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View Structure Prediction Details

Protein: SRC1
Organism: Saccharomyces cerevisiae
Length: 834 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SRC1.

Description E-value Query
Range
Subject
Range
SRC1_YEAST - Inner nuclear membrane protein SRC1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SRC1...
SRC1 - Inner nuclear membrane protein that functions in regulation of subtelomeric genes and is linked to T...
0.0 [1..834] [1..834]
mug61 - Sad1 interacting factor
MUG61_SCHPO - Meiotically up-regulated gene 61 protein OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=m...
0.0 [7..819] [6..836]
gi|6473492 - gi|6473492|dbj|BAA87142.1| Hypothetical protein [Schizosaccharomyces pombe]
2.0E-56 [619..818] [1..199]
gi|1160355 - gi|1160355|gb|AAB00542.1| UNC-89
5.0E-46 [15..449] [1339..1808]
gi|189442432 - gi|189442432|gb|AAI67864.1| LEM domain containing 3 [synthetic construct]
LEMD3 - LEM domain containing 3
8.0E-44 [679..820] [610..750]

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Predicted Domain #1
Region A:
Residues: [1-149]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSDLEYLED GFDPNSMKVA TLRRILVENN VDFPSNARKN ALVGLFDEKV KPQIPQLRKM  60
   61 YLNVRPSDEG IVKMDRPSSS PSIASPRRSR RARREKSASP MAKQFKKNRI LDDVSNDDDD 120
  121 DDDDDDDNDK KDDPLIVPSG TDTDEVDDE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [150-436]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EDDVITSSSN KSDTNDFQQN SDTRKKRKDP DSDDWSESNS KENKIDNKHL NLLSSDSEIE  60
   61 QDYQKAKKRK TSDLNQEHGN GSAILGKLSV KTPIKNTNRK PVSMDNFNDS LTSSGTENDP 120
  121 FVPNIRHNPK ELGTANGTGH STPLSKLKVS ASFADKLPQK EVPSTILVPE VEQQEPSQSE 180
  181 RTPSLFSSEG SGSESEAPLL PEITTPGPHQ PMGNTSNNVV EMIDTDSSNL VSDEDEVLVP 240
  241 TRIETPQLPT EKDVEKCEAR VQELQEEVNE QLEHENGSEF DVKQGSG

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.17
Match: 1iu4A
Description: Microbial transglutaminase
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [437-678]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KVGNRHKFKR ALKFLSKSLL ALFLFCIFIV IPLLFGLWYR EQRLLIGYCG HEVPSHRVSG  60
   61 NSFEFIQKLD NLLQDYRPKC IPCPPNGICY PYLKLKCKPD YKLAPSRLDF LEIIPAQGKC 120
  121 VKDDKKQQLV SEVVEKSLEF LRAKNAQISC GDGKDDIESG MTEDALYQIF NEARAPWIRD 180
  181 DEFEDLWIQV IKDLTEEPEI LWRQLSPTDN NIGGNSNNII KTNDVPRQKR HLPEKFISKT 240
  241 RN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [679-834]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FRSTSKKYIG MKCRFEREIY QTYKKFQRPI WLMFLLIVIS KVIEIKLKNY YRKKARIEEL  60
   61 VTQTMEKLKF QKIKSMSDPK ENAYLSIVQL RDIFLSDIVD LKYKNQLWSE VVKYLEHNNS 120
  121 NIKSNLTEIR GEIMKCWEWI GPMELNEPKD SAENKI

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.800 N/A N/A a.7.1 Spectrin repeat


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle