| Protein: | TCB3 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1545 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TCB3.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..1545] | [1..1545] |
|
|
0.0 | [56..1535] | [4..1442] |
|
|
0.0 | [66..1323] | [2..1223] |
|
|
0.0 | [215..1240] | [52..1087] |
|
|
0.0 | [215..1075] | [62..870] |
|
|
0.0 | [215..1075] | [20..838] |
|
|
0.0 | [215..1093] | [42..957] |
|
Region A: Residues: [1-360] |
1 11 21 31 41 51
| | | | | |
1 MTGIKAQVHP PPDSTLFHEE EKKKVGGNLP QKVINQQERG SDHAPSGHHQ YHQLINHDAN 60
61 DTKTSNSVSD VSKGQKTADS NPEGKKQSSK DIFVASSAQK TNQLPGPNPQ GSIGAVPLEG 120
121 LRPKEFRSAP SRKPNKFDTS ITKPGVLDDL GKLDEKDIKE KFHLDSDDKL FPWQNVGEFH 180
181 ASGKGSPNTK MSRVIKAYIL ENFYNDWYCN IATVLGTCFF SWLFAYIGFS WWSMIFIFLG 240
241 TATVYNAEYT RFNRNIRDDL KRVTVEETLS DRVESTTWLN SFLSKFWVIY MPVLSQQVKD 300
301 NVNPQLAGVA PGYGIDALAI DEFTLGSKAP TIKGIKSYTK TGKNTVEMDW SFAFTPSDVS 360
361
|
| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [361-481] |
1 11 21 31 41 51
| | | | | |
1 DMTATEAREK INPKISLGVT LGKSFVSKTM PILVEDINVA GKMRIKVEFG KAFPNIKIVS 60
61 LQLLEPPLID FALKPIGGDT LGLDVMSFLP GLKSFVKNII NSNIGPMLFP PNHLDINVED 120
121 I
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.606 | 0.120 | cellular bud | d.108.1 | Acyl-CoA N-acyltransferases (Nat) |
| View | Download | 0.540 | 0.034 | cellular bud | b.1.10 | Clathrin adaptor appendage domain |
| View | Download | 0.816 | 0.032 | cellular bud | b.61.1 | Avidin/streptavidin |
| View | Download | 0.654 | 0.010 | cellular bud | d.58.20 | NAD-binding domain of HMG-CoA reductase |
| View | Download | 0.549 | 0.004 | cellular bud | d.58.44 | Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains |
| View | Download | 0.523 | N/A | N/A | d.233.1 | Inhibitor of vertebrate lysozyme, Ivy |
| View | Download | 0.506 | N/A | N/A | d.20.1 | UBC-like |
| View | Download | 0.505 | N/A | N/A | d.109.1 | Actin depolymerizing proteins |
| View | Download | 0.456 | N/A | N/A | c.16.1 | Lumazine synthase |
| View | Download | 0.449 | N/A | N/A | a.24.3 | Cytochromes |
| View | Download | 0.440 | N/A | N/A | d.87.2 | CO dehydrogenase flavoprotein C-terminal domain-like |
| View | Download | 0.423 | N/A | N/A | d.14.1 | Ribosomal protein S5 domain 2-like |
| View | Download | 0.421 | N/A | N/A | b.1.10 | Clathrin adaptor appendage domain |
| View | Download | 0.415 | N/A | N/A | d.58.21 | Molybdenum cofactor biosynthesis protein C, MoaC |
| View | Download | 0.411 | N/A | N/A | d.101.1 | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 2 and 5 |
| View | Download | 0.404 | N/A | N/A | b.1.5 | Transglutaminase, two C-terminal domains |
| View | Download | 0.402 | N/A | N/A | a.24.11 | Bacterial GAP domain |
| View | Download | 0.398 | N/A | N/A | d.41.5 | Molybdopterin synthase subunit MoaE |
| View | Download | 0.383 | N/A | N/A | b.61.4 | Quinohemoprotein amine dehydrogenase A chain, domain 3 |
| View | Download | 0.374 | N/A | N/A | a.24.10 | Histidine-containing phosphotransfer domain, HPT domain |
| View | Download | 0.363 | N/A | N/A | b.71.1 | Glycosyl hydrolase domain |
| View | Download | 0.363 | N/A | N/A | d.201.1 | SRP19 |
| View | Download | 0.363 | N/A | N/A | d.105.1 | Clathrin adaptor appendage, alpha and beta chain-specific domain |
| View | Download | 0.361 | N/A | N/A | d.16.1 | FAD-linked reductases, C-terminal domain |
| View | Download | 0.361 | N/A | N/A | d.129.2 | Phosphoglucomutase, C-terminal domain |
| View | Download | 0.360 | N/A | N/A | d.52.7 | Ribosome-binding factor A, RbfA |
| View | Download | 0.356 | N/A | N/A | d.21.1 | Diaminopimelate epimerase-like |
| View | Download | 0.352 | N/A | N/A | b.1.10 | Clathrin adaptor appendage domain |
| View | Download | 0.344 | N/A | N/A | d.198.1 | Type III secretory system chaperone |
| View | Download | 0.337 | N/A | N/A | d.105.1 | Clathrin adaptor appendage, alpha and beta chain-specific domain |
| View | Download | 0.334 | N/A | N/A | d.14.1 | Ribosomal protein S5 domain 2-like |
| View | Download | 0.332 | N/A | N/A | a.29.3 | Acyl-CoA dehydrogenase C-terminal domain-like |
| View | Download | 0.312 | N/A | N/A | d.129.2 | Phosphoglucomutase, C-terminal domain |
| View | Download | 0.304 | N/A | N/A | d.20.1 | UBC-like |
| View | Download | 0.299 | N/A | N/A | b.18.1 | Galactose-binding domain-like |
| View | Download | 0.289 | N/A | N/A | d.141.1 | Ribosomal protein L6 |
| View | Download | 0.284 | N/A | N/A | a.118.9 | ENTH/VHS domain |
| View | Download | 0.277 | N/A | N/A | d.232.1 | Mago nashi protein |
| View | Download | 0.274 | N/A | N/A | c.2.1 | NAD(P)-binding Rossmann-fold domains |
| View | Download | 0.273 | N/A | N/A | d.19.1 | MHC antigen-recognition domain |
| View | Download | 0.272 | N/A | N/A | a.22.1 | Histone-fold |
| View | Download | 0.265 | N/A | N/A | d.129.3 | Bet v1-like |
| View | Download | 0.259 | N/A | N/A | d.68.1 | Translation initiation factor IF3, C-terminal domain |
| View | Download | 0.257 | N/A | N/A | d.101.1 | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 2 and 5 |
| View | Download | 0.251 | N/A | N/A | b.1.1 | Immunoglobulin |
| View | Download | 0.250 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.248 | N/A | N/A | d.56.1 | GroEL-intermediate domain like |
| View | Download | 0.247 | N/A | N/A | d.198.1 | Type III secretory system chaperone |
| View | Download | 0.241 | N/A | N/A | a.47.2 | t-snare proteins |
| View | Download | 0.239 | N/A | N/A | d.58.43 | Mechanosensitive channel protein MscS (YggB), C-terminal domain |
| View | Download | 0.238 | N/A | N/A | d.58.7 | RNA-binding domain, RBD |
| View | Download | 0.230 | N/A | N/A | d.108.1 | Acyl-CoA N-acyltransferases (Nat) |
| View | Download | 0.230 | N/A | N/A | c.47.2 | RNA 3'-terminal phosphate cyclase, RPTC, insert domain |
| View | Download | 0.228 | N/A | N/A | d.58.49 | YajQ-like |
| View | Download | 0.221 | N/A | N/A | d.129.1 | TATA-box binding protein-like |
| View | Download | 0.221 | N/A | N/A | c.2.1 | NAD(P)-binding Rossmann-fold domains |
| View | Download | 0.217 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.215 | N/A | N/A | b.60.1 | Lipocalins |
| View | Download | 0.203 | N/A | N/A | d.108.1 | Acyl-CoA N-acyltransferases (Nat) |
| View | Download | 0.202 | N/A | N/A | d.52.4 | YhbC-like, N-terminal domain |
| View | Download | 0.201 | N/A | N/A | b.60.1 | Lipocalins |
|
Region A: Residues: [482-633] |
1 11 21 31 41 51
| | | | | |
1 MAAQSKEAIG VLAVTIASAD SLKGSDFITN TVDPYIVMTT EDAVPGTDEE VRTSIKSNVK 60
61 NPRWNETKYL LLNTLEQKLN LKCFDFNDVR KDTVIGDLQL DLADLLQNPV LDNQTAELRS 120
121 GTKSKGILHY SLHWFPVKED KSEEKAVERA EA
|
| Detection Method: | |
| Confidence: | 94.502279 |
| Match: | 1rsy__ |
| Description: | Synaptogamin I |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [634-769] |
1 11 21 31 41 51
| | | | | |
1 KAKGKKEDEN EDTTEKEEDE NEESSQTDVG IAKITLQKVK YLDTTSSMTG SLSPCAELFI 60
61 DGQKVKSYRT LRRINEPSWN ETIEVLVPSK SNSKFVLKIF DDRMNGKALI CEYSSSLDDI 120
121 MTTLDTAQEF VKGSPQ
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.485 | 0.921 | cellular bud | d.110.1 | Profilin (actin-binding protein) |
| View | Download | 0.348 | 0.018 | cellular bud | b.60.1 | Lipocalins |
| View | Download | 0.423 | N/A | N/A | b.61.4 | Quinohemoprotein amine dehydrogenase A chain, domain 3 |
| View | Download | 0.408 | N/A | N/A | d.146.1 | Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain |
| View | Download | 0.332 | N/A | N/A | d.105.1 | Clathrin adaptor appendage, alpha and beta chain-specific domain |
| View | Download | 0.317 | N/A | N/A | c.57.1 | Molybdenum cofactor biosynthesis proteins |
| View | Download | 0.301 | N/A | N/A | c.51.2 | TolB, N-terminal domain |
| View | Download | 0.292 | N/A | N/A | b.111.1 | Small protein B (SmpB) |
| View | Download | 0.279 | N/A | N/A | d.24.1 | Pili subunits |
| View | Download | 0.254 | N/A | N/A | b.60.1 | Lipocalins |
| View | Download | 0.232 | N/A | N/A | b.55.1 | PH domain-like |
| View | Download | 0.228 | N/A | N/A | d.204.1 | Ribosome binding protein Y (YfiA homologue) |
| View | Download | 0.224 | N/A | N/A | b.55.1 | PH domain-like |
| View | Download | 0.224 | N/A | N/A | d.233.1 | Inhibitor of vertebrate lysozyme, Ivy |
| Term | Confidence | Notes |
| binding | 0.966987533854771 | bayes_pls_golite062009 |
| protein binding | 0.13127988530671 | bayes_pls_golite062009 |
|
Region A: Residues: [770-915] |
1 11 21 31 41 51
| | | | | |
1 GDIYLDVSWK SIEMTGAFAA ANSVSEPIGC IKLDVKDAII KGDLSGVGDV DPYYTVSLNR 60
61 RVLYKSIYHS DTDHPIFDNS TYVPIFSPNQ ILTLEFHDYQ KIGKDRFIGS VQIPTSNVFK 120
121 KDPKSGKYVG NNGKEEISKL KLKDHE
|
| Detection Method: | |
| Confidence: | 65.9897 |
| Match: | 1dsyA_ |
| Description: | C2 domain from protein kinase c (alpha) |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 0.966987533854771 | bayes_pls_golite062009 |
| protein binding | 0.13127988530671 | bayes_pls_golite062009 |
|
Region A: Residues: [916-979] |
1 11 21 31 41 51
| | | | | |
1 HKVTESIVNV STTFIPINLV YSPEELVNVE KLEKELKEKK KKFEATQEEN EQEMEKNPKE 60
61 WEVA
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.298 | d.15.7 | Immunoglobulin-binding domains |
| View | Download | 0.546 | b.84.2 | Rudiment single hybrid motif |
| View | Download | 0.608 | d.58.44 | Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains |
| View | Download | 0.352 | b.84.2 | Rudiment single hybrid motif |
| View | Download | 0.290 | a.2.3 | Chaperone J-domain |
| View | Download | 0.285 | a.22.1 | Histone-fold |
| View | Download | 0.274 | d.64.1 | eIF1-like |
| View | Download | 0.235 | b.1.2 | Fibronectin type III |
| View | Download | 0.226 | d.109.1 | Actin depolymerizing proteins |
| View | Download | 0.225 | a.64.1 | Saposin |
| View | Download | 0.215 | d.54.1 | Enolase N-terminal domain-like |
| View | Download | 0.213 | b.1.1 | Immunoglobulin |
| View | Download | 0.211 | d.16.1 | FAD-linked reductases, C-terminal domain |
| View | Download | 0.207 | d.109.1 | Actin depolymerizing proteins |
| Term | Confidence | Notes |
| binding | 0.966987533854771 | bayes_pls_golite062009 |
| protein binding | 0.13127988530671 | bayes_pls_golite062009 |
|
Region A: Residues: [980-1116] |
1 11 21 31 41 51
| | | | | |
1 EIEDPFDSDE KKINRKAKLS LNELIKQKSG ILSMQILEGT LSPSSAYLEI LADDISYPVF 60
61 ICMKPSQGKL NSEMANIFIR DLNYSKLHFR VSKKHIAKDS DDVISETSYS TLKLLKQAYE 120
121 EPMWLNFNGS KMKVRFL
|
| Detection Method: | |
| Confidence: | 149.503332 |
| Match: | 1dqvA_ |
| Description: | Synaptogamin I |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1117-1286] |
1 11 21 31 41 51
| | | | | |
1 YTPTSVKLPS SESVEDTGYL NIKLISGHGL KSADRNGYSD PFVHIFVNDK KVFKSNIKKK 60
61 TLDPVWNEDA KIPILSRSKN QVIFNVLDWD RAGDNDDLGQ ASLDVSSLEV GKTYNWNLNL 120
121 NTQGSIKLQG SFNPEYIKPS FDIVKGGITD KPMKIASGAA HATVGIAGTG
|
| Detection Method: | |
| Confidence: | 149.503332 |
| Match: | 1dqvA_ |
| Description: | Synaptogamin I |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1287-1402] |
1 11 21 31 41 51
| | | | | |
1 IGAATGVATG GLKKGGHLLK SLGGNPMKRS KSSNGNESNG AKKSSEKKSF DRRSPSNLNS 60
61 TSVTPRASLD YDPSVPNTSY APVQSASPVV KPTDNTSSSS NKKDTPSSNS RGHSRA
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [1403-1545] |
1 11 21 31 41 51
| | | | | |
1 SSFARTLAPH GTYNGFITVV AAENVAKHVQ IKISLTQGGR LKHIYKTKSQ KANNDGVAVF 60
61 DEECSFKASP EANLVLGAIS HQRLSRDKDL GIAQINLGDP QIQQDGQISV KLGDGHLIVK 120
121 INYGKDKNGQ VPPVPEVPQE YTQ
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.358 | 0.928 | cellular bud | d.110.1 | Profilin (actin-binding protein) |
| View | Download | 0.295 | 0.021 | cellular bud | b.60.1 | Lipocalins |
| View | Download | 0.586 | N/A | N/A | b.125.1 | Lipoprotein localization factors LolAB |
