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View Structure Prediction Details

Protein: DAK1
Organism: Saccharomyces cerevisiae
Length: 584 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DAK1.

Description E-value Query
Range		 Subject
Range
DAK1_YEAST - Dihydroxyacetone kinase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DAK1 PE=1 SV=1
DAK1 - Dihydroxyacetone kinase, required for detoxification of dihydroxyacetone (DHA); involved in stress a...
 0.0 [1..584] [1..584]
gi|10178999 - gi|10178999|emb|CAC08509.1| dihydroxyacetone kinase [Zygosaccharomyces rouxii]
 0.0 [1..583] [1..584]
DAK_PICAN - Dihydroxyacetone kinase OS=Pichia angusta GN=DAK PE=3 SV=1
DAK_PICAN - Dihydroxyacetone kinase OS=Pichia angusta GN=DAK PE=3 SV=1
 0.0 [1..583] [1..601]
gi|238032869, gi... - gi|254571923|ref|XP_002493071.1| Dihydroxyacetone kinase, required for detoxification of dihydroxyac...
DAK_PICPA - Dihydroxyacetone kinase OS=Komagataella pastoris GN=DAK PE=3 SV=1
jgi|Picpa1|39132... - null
 0.0 [1..583] [1..600]
DAK1_SCHPO - Dihydroxyacetone kinase 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=dak1 PE=3 SV=1
dak1 - dihydroxyacetone kinase Dak1
 0.0 [4..582] [3..580]
dak2 - dihydroxyacetone kinase Dak2
DAK2_SCHPO - Dihydroxyacetone kinase 2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=dak2 PE=3 SV=2
 0.0 [1..583] [1..588]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 0.0 [1..583] [1..588]
gi|15229519, gi|... - gi|71143068|gb|AAZ23925.1| At3g17770 [Arabidopsis thaliana], gi|15229519|ref|NP_188404.1| dihydroxya...
 0.0 [2..571] [4..574]

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Predicted Domain #1
Region A:
Residues: [1-352] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAKSFEVTD PVNSSLKGFA LANPSITLVP EEKILFRKTD SDKIALISGG GSGHEPTHAG  60
   61 FIGKGMLSGA VVGEIFASPS TKQILNAIRL VNENASGVLL IVKNYTGDVL HFGLSAERAR 120
  121 ALGINCRVAV IGDDVAVGRE KGGMVGRRAL AGTVLVHKIV GAFAEEYSSK YGLDGTAKVA 180
  181 KIINDNLVTI GSSLDHCKVP GRKFESELNE KQMELGMGIH NEPGVKVLDP IPSTEDLISK 240
  241 YMLPKLLDPN DKDRAFVKFD EDDEVVLLVN NLGGVSNFVI SSITSKTTDF LKENYNITPV 300
  301 QTIAGTLMTS FNGNGFSITL LNATKATKAL QSDFEEIKSV LDLLNAFTNA PG

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 9.94
Match: 1itwA
Description: Monomeric isocitrate dehydrogenase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
glycerone kinase activity 3.66907507772019 bayes_pls_golite062009
binding 0.69038000262198 bayes_pls_golite062009
catalytic activity 0.142389024724964 bayes_pls_golite062009
protein binding 0.133716715271428 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [353-584] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WPIADFEKTS APSVNDDLLH NEVTAKAVGT YDFDKFAEWM KSGAEQVIKS EPHITELDNQ  60
   61 VGDGDCGYTL VAGVKGITEN LDKLSKDSLS QAVAQISDFI EGSMGGTSGG LYSILLSGFS 120
  121 HGLIQVCKSK DEPVTKEIVA KSLGIALDTL YKYTKARKGS STMIDALEPF VKEFTASKDF 180
  181 NKAVKAAEEG AKSTATFEAK FGRASYVGDS SQVEDPGAVG LCEFLKGVQS AL

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 9.94
Match: 1itwA
Description: Monomeric isocitrate dehydrogenase
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle