| Protein: | KEX2 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 814 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for KEX2.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..814] | [1..814] |
|
|
0.0 | [5..755] | [2..813] |
|
|
0.0 | [3..648] | [41..693] |
|
|
0.0 | [3..648] | [41..693] |
|
|
0.0 | [4..619] | [29..645] |
|
|
0.0 | [11..782] | [11..791] |
|
Region A: Residues: [1-126] |
1 11 21 31 41 51
| | | | | |
1 MKVRKYITLC FWWAFSTSAL VSSQQIPLKD HTSRQYFAVE SNETLSRLEE MHPNWKYEHD 60
61 VRGLPNHYVF SKELLKLGKR SSLEELQGDN NDHILSVHDL FPRNDLFKRL PVPAPPMDSS 120
121 LLPVKE
|
| Detection Method: |  |
| Confidence: | 12.154902 |
| Match: | 1kn6A_ |
| Description: | Prohormone convertase 1 pro-domain |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [127-465] |
1 11 21 31 41 51
| | | | | |
1 AEDKLSINDP LFERQWHLVN PSFPGSDINV LDLWYNNITG AGVVAAIVDD GLDYENEDLK 60
61 DNFCAEGSWD FNDNTNLPKP RLSDDYHGTR CAGEIAAKKG NNFCGVGVGY NAKISGIRIL 120
121 SGDITTEDEA ASLIYGLDVN DIYSCSWGPA DDGRHLQGPS DLVKKALVKG VTEGRDSKGA 180
181 IYVFASGNGG TRGDNCNYDG YTNSIYSITI GAIDHKDLHP PYSEGCSAVM AVTYSSGSGE 240
241 YIHSSDINGR CSNSHGGTSA AAPLAAGVYT LLLEANPNLT WRDVQYLSIL SAVGLEKNAD 300
301 GDWRDSAMGK KYSHRYGFGK IDAHKLIEMS KTWENVNAQ
|
| Detection Method: | |
| Confidence: | 145.08661 |
| Match: | 1meeA_ |
| Description: | Messentericopeptidase |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| nerve growth factor binding | 3.24561213884463 | bayes_pls_golite062009 |
| neurotrophin binding | 2.55889134368092 | bayes_pls_golite062009 |
| peptidase activity | 1.00880393712776 | bayes_pls_golite062009 |
| binding | 0.861331602166808 | bayes_pls_golite062009 |
| peptidase activity, acting on L-amino acid peptides | 0.786519779876448 | bayes_pls_golite062009 |
| catalytic activity | 0.597535457699629 | bayes_pls_golite062009 |
| endopeptidase activity | 0.498073926095918 | bayes_pls_golite062009 |
| hydrolase activity | 0.409855173053541 | bayes_pls_golite062009 |
| serine hydrolase activity | 0.163200450825161 | bayes_pls_golite062009 |
| serine-type peptidase activity | 0.151304815307398 | bayes_pls_golite062009 |
|
Region A: Residues: [466-611] |
1 11 21 31 41 51
| | | | | |
1 TWFYLPTLYV SQSTNSTEET LESVITISEK SLQDANFKRI EHVTVTVDID TEIRGTTTVD 60
61 LISPAGIISN LGVVRPRDVS SEGFKDWTFM SVAHWGENGV GDWKIKVKTT ENGHRIDFHS 120
121 WRLKLFGESI DSSKTETFVF GNDKEE
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [612-814] |
1 11 21 31 41 51
| | | | | |
1 VEPAATESTV SQYSASSTSI SISATSTSSI SIGVETSAIP QTTTASTDPD SDPNTPKKLS 60
61 SPRQAMHYFL TIFLIGATFL VLYFMFFMKS RRRIRRSRAE TYEFDIIDTD SEYDSTLDNG 120
121 TSGITEPEEV EDFDFDLSDE DHLASLSSSE NGDAEHTIDS VLTNENPFSD PIKQKFPNDA 180
181 NAESASNKLQ ELQPDVPPSS GRS
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
