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View Structure Prediction Details

Protein: ATG23
Organism: Saccharomyces cerevisiae
Length: 453 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ATG23.

Description E-value Query
Range
Subject
Range
KRT84 - keratin 84
1.0E-94 [55..438] [144..508]
KRT84_MOUSE, K2H... - Keratin, type II cuticular Hb4 OS=Mus musculus GN=Krt84 PE=2 SV=1, (Q99M73) Keratin, type II cuticul...
3.0E-90 [55..450] [152..527]
K2M2_SHEEP - Keratin, type II microfibrillar, component 7C OS=Ovis aries PE=1 SV=1
8.0E-82 [55..435] [88..454]

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Predicted Domain #1
Region A:
Residues: [1-122]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MELNQVLEKK EQILQYLGTL VGLHEKALSD VNSASQVTSI RKDITICLND LCRINDLLVS  60
   61 HDGLLKREIG SLLRDKQELL ELNEREQLLW KERKSWHIKQ ETDAAPADYV IDKDAIITIS 120
  121 SH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 22.09691
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [123-261]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HRTSLNKYIE SVGAENTILS NTDDSDAMIE EVQNAESSAD QMIRNYKLLQ LSHKQAKSEI  60
   61 IRLETLLRDF KKDNKFIEEE LKRQSGRIRS EMGNIDFHLS KIEESKHQLM KRIGFESPLT 120
  121 QEKSLSEKIF NLRLSSADE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.939 0.760 autophagy a.47.2 t-snare proteins

Predicted Domain #3
Region A:
Residues: [262-453]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DYNERQTINM KNFVHMKDLI ELKIEDLQEQ LMRNKNESST VLTQRELWLD CQKKVGDLES  60
   61 KLITKLRSSS NSKIPPNEMS EMINSTIQYL NNLLDSSDEK LTTTLISNER DVLSKACEEL 120
  121 HSESTTAQDG SSALPSKPID IHKSHKGSNA SSNLKQPSTP SFLVASKSPP KIGISESVVN 180
  181 ANKNDAISKK VE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.522879
Match: 1gk4A_
Description: Vimentin coil
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle