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View Structure Prediction Details

Protein: FAR8
Organism: Saccharomyces cerevisiae
Length: 523 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FAR8.

Description E-value Query
Range
Subject
Range
FAR8_YEAST - Factor arrest protein 8 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FAR8 PE=1 SV=1
FAR8 - Protein involved in recovery from cell cycle arrest in response to pheromone, in a Far1p-independent...
0.0 [1..523] [1..523]
SPBC1773.01 - striatin homolog
YGD1_SCHPO - Uncharacterized WD repeat-containing protein C1773.01 OS=Schizosaccharomyces pombe (strain 972 / ATC...
6.0E-33 [12..198] [22..262]
STRN3_RAT, STR3_RAT - Striatin-3 (Cell-cycle autoantigen SG2NA) (S/G2 antigen) (Fragment) - Rattus norvegicus (Rat), (P584...
6.0E-21 [11..71] [77..137]
STRN3_MOUSE - Striatin-3 OS=Mus musculus GN=Strn3 PE=1 SV=1
6.0E-21 [11..71] [62..122]
STRN3 - striatin, calmodulin binding protein 3
1.0E-19 [11..71] [62..122]

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Predicted Domain #1
Region A:
Residues: [1-120]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAINQAHVHP HYTLPGVMHY LQTEFTKNER DRITWELERS EMKARIAELE GENRDLKHQL  60
   61 NQIQSKAVSP EGEKEEKHVP DSLLQSKLAV QENVKEIIYL LKGPNTVNQL ESLNSREAGS 120
  121 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.782 N/A N/A a.47.2 t-snare proteins
View Download 0.782 N/A N/A a.47.2 t-snare proteins
View Download 0.689 N/A N/A a.47.2 t-snare proteins
View Download 0.619 N/A N/A a.24.4 Hemerythrin
View Download 0.619 N/A N/A a.24.4 Hemerythrin
View Download 0.607 N/A N/A a.47.2 t-snare proteins
View Download 0.530 N/A N/A a.29.3 Acyl-CoA dehydrogenase C-terminal domain-like
View Download 0.530 N/A N/A a.29.3 Acyl-CoA dehydrogenase C-terminal domain-like
View Download 0.485 N/A N/A a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.390 N/A N/A a.7.1 Spectrin repeat
View Download 0.380 N/A N/A a.7.1 Spectrin repeat
View Download 0.365 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.333 N/A N/A f.32.1 a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
View Download 0.311 N/A N/A a.2.11 Fe,Mn superoxide dismutase (SOD), N-terminal domain
View Download 0.298 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.294 N/A N/A a.48.1 N-terminal domain of cbl (N-cbl)
View Download 0.262 N/A N/A a.7.6 Ribosomal protein S20
View Download 0.259 N/A N/A a.24.17 Group V grass pollen allergen
View Download 0.248 N/A N/A a.7.4 Smac/diablo
View Download 0.245 N/A N/A a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.234 N/A N/A f.13.1 Family A G protein-coupled receptor-like
View Download 0.232 N/A N/A a.25.1 Ferritin-like
View Download 0.230 N/A N/A a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.227 N/A N/A a.24.11 Bacterial GAP domain
View Download 0.227 N/A N/A a.7.1 Spectrin repeat
View Download 0.227 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.226 N/A N/A a.60.8 HRDC-like
View Download 0.216 N/A N/A a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.214 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.211 N/A N/A a.126.1 Serum albumin-like
View Download 0.210 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.204 N/A N/A a.74.1 Cyclin-like

Predicted Domain #2
Region A:
Residues: [121-523]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ELHDLEKLNV NTPKEEGSAK TNGMDILNNA LLDTKPNPKQ GPSESPSPTK VKSLFSTANK  60
   61 RENNETISKI HSELSKVDII SSYGDCMALY DADTKSLEIH QVDANLNSKL LKKISLGQDS 120
  121 DIMKFFWVST SKLLVIEKSF HLKLFSISSA SLISDVDLLQ DSEQPFSSSD IINIDFKNKW 180
  181 LLIASKNKSQ IRIWELDNIE APEDVPINIK ETYEITHDND DDDSNDSTNI LDCILGITEK 240
  241 SLILLSSNPY QLTIYDFEGK LLQKIDLKID TILSGKPEEE GYHLFLDRKT SKLLIQLSNE 300
  301 RLLVYSFDKK KVVLKEQLTP SSTLPIQLDL NDSIITVSYS NGDFEFRNLE NLKPSIDEFV 360
  361 VADINFSERK EPVVFSSNLI VDSTPVLITV NKNNEVLLHK IKI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [203-523]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YGDCMALYDA DTKSLEIHQV DANLNSKLLK KISLGQDSDI MKFFWVSTSK LLVIEKSFHL  60
   61 KLFSISSASL ISDVDLLQDS EQPFSSSDII NIDFKNKWLL IASKNKSQIR IWELDNIEAP 120
  121 EDVPINIKET YEITHDNDDD DSNDSTNILD CILGITEKSL ILLSSNPYQL TIYDFEGKLL 180
  181 QKIDLKIDTI LSGKPEEEGY HLFLDRKTSK LLIQLSNERL LVYSFDKKKV VLKEQLTPSS 240
  241 TLPIQLDLND SIITVSYSNG DFEFRNLENL KPSIDEFVVA DINFSERKEP VVFSSNLIVD 300
  301 STPVLITVNK NNEVLLHKIK I

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 5.06
Match: 1erjA
Description: Tup1, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.92860449017551 bayes_pls_golite062009
protein binding 0.637100766251496 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle