YRC Public Data Repository - Protein Structure Prediction

Protein:	ERR3
Organism:	Saccharomyces cerevisiae
Length:	437 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ERR3.

Description	E-value	Query Range	Subject Range
ENOA_CHICK - Alpha-enolase OS=Gallus gallus GN=ENO1 PE=2 SV=2	0.0	[1..435]	[1..432]
ENOA_ANAPL - Alpha-enolase OS=Anas platyrhynchos GN=ENO1 PE=2 SV=2	0.0	[1..435]	[1..432]
ENOA_ALLMI - Alpha-enolase OS=Alligator mississippiensis PE=2 SV=3	0.0	[1..435]	[1..432]
gi\|114552694 - gi\|114552694\|ref\|XP_514354.2\| PREDICTED: enolase 1 [Pan troglodytes] ENO1 - enolase 1, (alpha) gi\|123995887, gi... - gi\|61354812\|gb\|AAX41062.1\| enolase 1 [synthetic construct], gi\|60812591\|gb\|AAX36218.1\| enolase 1 [sy...	0.0	[1..434]	[1..431]
ENOA_TRASC - Alpha-enolase OS=Trachemys scripta PE=2 SV=3 ENOA_TRASE - Alpha-enolase OS=Trachemys scripta elegans PE=2 SV=3	0.0	[1..435]	[1..432]
ENOA_XENLA - Alpha-enolase OS=Xenopus laevis GN=eno1 PE=2 SV=2	0.0	[1..434]	[1..431]
gi\|120577448, gi... - gi\|147907170\|ref\|NP_001091239.1\| hypothetical protein LOC100037034 [Xenopus laevis], gi\|120577448\|gb... ENOA_MOUSE - Alpha-enolase OS=Mus musculus GN=Eno1 PE=1 SV=3	0.0	[1..434]	[1..431]

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Predicted Domain #1

Region A:
Residues: [1-127]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSITKVHART VYDSRGNPTV EVEITTENGL FRAIVPSGAS TGIHEAVELR DGNKSEWMGK  60
   61 GVTKAVSNVN SIIGPALIKS DLCVTNQKGI DELMISLDGT SNKSRLGANA ILGVSLCVAR 120
  121 AAAAQKG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	2800.0
Match:	1els__
Description:	Enolase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
phosphopyruvate hydratase activity	10.7545435133049	bayes_pls_golite062009
transcription regulator activity	2.33007926350873	bayes_pls_golite062009
nucleic acid binding	2.15117039251634	bayes_pls_golite062009
DNA binding	1.97129250063131	bayes_pls_golite062009
binding	1.95079397144714	bayes_pls_golite062009
intramolecular lyase activity	1.72552670956901	bayes_pls_golite062009
transcription repressor activity	1.36446664329679	bayes_pls_golite062009
transcription factor activity	1.24065454553451	bayes_pls_golite062009
lyase activity	0.953241510600178	bayes_pls_golite062009
carbon-oxygen lyase activity	0.908937887773213	bayes_pls_golite062009
hydro-lyase activity	0.874016693867333	bayes_pls_golite062009
catalytic activity	0.534516847146079	bayes_pls_golite062009
protein binding	0.476896736636797	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [128-437]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ITLYKYIAEL ADARQDPFVI PVPFFNVLNG GAHAGGSLAM QEFKIAPVGA QSFAEAMRMG  60
   61 SEVYHHLKIL AKEQYGPSAG NVGDEGGVAP DIDTAEDALD MIVKAINICG YEGRVKVGID 120
  121 SAPSVFYKDG KYDLNFKEPN SDPSHWLSPA QLAEYYHSLL KKYPIISLED PYAEDDWSSW 180
  181 SAFLKTVNVQ IIADDLTCTN KTRIARAIEE KCANTLLLKL NQIGTLTESI EAANQAFDAG 240
  241 WGVMISHRSG ETEDPFIADL VVGLRCGQIK SGALSRSERL AKYNELLRIE EELGDDCIYA 300
  301 GHRFHDGNKL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	2800.0
Match:	1els__
Description:	Enolase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: