YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: HAP1
Organism: Saccharomyces cerevisiae
Length: 1502 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HAP1.

Description E-value Query
Range
Subject
Range
gi|171646 - gi|171646|gb|AAA34662.1| activator protein HAP1
0.0 [1..1471] [1..1471]
gi|18376230 - gi|18376230|emb|CAD21345.1| related to nitrate assimilation regulatory protein nirA [Neurospora cras...
4.0E-34 [23..267] [3..231]
gi|8218220 - gi|8218220|emb|CAB52588.2| PRO1 protein [Sordaria macrospora]
1.0E-29 [1..218] [1..195]
gi|4520324 - gi|4520324|dbj|BAA75888.1| CMR1 [Colletotrichum lagenarium]
2.0E-27 [59..250] [72..295]
gi|7688277 - gi|7688277|emb|CAB89829.1| PRO1 protein [Sordaria brevicollis]
2.0E-27 [1..218] [1..196]

Back

Predicted Domain #1
Region A:
Residues: [1-168]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNTPYNSSV PSIASMTQSS VSRSPNMHTA TTPGANTSSN SPPLHMSSDS SKIKRKRNRI  60
   61 PLSCTICRKR KVKCDKLRPH CQQCTKTGVA HLCHYMEQTW AEEAEKELLK DNELKKLRER 120
  121 VKSLEKTLSK VHSSPSSNSL KSYNTPESSN LFMGSDEHTT LVNANTGS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 463.770868
Match: 1hwtD_
Description: Hap1 (Cyp1); HAP1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.56444258780502 bayes_pls_golite062009
DNA binding 4.26146437716972 bayes_pls_golite062009
nucleic acid binding 4.17369933547911 bayes_pls_golite062009
transcription factor activity 3.049435548132 bayes_pls_golite062009
sequence-specific DNA binding 2.98081393153291 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.93914501897006 bayes_pls_golite062009
binding 2.91929847152301 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 2.44382866473054 bayes_pls_golite062009
transcription activator activity 2.24483536326713 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [169-1502]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASSASHMHQQ QQQQQQQEQQ QDFSRSANAN ANSSSLSISN KYDNDELDLT KDFDLLHIKS  60
   61 NGTIHLGATH WLSIMKGDPY LKLLWGHIFA MREKLNEWYY QKNSYSKLKS SKCPINHAQA 120
  121 PPSAAAAATR KCPVDHSAFS SGMVAPKEET PLPRKCPVDH TMFSSGMIPP REDTSSQKRC 180
  181 PVDHTMYSAG MMPPKDETPS PFSTKAMIDH NKHTMNPPQS KCPVDHRNYM KDYPSDMANS 240
  241 SSNPASRCPI DHSSMKNTAA LPASTHNTIP HHQPQSGSHA RSHPAQSRKH DSYMTESEVL 300
  301 ATLCEMLPPK RVIALFIEKF FKHLYPAIPI LDEQNFKNHV NQMLSLSSMN PTVNNFGMSM 360
  361 PSSSTLENQP ITQINLPKLS DSCNLGILII ILRLTWLSIP SNSCEVDLGE ESGSFLVPNE 420
  421 SSNMSASALT SMAKEESLLL KHETPVEALE LCQKYLIKFD ELSSISNNNV NLTTVQFAIF 480
  481 YNFYMKSASN DLTTLTNTNN TGMANPGHDS ESHQILLSNI TQMAFSCGLH RDPDNFPQLN 540
  541 ATIPATSQDV SNNGSKKANP STNPTLNNNM SAATTNSSSR SGSADSRSGS NPVNKKENQV 600
  601 SIERFKHTWR KIWYYIVSMD VNQSLSLGSP RLLRNLRDFS DTKLPSASRI DYVRDIKELI 660
  661 IVKNFTLFFQ IDLCIIAVLN HILNVSLARS VRKFELDSLI NLLKNLTYGT ENVNDVVSSL 720
  721 INKGLLPTSE GGSVDSNNDE IYGLPKLPDI LNHGQHNQNL YADGRNTSSS DIDKKLDLPH 780
  781 ESTTRALFFS KHMTIRMLLY LLNYILFTHY EPMGSEDPGT NILAKEYAQE ALNFAMDGYR 840
  841 NCMIFFNNIR NTNSLFDYMN VILSYPCLDI GHRSLQFIVC LILRAKCGPL TGMRESSIIT 900
  901 NGTSSGFNSS VEDEDVKVKQ ESSDELKKDD FMKDVNLDSG DSLAEILMSR MLLFQKLTKQ 960
  961 LSKKYNYAIR MNKSTGFFVS LLDTPSKKSD SKSGGSSFML GNWKHPKVSN MSGFLAGDKD1020
 1021 QLQKCPVYQD ALGFVSPTGA NEGSAPMQGM SLQGSTARMG GTQLPPIRSY KPITYTSSNL1080
 1081 RRMNETGEAE AKRRRFNDGY IDNNSNNDIP RGISPKPSNG LSSVQPLLSS FSMNQLNGGT1140
 1141 IPTVPSLTNI TSQMGALPSL DRITTNQINL PDPSRDEAFD NSIKQMTPMT SAFMNANTTI1200
 1201 PSSTLNGNMN MNGAGTANTD TSANGSALST LTSPQGSDLA SNSATQYKPD LEDFLMQNSN1260
 1261 FNGLMINPSS LVEVVGGYND PNNLGRNDAV DFLPVDNVEI DGVGIKINYH LLTSIYVTSI1320
 1321 LSYTVLEDDA NDEK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [202-283]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSLSISNKYD NDELDLTKDF DLLHIKSNGT IHLGATHWLS IMKGDPYLKL LWGHIFAMRE  60
   61 KLNEWYYQKN SYSKLKSSKC PI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [284-462]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NHAQAPPSAA AAATRKCPVD HSAFSSGMVA PKEETPLPRK CPVDHTMFSS GMIPPREDTS  60
   61 SQKRCPVDHT MYSAGMMPPK DETPSPFSTK AMIDHNKHTM NPPQSKCPVD HRNYMKDYPS 120
  121 DMANSSSNPA SRCPIDHSSM KNTAALPAST HNTIPHHQPQ SGSHARSHPA QSRKHDSYM

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [463-710]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TESEVLATLC EMLPPKRVIA LFIEKFFKHL YPAIPILDEQ NFKNHVNQML SLSSMNPTVN  60
   61 NFGMSMPSSS TLENQPITQI NLPKLSDSCN LGILIIILRL TWLSIPSNSC EVDLGEESGS 120
  121 FLVPNESSNM SASALTSMAK EESLLLKHET PVEALELCQK YLIKFDELSS ISNNNVNLTT 180
  181 VQFAIFYNFY MKSASNDLTT LTNTNNTGMA NPGHDSESHQ ILLSNITQMA FSCGLHRDPD 240
  241 NFPQLNAT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [711-756]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IPATSQDVSN NGSKKANPST NPTLNNNMSA ATTNSSSRSG SADSRS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [757-891]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSNPVNKKEN QVSIERFKHT WRKIWYYIVS MDVNQSLSLG SPRLLRNLRD FSDTKLPSAS  60
   61 RIDYVRDIKE LIIVKNFTLF FQIDLCIIAV LNHILNVSLA RSVRKFELDS LINLLKNLTY 120
  121 GTENVNDVVS SLINK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #8
Region A:
Residues: [892-1073]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GLLPTSEGGS VDSNNDEIYG LPKLPDILNH GQHNQNLYAD GRNTSSSDID KKLDLPHEST  60
   61 TRALFFSKHM TIRMLLYLLN YILFTHYEPM GSEDPGTNIL AKEYAQEALN FAMDGYRNCM 120
  121 IFFNNIRNTN SLFDYMNVIL SYPCLDIGHR SLQFIVCLIL RAKCGPLTGM RESSIITNGT 180
  181 SS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #9
Region A:
Residues: [1074-1266]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GFNSSVEDED VKVKQESSDE LKKDDFMKDV NLDSGDSLAE ILMSRMLLFQ KLTKQLSKKY  60
   61 NYAIRMNKST GFFVSLLDTP SKKSDSKSGG SSFMLGNWKH PKVSNMSGFL AGDKDQLQKC 120
  121 PVYQDALGFV SPTGANEGSA PMQGMSLQGS TARMGGTQLP PIRSYKPITY TSSNLRRMNE 180
  181 TGEAEAKRRR FND

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #10
Region A:
Residues: [1267-1387]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GYIDNNSNND IPRGISPKPS NGLSSVQPLL SSFSMNQLNG GTIPTVPSLT NITSQMGALP  60
   61 SLDRITTNQI NLPDPSRDEA FDNSIKQMTP MTSAFMNANT TIPSSTLNGN MNMNGAGTAN 120
  121 T

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #11
Region A:
Residues: [1388-1456]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DTSANGSALS TLTSPQGSDL ASNSATQYKP DLEDFLMQNS NFNGLMINPS SLVEVVGGYN  60
   61 DPNNLGRND

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #12
Region A:
Residues: [1457-1502]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AVDFLPVDNV EIDGVGIKIN YHLLTSIYVT SILSYTVLED DANDEK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle