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View Structure Prediction Details

Protein: YLR446W
Organism: Saccharomyces cerevisiae
Length: 433 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YLR446W.

Description E-value Query
Range
Subject
Range
gi|15214423 - gi|15214423|gb|AAH12337.1| HKDC1 protein [Homo sapiens]
0.0 [6..433] [229..674]
HKDC1_MOUSE - Putative hexokinase HKDC1 OS=Mus musculus GN=Hkdc1 PE=2 SV=1
0.0 [6..431] [469..910]
HXK1_RAT - Hexokinase-1 OS=Rattus norvegicus GN=Hk1 PE=1 SV=4
0.0 [4..429] [467..911]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [5..429] [2..445]
gi|6840980 - gi|6840980|gb|AAF28854.1| hexokinase I [Cyprinus carpio]
0.0 [5..431] [126..571]

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Predicted Domain #1
Region A:
Residues: [1-433]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTIESTLARE LESLILPADS IVNVVDQFQE ELLSRLQTNT ISMLPQCLVP DKRSRWNPED  60
   61 KILTIDFGGT RLKFAIISLP QIVIEYNDAF ELTYNIVDSN FFNQIIYTIC TRLAANGYIK 120
  121 KKNESSEASK FFVSVTFSFP LNPEGEVVAM GKGFVMTDTL QGSTVKQLIQ SSFHRIISEN 180
  181 IEEFFCTMNV CHVINDAIAV SLTSKFICEN DSISLIIGTG TNACFEVPYG YLPPFKRDAL 240
  241 RETLPSSYNK ETLNFKHVLI NSEIGFIGKN VIALQPFDIH GAISYEMPLE CVTSGKWLPL 300
  301 SLKNILLQYN IIPKNFPVEF NGELVCQLAE DCTNAWFENE HYALICQIAR LLIKRAAFYV 360
  361 AAIVQAIDII TGCKNYNFIH IGYVGSFLHN SNFYREQIKY YSSIHIKLQF LNHSNLLGAA 420
  421 IATYLNKSDN QVQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 216.0
Match: 1bg3_B:1
Description: Mammalian type I hexokinase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.296484721581333 bayes_pls_golite062009
carbohydrate kinase activity 0.127155756785582 bayes_pls_golite062009
binding 0.067254720556817 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle