| Protein: | PDR8 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 701 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PDR8.
| Description | E-value | Query Range |
Subject Range |
|
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0.0 | [1..701] | [1..701] |
|
|
2.0E-75 | [8..499] | [1..519] |
|
|
2.0E-73 | [29..563] | [5..545] |
|
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2.0E-72 | [8..499] | [1..516] |
|
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5.0E-70 | [8..499] | [1..521] |
|
|
8.0E-66 | [8..497] | [1..537] |
|
Region A: Residues: [1-101] |
1 11 21 31 41 51
| | | | | |
1 MDGSHFPMKS TTGEPVSSGK KGKRRKVIKS CAFCRKRKLK CSQARPMCQQ CVIRKLPQCV 60
61 YTEEFNYPLS NTELFEQVPN VALVQKIENL QTLLKENDNN N
|
| Detection Method: |  |
| Confidence: | 68.67837 |
| Match: | 1hwtD_ |
| Description: | Hap1 (Cyp1); HAP1 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 4.56444258780502 | bayes_pls_golite062009 |
| DNA binding | 4.26146437716972 | bayes_pls_golite062009 |
| nucleic acid binding | 4.17369933547911 | bayes_pls_golite062009 |
| transcription factor activity | 3.049435548132 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 2.98081393153291 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.93914501897006 | bayes_pls_golite062009 |
| binding | 2.91929847152301 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 2.44382866473054 | bayes_pls_golite062009 |
| transcription activator activity | 2.24483536326713 | bayes_pls_golite062009 |
|
Region A: Residues: [102-169] |
1 11 21 31 41 51
| | | | | |
1 AKPVYCRSSE NPLRSLRTSV LGDNGSRYVF GPTSWKTLSL FEQNKFQTEF QNLWKVLKPL 60
61 PECTKSQL
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.538 | a.37.1 | A DNA-binding domain in eukaryotic transcription factors |
| View | Download | 0.534 | a.60.4 | DNA repair protein Rad51, N-terminal domain |
| View | Download | 0.540 | d.57.1 | DNA damage-inducible protein DinI |
| View | Download | 0.504 | d.58.49 | YajQ-like |
| View | Download | 0.683 | a.29.2 | Bromodomain |
| View | Download | 0.537 | a.77.1 | DEATH domain |
| View | Download | 0.523 | a.58.1 | Chemotaxis receptor methyltransferase CheR, N-terminal domain |
| View | Download | 0.505 | a.64.1 | Saposin |
| View | Download | 0.491 | a.60.11 | Hypothetical protein YjbJ |
| View | Download | 0.488 | a.60.1 | SAM/Pointed domain |
| View | Download | 0.487 | a.60.1 | SAM/Pointed domain |
| View | Download | 0.479 | d.58.24 | CheY-binding domain of CheA |
| View | Download | 0.458 | a.130.1 | Chorismate mutase II |
| View | Download | 0.422 | a.2.2 | Ribosomal protein L29 (L29p) |
| View | Download | 0.422 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.421 | d.58.8 | Viral DNA-binding domain |
| View | Download | 0.419 | d.58.17 | Metal-binding domain |
| View | Download | 0.412 | a.60.3 | C-terminal domain of RNA polymerase alpha subunit |
| View | Download | 0.382 | d.58.38 | Urease metallochaperone UreE, C-terminal domain |
| View | Download | 0.365 | d.52.1 | Alpha-lytic protease prodomain |
| View | Download | 0.361 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.360 | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.353 | d.58.3 | Protease propeptides/inhibitors |
| View | Download | 0.348 | d.58.17 | Metal-binding domain |
| View | Download | 0.323 | d.51.1 | Eukaryotic type KH-domain (KH-domain type I) |
| View | Download | 0.314 | d.58.10 | Acylphosphatase-like |
| View | Download | 0.300 | d.58.36 | Sulfite reductase, domains 1 and 3 |
| View | Download | 0.291 | d.58.5 | GlnB-like |
| View | Download | 0.279 | d.40.1 | CI-2 family of serine protease inhibitors |
| View | Download | 0.278 | a.4.6 | C-terminal effector domain of the bipartite response regulators |
| View | Download | 0.278 | g.50.1 | FYVE/PHD zinc finger |
| View | Download | 0.277 | a.2.9 | C-terminal UvrC-binding domain of UvrB |
| View | Download | 0.266 | d.94.1 | HPr-like |
| View | Download | 0.256 | d.58.49 | YajQ-like |
| View | Download | 0.254 | d.52.5 | Probable GTPase Der, C-terminal domain |
| View | Download | 0.249 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.239 | d.58.7 | RNA-binding domain, RBD |
| View | Download | 0.236 | d.129.1 | TATA-box binding protein-like |
| View | Download | 0.235 | d.58.14 | Ribosomal protein S6 |
| View | Download | 0.231 | d.58.11 | EF-G/eEF-2 domains III and V |
| View | Download | 0.227 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.225 | d.58.44 | Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains |
| View | Download | 0.221 | a.74.1 | Cyclin-like |
| View | Download | 0.219 | a.2.3 | Chaperone J-domain |
| View | Download | 0.218 | d.192.1 | YlxR-like |
| View | Download | 0.202 | d.58.18 | Regulatory domain in the aminoacid metabolism |
| View | Download | 0.201 | d.58.48 | MTH1187-like |
|
Region A: Residues: [170-446] |
1 11 21 31 41 51
| | | | | |
1 NENDVVADLP SFPQMESCIK SFFAGPLFGI LHIFNQDDIL SLLDRLFIRD TTDKNLVILL 60
61 DLQGNAKDKY NLGIVLQILC LGYYNQDIPS SVSHFLHTLS AASLSSSSSN FVEKLQFFLL 120
121 SYISVMINCT DGVWDATQGV DLINELCQGC ISLGLNDIDK WYLNESEETK QNLRCIWFWA 180
181 LFLDVSTSYD IGNPPSISDD LLDLSIFTAQ NFQSPSIDFR RVKLMHDFLD VSRFTTREIH 240
241 KREMNEKLTT FSLRLIEFIQ SNFSPIEHYT NSVYYSD
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| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [447-507] |
1 11 21 31 41 51
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1 IDPFDILILS RSLSIVASIY NIEMIIAQQS RIIDKNRMVQ FLLISISVCV NTMVFHFKEP 60
61 I
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| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.664 | a.144.1 | PABC (PABP) domain |
| View | Download | 0.665 | a.30.1 | ROP protein |
| View | Download | 0.623 | a.108.1 | Ribosomal protein L7/12, oligomerisation (N-terminal) domain |
| View | Download | 0.634 | a.30.2 | Homodimeric domain of signal transducing histidine kinase |
| View | Download | 0.623 | d.222.1 | YbaB-like |
| View | Download | 0.936 | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
| View | Download | 0.867 | a.29.3 | Acyl-CoA dehydrogenase C-terminal domain-like |
| View | Download | 0.671 | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.647 | a.7.5 | Tubulin chaperone cofactor A |
| View | Download | 0.642 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.578 | a.2.10 | Epsilon subunit of F1F0-ATP synthase C-terminal domain |
| View | Download | 0.542 | a.2.7 | tRNA-binding arm |
| View | Download | 0.530 | a.55.1 | IHF-like DNA-binding proteins |
| View | Download | 0.517 | a.2.8 | Eukaryotic DNA topoisomerase I, dispensable insert domain |
| View | Download | 0.487 | a.2.9 | C-terminal UvrC-binding domain of UvrB |
| View | Download | 0.485 | a.4.11 | RNA polymerase subunit RPB10 |
| View | Download | 0.474 | a.4.1 | Homeodomain-like |
| View | Download | 0.447 | a.144.2 | Ribosomal protein L20 |
| View | Download | 0.433 | a.4.1 | Homeodomain-like |
| View | Download | 0.422 | f.13.1 | Family A G protein-coupled receptor-like |
| View | Download | 0.419 | d.80.1 | Tautomerase/MIF |
| View | Download | 0.408 | a.16.1 | S15/NS1 RNA-binding domain |
| View | Download | 0.399 | d.48.1 | RecA protein, C-terminal domain |
| View | Download | 0.384 | a.74.1 | Cyclin-like |
| View | Download | 0.365 | d.43.1 | Elongation factor Ts (EF-Ts), dimerisation domain |
| View | Download | 0.359 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.355 | a.4.1 | Homeodomain-like |
| View | Download | 0.345 | d.58.23 | Probable ACP-binding domain of malonyl-CoA ACP transacylase |
| View | Download | 0.341 | a.156.1 | S13-like H2TH domain |
| View | Download | 0.337 | a.159.2 | FF domain |
| View | Download | 0.332 | a.16.1 | S15/NS1 RNA-binding domain |
| View | Download | 0.328 | a.32.1 | Transcription factor IIA (TFIIA), alpha-helical domain |
| View | Download | 0.324 | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.298 | a.6.1 | Putative DNA-binding domain |
| View | Download | 0.292 | a.64.2 | Bacteriocin AS-48 |
| View | Download | 0.285 | d.58.17 | Metal-binding domain |
| View | Download | 0.284 | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.283 | a.28.3 | Retrovirus capsid protein C-terminal domain |
| View | Download | 0.272 | a.4.9 | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 |
| View | Download | 0.270 | a.50.1 | Anaphylotoxins (complement system) |
| View | Download | 0.270 | a.112.1 | Description not found. |
| View | Download | 0.269 | g.57.1 | Serine proteinase inhibitor lekti |
| View | Download | 0.266 | a.21.1 | HMG-box |
| View | Download | 0.264 | a.59.1 | PAH2 domain |
| View | Download | 0.259 | a.2.2 | Ribosomal protein L29 (L29p) |
| View | Download | 0.259 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.254 | a.60.3 | C-terminal domain of RNA polymerase alpha subunit |
| View | Download | 0.252 | a.118.8 | TPR-like |
| View | Download | 0.251 | a.46.2 | Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain |
| View | Download | 0.240 | a.2.6 | Effector domain of the protein kinase pkn/prk1 |
| View | Download | 0.231 | a.4.1 | Homeodomain-like |
| View | Download | 0.230 | a.2.1 | GreA transcript cleavage protein, N-terminal domain |
| View | Download | 0.230 | a.140.1 | LEM domain |
| View | Download | 0.221 | f.15.1 | Small-conductance potassium channel |
| View | Download | 0.219 | g.58.1 | Pheromone ER-23 |
| View | Download | 0.215 | a.140.3 | Rho termination factor, N-terminal domain |
| View | Download | 0.214 | a.56.1 | CO dehydrogenase ISP C-domain like |
| View | Download | 0.209 | a.64.1 | Saposin |
| View | Download | 0.206 | a.5.6 | Hypothetical protein MTH1615 |
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Region A: Residues: [508-701] |
1 11 21 31 41 51
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1 NDQENVLTEG LKLSIILINP LLIRIVSQVY SLAFNRLIFR EKAFLFLIDL DTGKKIQFIK 60
61 YEEENFDELL TGFDVRTDKF LSFSGTIIRF YEIIDSIFAV NERNKRLLKA VSNFYQLTST 120
121 LAFERVSRVL FDKASQARIE TEKIWLKKGI NMEHFSDLMI EDFINDVWKT FKEISKDLWS 180
181 IDKKKFYKQY HFDL
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
