YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: NGL3
Organism: Saccharomyces cerevisiae
Length: 505 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NGL3.

Description E-value Query
Range
Subject
Range
NGL3 - Putative endonuclease, has a domain similar to a magnesium-dependent endonuclease motif in mRNA dead...
gi|151946045 - gi|151946045|gb|EDN64276.1| conserved protein [Saccharomyces cerevisiae YJM789]
NGL3_YEAST - Probable RNA exonuclease NGL3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NGL3 PE=1 ...
0.0 [1..505] [1..505]
SPBC9B6.11c - CCR4 /nocturin family endoribonuclease
YNTB_SCHPO - Probable RNA exonuclease C9B6.11c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPBC9B6....
4.0E-84 [9..494] [30..501]
gi|17391192, gi|... - gi|21450299|ref|NP_659159.1| CCR4-NOT transcription complex, subunit 6-like isoform 1 [Mus musculus]...
gi|149046868, gi... - gi|157823321|ref|NP_001101825.1| CCR4-NOT transcription complex, subunit 6-like [Rattus norvegicus],...
1.0E-74 [68..491] [160..530]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
5.0E-73 [48..492] [194..666]
gi|6735375, gi|1... - gi|6735375|emb|CAB68196.1| putative protein [Arabidopsis thaliana], gi|15231075|ref|NP_191417.1| hyd...
2.0E-72 [17..493] [163..597]
gi|6330365 - gi|6330365|dbj|BAA86508.1| KIAA1194 protein [Homo sapiens]
2.0E-68 [62..494] [176..558]

Back

Predicted Domain #1
Region A:
Residues: [1-407]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSQVEGKIS PSQKESSSTS GLVSPSEDGP AHQKIHRDQL SVDQIKKIRE ERAQKRQVRR  60
   61 NSLISQGKDP DFPTPDLQFI ERPFLPINHD NSKGLTPATI QVTQDSLDVK IMTYNTLAQT 120
  121 LIRRDFFPES GPALKWHKRS KVLVHELKKY RPDVVSLQEV DYNELNFWQE NFHKLGFDVI 180
  181 FKRHEGKTHG LLVAWNNKKF QLDNDWMLDY DNILAGNVIS ARTRTKNIAL IISLYFKGIT 240
  241 DSSSRGIIVA NTHLFWHPFG VFERLRQSYL VLQKIQEIKA CSKYNGWHSL LMGDFNTEPE 300
  301 EPPYLAITKR PLILKGPIRA MVECSLAYRY SKKRNGEESD QDDEECDEKS RGEGHSDQPQ 360
  361 NPKPESFTAT KEEKALVNQL VALHNSLHVK GVSLYGIGYG KVHPENA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 50.0
Match: 1hd7A_
Description: DNA repair endonuclease Hap1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrolase activity, acting on ester bonds 1.79712722403488 bayes_pls_golite062009
catalytic activity 1.76511376991978 bayes_pls_golite062009
DNA binding 1.37658575624902 bayes_pls_golite062009
nuclease activity 1.32173587797854 bayes_pls_golite062009
nucleic acid binding 1.27522193028878 bayes_pls_golite062009
transcription regulator activity 1.27444635886918 bayes_pls_golite062009
hydrolase activity 1.26623219005539 bayes_pls_golite062009
binding 1.15309487870289 bayes_pls_golite062009
exonuclease activity 1.00241970456165 bayes_pls_golite062009
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 0.921825229691632 bayes_pls_golite062009
deoxyribonuclease activity 0.918937034405287 bayes_pls_golite062009
phosphoric ester hydrolase activity 0.483115797781113 bayes_pls_golite062009
phosphatase activity 0.384661571898828 bayes_pls_golite062009
protein binding 0.245431403492424 bayes_pls_golite062009
exodeoxyribonuclease activity 0.234646673057692 bayes_pls_golite062009
inositol or phosphatidylinositol phosphatase activity 0.228910502815798 bayes_pls_golite062009
exodeoxyribonuclease activity, producing 5'-phosphomonoesters 0.218294880470342 bayes_pls_golite062009
transcription activator activity 0.110687210838864 bayes_pls_golite062009
transcription cofactor activity 0.0749803326585898 bayes_pls_golite062009
transcription factor binding 0.0509794286384297 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [408-505]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NGSHGEPGLS NWANTWCGLL DYIFYIEGDH NQDTRQKEPL NAFEGNNNVK IIGYLRMPCA  60
   61 QEMPKHSQPF EGEYASDHIS LMCQIRLFFG GEKVHSLK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle