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View Structure Prediction Details

Protein: ADI1
Organism: Saccharomyces cerevisiae
Length: 179 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ADI1.

Description E-value Query
Range
Subject
Range
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
5.0E-65 [1..176] [12..186]
MTND3_ARATH - 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 3 OS=Arabidopsis thaliana GN=ARD3 PE=2 SV=1
6.0E-65 [1..174] [12..184]
gi|14522834 - gi|14522834|dbj|BAB61039.1| iron-deficiency induced gene [Hordeum vulgare]
1.0E-64 [1..176] [12..186]
MTND_YEAST - 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase OS=Saccharomyces cerevisiae (strain ATCC 204508...
gi|151946169 - gi|151946169|gb|EDN64400.1| acireductone dioxygenease [Saccharomyces cerevisiae YJM789]
ADI1 - Acireductone dioxygenease involved in the methionine salvage pathway; ortholog of human MTCBP-1; tra...
gi|190408248 - gi|190408248|gb|EDV11513.1| acireductone Dioxygenease [Saccharomyces cerevisiae RM11-1a]
5.0E-64 [1..179] [1..179]
gi|208965780 - gi|208965780|dbj|BAG72904.1| acireductone dioxygenase 1 [synthetic construct]
ADI1 - acireductone dioxygenase 1
9.0E-63 [1..178] [1..177]

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Predicted Domain #1
Region A:
Residues: [1-70]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVKVYIHDNK VDSDYRAPHN SGTELSLDEL AKLGVIYKYC ANEEEVNEIA RQREYKNRDV  60
   61 VNICEGSFKS 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.346 0.918 nucleus a.4.1 Homeodomain-like
View Download 0.484 0.918 nucleus a.60.4 DNA repair protein Rad51, N-terminal domain
View Download 0.425 0.918 nucleus a.60.11 Hypothetical protein YjbJ
View Download 0.401 0.918 nucleus a.60.4 DNA repair protein Rad51, N-terminal domain
View Download 0.322 0.918 nucleus a.60.4 DNA repair protein Rad51, N-terminal domain
View Download 0.299 0.918 nucleus a.60.4 DNA repair protein Rad51, N-terminal domain
View Download 0.297 0.918 nucleus a.36.1 Signal peptide-binding domain
View Download 0.278 0.918 nucleus a.36.1 Signal peptide-binding domain
View Download 0.278 0.918 nucleus a.60.11 Hypothetical protein YjbJ
View Download 0.261 0.918 nucleus a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.259 0.918 nucleus a.36.1 Signal peptide-binding domain
View Download 0.240 0.918 nucleus a.36.1 Signal peptide-binding domain
View Download 0.239 0.918 nucleus a.4.1 Homeodomain-like
View Download 0.237 0.918 nucleus a.4.1 Homeodomain-like
View Download 0.228 0.918 nucleus a.4.1 Homeodomain-like
View Download 0.218 0.918 nucleus a.4.1 Homeodomain-like
View Download 0.214 0.918 nucleus a.74.1 Cyclin-like
View Download 0.212 0.918 nucleus a.60.4 DNA repair protein Rad51, N-terminal domain

Predicted functions:

Term Confidence Notes
binding 1.10919583483877 bayes_pls_golite062009
catalytic activity 0.401988496917198 bayes_pls_golite062009
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 0.262317442423345 bayes_pls_golite062009
protein binding 0.133891883527478 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [71-179]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EAEFNEKLAT FYQEHLHEDE EIRYCLEGAG YFDVRDASTP ENWIRCLVES GDLLILPPGI  60
   61 YHRFTLTTSN HIKALRLFKD EPKWQAINRS NQADSLPVRK DYIALINQY

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 8.62
Match: 1l3jA
Description: Oxalate decarboxylase YvrK
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle