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View Structure Prediction Details

Protein: GAS3
Organism: Saccharomyces cerevisiae
Length: 524 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GAS3.

Description E-value Query
Range
Subject
Range
gi|238881411 - gi|238881411|gb|EEQ45049.1| protein EPD2 precursor [Candida albicans WO-1]
gi|8132882 - gi|8132882|gb|AAF73430.1|AF247190_1 Phr1p [Candida albicans]
0.0 [3..486] [1..481]
gi|10441335 - gi|10441335|gb|AAG16995.1|AF184907_1 pH-regulated protein 1 [Candida dubliniensis]
0.0 [3..488] [1..483]
gi|18073453 - gi|18073453|emb|CAC83346.1| GAS-3 homologue [Candida glabrata]
0.0 [3..524] [1..536]
EPD1_CANMA - Protein EPD1 OS=Candida maltosa GN=EPD1 PE=3 SV=1
0.0 [3..489] [6..472]

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Predicted Domain #1
Region A:
Residues: [1-291]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQLSKSILLA ALAATPSLVN AMLPIHIKNY RFIKPSSATN SESDNEVFFV KGVDYQPGGS  60
   61 SGYDADSDTD ILSDPEVCAR DAYAFQQLGV NTVRIYSLNP DLNHDKCMTI FNNAGIYAIL 120
  121 DVNSGNYGES LNRADPSGTY DSLYLSRVFK FIDAFKNYPN VLGFFSGNEV INDQSDYAKI 180
  181 DPPYIRAVQR DMKQYISKHA NRSIPVGYSA ADNTDLRLAT FKYLQCNSLD GNKVNDDLDI 240
  241 SKSDFFGLNT YEWCSGTSSW ESSGYDKLNS TFEDAVIPLI FSEYGCNKNT P

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 14.52
Match: 1g01A
Description: Alkaline cellulase K catalytic domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrolase activity, acting on glycosyl bonds 2.54905777227767 bayes_pls_golite062009
hydrolase activity, hydrolyzing O-glycosyl compounds 2.53508565761702 bayes_pls_golite062009
hydrolase activity 1.83134281287223 bayes_pls_golite062009
catalytic activity 0.945396810092913 bayes_pls_golite062009
glucosidase activity 0.730759777713712 bayes_pls_golite062009
beta-glucosidase activity 0.465034466279462 bayes_pls_golite062009
chitinase activity 0.2746484616376 bayes_pls_golite062009
glucan 1,3-beta-glucosidase activity 0.148125357780819 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [292-368]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RTFDEVSEGL YGGLKNVFSG GLVYEYTEEA NNYGLVKLDD SGSLTYKDDF VNLESQLKNV  60
   61 SLPTTKESEI SSDSIYK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.774 d.93.1 SH2 domain
View Download 0.550 d.9.2 Description not found.
View Download 0.533 d.9.2 Description not found.
View Download 0.510 d.9.1 Interleukin 8-like chemokines
View Download 0.421 d.19.1 MHC antigen-recognition domain
View Download 0.376 d.50.1 dsRNA-binding domain-like
View Download 0.372 d.49.1 Signal recognition particle alu RNA binding heterodimer, SRP9/14
View Download 0.372 d.49.1 Signal recognition particle alu RNA binding heterodimer, SRP9/14
View Download 0.371 d.15.2 CAD & PB1 domains
View Download 0.366 a.77.1 DEATH domain
View Download 0.366 b.5.1 alpha-Amylase inhibitor tendamistat
View Download 0.335 d.16.1 FAD-linked reductases, C-terminal domain
View Download 0.330 g.44.1 RING/U-box
View Download 0.325 b.84.2 Rudiment single hybrid motif
View Download 0.325 d.10.1 DNA-binding domain
View Download 0.312 a.77.1 DEATH domain
View Download 0.290 b.1.18 E set domains
View Download 0.278 a.59.1 PAH2 domain
View Download 0.275 b.1.20 Tp47 lipoprotein, middle and C-terminal domains
View Download 0.275 d.129.1 TATA-box binding protein-like
View Download 0.271 b.1.2 Fibronectin type III
View Download 0.271 d.237.1 Hypothetical protein YjiA, C-terminal domain
View Download 0.268 d.9.1 Interleukin 8-like chemokines
View Download 0.256 b.1.2 Fibronectin type III
View Download 0.254 g.18.1 Complement control module/SCR domain
View Download 0.241 b.1.2 Fibronectin type III
View Download 0.237 a.150.1 Anti-sigma factor AsiA
View Download 0.229 d.50.2 Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain
View Download 0.225 b.1.2 Fibronectin type III
View Download 0.220 b.71.1 Glycosyl hydrolase domain
View Download 0.203 a.35.1 lambda repressor-like DNA-binding domains

Predicted Domain #3
Region A:
Residues: [369-524]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CDNSAITNIY SGFGTNNFTL PSQPAEIANM IEYGVNGTNT GKILTDYAVP TTFNYTIKNN  60
   61 KDDTISATIS YDKANSLNEL DVTATTVAKS ASTSQSSSRS LTSSTSPSSS TGSSSSTGSS 120
  121 SASSSSKSKG VGNIVNVSFS QSGYLALFAG LISALL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


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