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View Structure Prediction Details

Protein: ECM16
Organism: Saccharomyces cerevisiae
Length: 1267 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ECM16.

Description E-value Query
Range
Subject
Range
DHR1_YEAST - Probable ATP-dependent RNA helicase DHR1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN...
ECM16 - Essential DEAH-box ATP-dependent RNA helicase specific to the U3 snoRNP, predominantly nucleolar in ...
0.0 [1..1267] [1..1267]
SPAPB1A10.06c - ATP-dependent RNA helicase Dhr1
YK16_SCHPO - Putative ATP-dependent RNA helicase PB1A10.06c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843...
0.0 [1..1245] [1..1180]
DHX36_MOUSE - Probable ATP-dependent RNA helicase DHX36 OS=Mus musculus GN=Dhx36 PE=2 SV=1
0.0 [237..1232] [60..957]
DEXH4_ARATH - DExH-box ATP-dependent RNA helicase DExH4, chloroplastic OS=Arabidopsis thaliana GN=At1g58050 PE=3 S...
0.0 [6..1242] [173..1402]
gi|7959237 - gi|7959237|dbj|BAA96012.1| KIAA1488 protein [Homo sapiens]
0.0 [342..1232] [8..808]
gi|18087663, gi|... - gi|50918701|ref|XP_469747.1| putative helicase [Oryza sativa], gi|18087663|gb|AAL58955.1|AC091811_4 ...
0.0 [185..1251] [58..992]

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Predicted Domain #1
Region A:
Residues: [1-291]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGTYRKRFNE KARSGHMAKL KELKRIRNKQ FTRQDENDER VENPDSAPAE SSTTEPNANA  60
   61 EILEPLTEEE KKMKKRKLQE LFTPKESKVS RLKKKRLDKF IEHQLKREER KTIIGKLQDY 120
  121 KIDTSLLTSS KRLGEGRQTK KEEFKEALSL ERQGRGNEQT NEILYEEYEP KVWDEYGEGG 180
  181 SSEDDDGEDD FEASFGSMPK PTDNEEKKSS GFIDHRPAKF GGSGLSFGFS NIKVINKESK 240
  241 TPKKKYNWRQ RVEMEELKKH GKEDEMDFDT TSEDDDEEED QEEEDKMHPS E

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 47.30103
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [292-408]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NPLEEVESAD SETGSEKFDQ NDVANEFKDW ANQEIKKLEG RDQELVTPTL NIDYKPIIRK  60
   61 EDLDDGLQEA YVPINENSTR KAFYVEVSRS DEIQKARIQL PVFGEEHKIM EAIHHND

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [409-584]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VVIICGETGS GKTTQVPQFL YEAGFGAEDS PDYPGMVGIT QPRRVAAVSM AERVANELGD  60
   61 HGHKVGYQIR FDSTAKEDTK VKFMTDGVLL REMMHDFKLT KYSSIIIDEA HERNINTDIL 120
  121 IGMLSRCVRL RAKLHKENPI EHKKLKLIIM SATLRVSDFS ENKTLFPIAP PVLQVD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.221849
Match: 1hv8A_
Description: Putative DEAD box RNA helicase
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [585-695]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ARQFPVSIHF NRRTAFNYTD EAFRKTCKIH QKLPPGAILV FLTGQQEITH MVKRLRKEFP  60
   61 FKKNSKYNKD LETPVSKMGI NSKTTDLEAE DIDFSVQVID QDKFKSAIRY E

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.221849
Match: 1hv8A_
Description: Putative DEAD box RNA helicase
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [696-853]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EDEGNSGNGE DEEDEEEEGF EEVLTEGQTA NDPLYVLPLY SLLPTKEQMR VFQKPPQGSR  60
   61 LCIVATNVAE TSLTIPGVRY VVDSGRSKER KYNESNGVQS FEVGWVSKAS ANQRSGRAGR 120
  121 TGPGHCYRLY SSAVFEHDFE QFSKPEILRM PVESIVLQ

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 12.3
Match: 1fuuA
Description: Initiation factor 4a
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [854-1267]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKSMAIHNII NFPFPTPPDR VALSKAIQLL QYLGALDNKE MITEDGKKMS LFPLSPRFSK  60
   61 MLLVSDEKAC LPYIVAIVSA LSVGDPFINE FELGINEISR KPNPDENLDD KIREHDESTP 120
  121 GMDPELKKEL RSKFYKSRSQ FSKLDKFSDV FRLLSVVSAM DYVPKEQKEI FMKKNFLRGK 180
  181 LMEEIVKLRK QLMYIIKSNT SKENIAVVIR NEDLKSDIPS VIQIKLLKQM ICAGFVDHVA 240
  241 VRADVLFPDD AKITNRTSII NIPYIPVLAT RTPNIEDCFV YIHPTSILNN LGEMPPKYML 300
  301 YYSLHLGGNN KTRMNTLCDI ASTPLANIAR KGLLLTYSKP LTGQGLKTVN LSPTERYCYV 360
  361 VPRFGSTVDN DLKIGWDLNP IAVHQKKQKG QWTVIKFITR KGFQTITGEE KEKK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle