
  421 GLLNGEQNSL KRKQLVQTLN KRHGEELAMV DPLTLGPKLE EAAARPLSLE YVFAPVKQAV 480
  481 EKDLVSVGST W

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 334.0103
Match: 1c4aA_
Description: Fe-only hydrogenase, catalytic domain; Fe-only hydrogenase, N-terminal domain; Fe-only hydrogenase, second domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.47874003627413 bayes_pls_golite062009
NADH dehydrogenase (ubiquinone) activity 1.31458462821219 bayes_pls_golite062009
iron-sulfur cluster binding 1.18054918348653 bayes_pls_golite062009
metal cluster binding 1.18054918348653 bayes_pls_golite062009
NADH dehydrogenase activity 1.10428419414285 bayes_pls_golite062009
lamin binding 0.863386378061341 bayes_pls_golite062009
NADH dehydrogenase (quinone) activity 0.778342926116907 bayes_pls_golite062009
catalytic activity 0.488483980994331 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor 0.312816353615077 bayes_pls_golite062009
ferredoxin hydrogenase activity 0.278768281741128 bayes_pls_golite062009
oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor 0.278768281741128 bayes_pls_golite062009
protein binding 0.221871950373022 bayes_pls_golite062009
electron carrier activity 0.0554226204149908 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle