YRC Public Data Repository - Protein Structure Prediction

Protein:	YMR209C
Organism:	Saccharomyces cerevisiae
Length:	457 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YMR209C.

Description	E-value	Query Range	Subject Range
YM59_YEAST - Uncharacterized protein YMR209C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YMR209C ... YMR209C - Putative S-adenosylmethionine-dependent methyltransferase; YMR209C is not an essential gene	0.0	[1..457]	[1..457]
gi\|12846470 - gi\|12846470\|dbj\|BAB27180.1\| unnamed protein product [Mus musculus]	0.0	[92..451]	[61..394]
CG11596-PC - This gene is referred to in FlyBase by the symbol Dmel\CG11596 (CG11596, FBgn0023522). It is a prote...	0.0	[93..451]	[39..390]
SPBC1778.07 - methyltransferase N2227 family CARME_SCHPO - Carnosine N-methyltransferase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPBC1778.07 ...	2.0E-98	[78..451]	[7..361]
gi\|32404762, gi\|... - gi\|32404762\|ref\|XP_322994.1\| hypothetical protein ( (AL451014) conserved hypothetical protein [Neuro... gi\|85103208 - gi\|85103208\|ref\|XP_961468.1\| hypothetical protein NCU03692 [Neurospora crassa OR74A]	1.0E-97	[125..451]	[8..342]
CE16654 - status:Confirmed UniProt:O62483 protein_id:CAB07703.1	1.0E-93	[92..447]	[23..360]
gi\|7494203 - pir\|\|T18435 hypothetical protein C0390w - malaria parasite (Plasmodium falciparum) gi\|16805183, gi\|... - gi\|3649764\|emb\|CAB11113.1\| N2227-like protein, putative [Plasmodium falciparum 3D7], gi\|16805183\|ref...	2.0E-87	[153..454]	[650..948]

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Predicted Domain #1

Region A:
Residues: [1-201]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVSSLASNII LALVVVLMTL LRQNKPLQRW FVSYVEKLLS RKSNLAQKVS VLSPSLKLVD  60
   61 VEKSISADQS NLSKINYQIP TLPDLTGNLI RLHEYRARGE GYNGLLFRRA RQLNGISEDQ 120
  121 LQKLGYFTKL MKNNEGIREN ARVIDKIIEF TLGKLIHSNE HDEEFTEEIE KICAEHGYKI 180
  181 KDGHLIQLNP DFVFPIVSSR G

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [202-457]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SQSVVHEALA HLCRDFSSYY SVERDPLQNF IISRINHHVI SAGDMKEKIL IVTPGAGVGG  60
   61 LSHTLATTFP KIQVDSIELS ALMYICNLFA LEYKHDVKIR PFVQQYSCQT VFDNQLRSLS 120
  121 ADLSKVGHRS NLDPLWGDFT RYSPISKDYD KIIICSAYFI DTAENMFEYL SSIEALKKYC 180
  181 KELHWVNVGP LKYGTKPLVQ FTGDELSRLR KIRGWKDLVE EYEVDSSKGL NGYLTDYESM 240
  241 YQGYYGLLKF HSVFES

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term	Confidence	Notes
S-adenosylmethionine-dependent methyltransferase activity	1.96327881369658	bayes_pls_golite062009
methyltransferase activity	1.90818766144575	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	1.84594628587396	bayes_pls_golite062009
rRNA methyltransferase activity	1.49245502333398	bayes_pls_golite062009
RNA methyltransferase activity	1.46179109169848	bayes_pls_golite062009
N-methyltransferase activity	0.920832355600944	bayes_pls_golite062009
catalytic activity	0.627101538772601	bayes_pls_golite062009
transferase activity	0.603160094615525	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: