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View Structure Prediction Details

Protein: YLR422W
Organism: Saccharomyces cerevisiae
Length: 1932 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YLR422W.

Description E-value Query
Range
Subject
Range
YLR422W - Protein of unknown function with similarity to human DOCK proteins (guanine nucleotide exchange fact...
YL422_YEAST - DOCK-like protein YLR422W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YLR422W PE=1 S...
0.0 [1..1932] [1..1932]
gi|2224539 - gi|2224539|dbj|BAA20759.1| KIAA0299 [Homo sapiens]
0.0 [1109..1862] [823..1551]
mbc-PA - The gene myoblast city is referred to in FlyBase by the symbol Dmel\mbc (CG10379, FBgn0015513). It i...
0.0 [1108..1872] [958..1703]
DOCK2_MOUSE, DOC... - Dedicator of cytokinesis protein 2 OS=Mus musculus GN=Dock2 PE=1 SV=2, (Q8C3J5) Dedicator of cytokin...
0.0 [1109..1871] [937..1666]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [1132..1850] [1..722]

Back

Predicted Domain #1
Region A:
Residues: [1-1253]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQQDSQRWL PTDRLIYGVL VKSFLPLQRY PELVYENSNY ANVYVGAEVY VFEESVDKKW  60
   61 CRAYQCLRPF PEEFISNMNS ANDVLPDVKP KVVIFPRKYV HFEAEKAVST MPFFKAPSAE 120
  121 DFKPLISKEC ESRSFCDSLY VSSTDDISTG KPRKTPRPPF PFFRYQKRSF KDEMGPILSL 180
  181 ISSHVYSMYS IGEFSIYRKM IKLYYDLDTI RFRLSMNLTT EAEKINLIRA ATSLRTKIAK 240
  241 FLSSTYRKNK LIANSTPRNP DPYGFEGIFA RDIDTGELLS YEIDKLRTLV SSSMLCGLTN 300
  301 NFPTVPVVES DDESSSNGLF GTVRSSILVN LKDLAWDPSI SDPKYQDLSI CVYLRTKDEV 360
  361 LTESFTMTKS SNMESALDEI PAMLFKNILE TIVHKNKVYL VVVLKETIAI TTETAPEISS 420
  421 YNISTEESSS HSPFSPFNSS TENKIDHVKK GLAAGVINIS PVFKFYNGLS VANKAQRFNL 480
  481 YLYSSDSSDS QNFNSSKDAD LGWGGLINKI IKDSSEGVSV NPRAVSLSVT VKEIIGKQEA 540
  541 EKVLSTSLVP IRSIPTYFYD TMFSQAERIY LNLGRVSLYG LPAADTNIEN VTVQISCRNK 600
  601 AVKFCKNKLE ERSGDWKFVS VRPNESIGES IRIEGVENMN EDETLRVLVY LNGFLMAKSN 660
  661 IHIKKKNEII EYRKGTVFQI MSSKSVPLIH LELEASYFGR RYNINPAITN FLVLQTKNVE 720
  721 FDQQLKEHYS VTLKQLNNVS FKDLLKHFDT ILAHYLLLLE SVNEATDKKG PSSSLPNIVF 780
  781 SEFVKFLNLM LTHQENSRYW FNRLYKKVMS KELECPNVAP ILIKHMTTIF DRSHSSWTRT 840
  841 GTAICRTILY IIVLAIGSSH SDEMPNFSHF FRSLHKFLML ADEPIMADQI LLIESIPSML 900
  901 ETMTNHCKVE DLVRFAIGLF ECCQEKEMNQ KMYSRPLSVR EEEYLNTKFN CLLKLINKKV 960
  961 LQNYLTNTES VDKLRLQFLS KTLEWLLTPY TPGDDKCFHV ESLRLVNSVF ITIIEDYKFD1020
 1021 MLQRNLIRLL PYLCKSFVHL RRYCKKARLM RPRRVFTMLF PREIPCNYIP VDSIVNDEVV1080
 1081 VEVLLELAII ICEITKIASS RFPSYQSFSE IINLCDKDTL FQSNFYSRQI TNENVYTITK1140
 1141 TVFLFFKQDW FPGMKWLGVS ALLGRSSLIL LSLCKDYIIE NNSPSPSKES EKRVDMRLWA1200
 1201 EYVKVILLVS NHKSASLTKL AITPRKAVYL ISGDLKKISA YILNECWDAL ATG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
protein binding 1.52511960414654 bayes_pls_golite062009
binding 1.26123458430912 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [1254-1856]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HYNITYAKKY GLGALSDCQF ELFVHNQFLI REIFIFAFHR HIDATRICCK ILWGLGLNFW  60
   61 RIFGSLQPAV NACIPELFSA YQIGKLRLND YELERFVSCL FFMMHVPDSD TFFPACMDFL 120
  121 RDLLGFLHIV NEIYKIPNQE EFDDDRTARH IEMFEYLLEA NRPELFHKMI YDLFIHFIQK 180
  181 KDFVQAALSL ELLAGTYAWD SNDTLEAISF PPLPEQSSFE RKEYLLKESA RNFSRGQKPE 240
  241 KALAVYKDLI KAYDEINYDL NGLAFVHDQI AGIYTRLQSI DRLVPTYFKV SFMGFGFPKS 300
  301 LRNKSFVFEG LPFEHITSMH DRLLRSYHGS NIVHSQEEVD MLLMNPPMGK YIHVASVEPC 360
  361 LSISDNYNSS DKKSSINNKV RMYIENRDLR TFSNSRRLPG AKGVTDLWVE EYTYHTMNTF 420
  421 PTLMNRSEIV KVTKSKLSPL ENAIRSLQVK IQELYGLENM CNKTLKDHGD VNDLFTELST 480
  481 NITGTISAPV NGGISQYKAF LEPSTSKQFS TDDLGRLTLA FDELVAVLGR CLTLHAELLP 540
  541 SKDLKPSHDL LVRLFEENFA EEIERYSRTL SEANRSRNNM ITARIISHKN PNKKASFSGR 600
  601 DHH

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [1857-1932]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TSGSNHSQFV LEHSDSFGPN SLLFGKYLTR TLSHSSTTSS LDKSGIVSGT SSTFLAGSQP  60
   61 NTNTDSQHKH DYSHSG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [435-498]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPFNSSTENK IDHVKKGLAA GVINISPVFK FYNGLSVANK AQRFNLYLYS SDSSDSQNFN  60
   61 SSKD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [499-586]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ADLGWGGLIN KIIKDSSEGV SVNPRAVSLS VTVKEIIGKQ EAEKVLSTSL VPIRSIPTYF  60
   61 YDTMFSQAER IYLNLGRVSL YGLPAADT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [587-770]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NIENVTVQIS CRNKAVKFCK NKLEERSGDW KFVSVRPNES IGESIRIEGV ENMNEDETLR  60
   61 VLVYLNGFLM AKSNIHIKKK NEIIEYRKGT VFQIMSSKSV PLIHLELEAS YFGRRYNINP 120
  121 AITNFLVLQT KNVEFDQQLK EHYSVTLKQL NNVSFKDLLK HFDTILAHYL LLLESVNEAT 180
  181 DKKG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [771-987]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSSSLPNIVF SEFVKFLNLM LTHQENSRYW FNRLYKKVMS KELECPNVAP ILIKHMTTIF  60
   61 DRSHSSWTRT GTAICRTILY IIVLAIGSSH SDEMPNFSHF FRSLHKFLML ADEPIMADQI 120
  121 LLIESIPSML ETMTNHCKVE DLVRFAIGLF ECCQEKEMNQ KMYSRPLSVR EEEYLNTKFN 180
  181 CLLKLINKKV LQNYLTNTES VDKLRLQFLS KTLEWLL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #8
Region A:
Residues: [988-1101]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPYTPGDDKC FHVESLRLVN SVFITIIEDY KFDMLQRNLI RLLPYLCKSF VHLRRYCKKA  60
   61 RLMRPRRVFT MLFPREIPCN YIPVDSIVND EVVVEVLLEL AIIICEITKI ASSR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #9
Region A:
Residues: [1102-1165]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FPSYQSFSEI INLCDKDTLF QSNFYSRQIT NENVYTITKT VFLFFKQDWF PGMKWLGVSA  60
   61 LLGR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #10
Region A:
Residues: [1166-1269]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSLILLSLCK DYIIENNSPS PSKESEKRVD MRLWAEYVKV ILLVSNHKSA SLTKLAITPR  60
   61 KAVYLISGDL KKISAYILNE CWDALATGHY NITYAKKYGL GALS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #11
Region A:
Residues: [1270-1307]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DCQFELFVHN QFLIREIFIF AFHRHIDATR ICCKILWG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #12
Region A:
Residues: [1308-1395]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LGLNFWRIFG SLQPAVNACI PELFSAYQIG KLRLNDYELE RFVSCLFFMM HVPDSDTFFP  60
   61 ACMDFLRDLL GFLHIVNEIY KIPNQEEF

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #13
Region A:
Residues: [1396-1468]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DDDRTARHIE MFEYLLEANR PELFHKMIYD LFIHFIQKKD FVQAALSLEL LAGTYAWDSN  60
   61 DTLEAISFPP LPE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #14
Region A:
Residues: [1469-1533]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QSSFERKEYL LKESARNFSR GQKPEKALAV YKDLIKAYDE INYDLNGLAF VHDQIAGIYT  60
   61 RLQSI

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #15
Region A:
Residues: [1534-1626]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DRLVPTYFKV SFMGFGFPKS LRNKSFVFEG LPFEHITSMH DRLLRSYHGS NIVHSQEEVD  60
   61 MLLMNPPMGK YIHVASVEPC LSISDNYNSS DKK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #16
Region A:
Residues: [1627-1691]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSINNKVRMY IENRDLRTFS NSRRLPGAKG VTDLWVEEYT YHTMNTFPTL MNRSEIVKVT  60
   61 KSKLS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #17
Region A:
Residues: [1692-1846]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLENAIRSLQ VKIQELYGLE NMCNKTLKDH GDVNDLFTEL STNITGTISA PVNGGISQYK  60
   61 AFLEPSTSKQ FSTDDLGRLT LAFDELVAVL GRCLTLHAEL LPSKDLKPSH DLLVRLFEEN 120
  121 FAEEIERYSR TLSEANRSRN NMITARIISH KNPNK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #18
Region A:
Residues: [1847-1932]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KASFSGRDHH TSGSNHSQFV LEHSDSFGPN SLLFGKYLTR TLSHSSTTSS LDKSGIVSGT  60
   61 SSTFLAGSQP NTNTDSQHKH DYSHSG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle