YRC Public Data Repository - Protein Structure Prediction

Protein:	MRPL22
Organism:	Saccharomyces cerevisiae
Length:	309 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MRPL22.

Description	E-value	Query Range	Subject Range
MRPL22 - Mitochondrial ribosomal protein of the large subunit	0.0	[1..309]	[1..309]
RK22_PEA - 50S ribosomal protein L22, chloroplastic OS=Pisum sativum GN=rpl22 PE=2 SV=1	8.0E-46	[101..278]	[16..201]
gi\|31324951 - gi\|31324951\|gb\|AAH52940.1\| Rpl17 protein [Mus musculus] gi\|109122149, gi... - gi\|109122151\|ref\|XP_001089275.1\| PREDICTED: similar to 60S ribosomal protein L17 (L23) isoform 5 [Ma... gi\|114692313, gi... - gi\|55627436\|ref\|XP_518757.1\| PREDICTED: hypothetical protein isoform 3 [Pan troglodytes], gi\|1146923... gi\|73962160, gi\|... - gi\|73962164\|ref\|XP_861376.1\| PREDICTED: similar to 60S ribosomal protein L17 (L23) isoform 10 [Canis... RPL17 - ribosomal protein L17 ENSCJAT000000092... - null, null gi\|123982774, gi... - gi\|123997445\|gb\|ABM86324.1\| ribosomal protein L17 [synthetic construct], gi\|123982774\|gb\|ABM83128.1\|... RL17_FELCA - 60S ribosomal protein L17 OS=Felis catus GN=RPL17 PE=2 SV=3	5.0E-45	[155..282]	[7..165]
gi\|57682 - gi\|57682\|emb\|CAA41278.1\| ribosomal protein L17 [Rattus rattus] RL17_BOVIN - 60S ribosomal protein L17 OS=Bos taurus GN=RPL17 PE=2 SV=3 gi\|77415533, gi\|... - gi\|77415533\|gb\|AAI06166.1\| Ribosomal protein L17 [Mus musculus], gi\|62024644\|gb\|AAH92091.1\| Ribosoma... gi\|149720927 - gi\|149720927\|ref\|XP_001499165.1\| PREDICTED: similar to Rpl17 protein isoform 1 [Equus caballus] gi\|50806588, gi\|... - gi\|50806588\|ref\|XP_424454.1\| PREDICTED: similar to Rpl17 protein [Gallus gallus], gi\|118119614\|ref\|X... gi\|149463856 - gi\|149463856\|ref\|XP_001505494.1\| PREDICTED: similar to POU domain, class 6, transcription factor 2 [... gi\|55716080 - gb\|AAH86177.1\| Unknown (protein for MGC:98635) [Xenopus laevis] RL17_RAT - 60S ribosomal protein L17 OS=Rattus norvegicus GN=Rpl17 PE=2 SV=3 tr\|G3HMS8\|G3HMS8... - 60S ribosomal protein L17 OS=Cricetulus griseus GN=I79_012050 PE=3 SV=1 gi\|62548128, gi\|... - gi\|62548128\|gb\|AAX86695.1\| ribosomal protein L17 [Taeniopygia guttata], gi\|197127959\|gb\|ACH44457.1\| ... gi\|126320711 - gi\|126320711\|ref\|XP_001365329.1\| PREDICTED: similar to Rpl17 protein [Monodelphis domestica] tr\|G1SCJ6\|G1SCJ6... - pep:known chromosome:oryCun2:2:27709552:27710106:-1 gene:ENSOCUG00000022888 transcript:ENSOCUT000000... gi\|542163003\|ref... - PREDICTED: 60S ribosomal protein L17 [Zonotrichia albicollis]	9.0E-45	[155..282]	[7..165]
RL17_MOUSE - 60S ribosomal protein L17 OS=Mus musculus GN=Rpl17 PE=1 SV=3	9.0E-45	[155..282]	[7..165]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	1.0E-44	[124..299]	[217..397]
gi\|15293901 - gi\|15293901\|gb\|AAK95143.1\|AF401571_1 ribosomal protein L17 [Ictalurus punctatus]	2.0E-44	[155..280]	[7..163]
gi\|7340070 - gi\|7340070\|gb\|AAF61071.1\|AF220552_1 ribosomal protein L17 [Paralichthys olivaceus]	2.0E-44	[155..282]	[7..165]
gi\|110735706, gi... - gi\|21553938\|gb\|AAM63019.1\| unknown [Arabidopsis thaliana], gi\|18417177\|ref\|NP_567805.1\| ribosomal pr...	3.0E-44	[81..299]	[19..246]
RK22_NICSY - 50S ribosomal protein L22, chloroplastic OS=Nicotiana sylvestris GN=rpl22 PE=3 SV=1 RK22_TOBAC - 50S ribosomal protein L22, chloroplastic OS=Nicotiana tabacum GN=rpl22 PE=3 SV=1	3.0E-39	[157..307]	[3..152]

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Predicted Domain #1

Region A:
Residues: [1-124]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNFHTARISQ VGVISRALLS SVSRRWIHVT PISLNNSGGS LFGSITENKP KEGKNRGDED  60
   61 AGSFSNRLAI ASDSSGEAPE VNRDSITIEN DKLLQQHIIS LQQPEQLASQ SLLSPLKREI 120
  121 YEAN

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [125-309]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CKINGGFYKK DTIVKLPNSS ERYKLKFTKR EIEVLEPSVY AQSYRIKSSM KKATLLLRLL  60
   61 GGLDVMKAIS QCHFSNKKIA REVAELLQKG VKDGQKLGLK PEDLYISQIW TGSDGFWRKR 120
  121 VEFKARTRIG IISHPYIHVR CILRTKSVTK RRLAYEAHLK EQKRAPWVQL GDKPIRGVTG 180
  181 GVYKW

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	32.0
Match:	1lnrQ_
Description:	No description for 1lnrQ_ was found.

Predicted functions:

Term	Confidence	Notes
structural constituent of ribosome	9.71138472170121	bayes_pls_golite062009
structural molecule activity	9.13471776263155	bayes_pls_golite062009
binding	1.30630421512737	bayes_pls_golite062009
protein binding	0.592567938703741	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: