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View Structure Prediction Details

Protein: ENT2
Organism: Saccharomyces cerevisiae
Length: 613 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ENT2.

Description E-value Query
Range
Subject
Range
gi|119592811, gi... - gi|194248095|ref|NP_001123544.1| epsin 1 isoform b [Homo sapiens], gi|119592814|gb|EAW72408.1| epsin...
6.0E-71 [7..267] [8..269]
EPN1_RAT - Epsin-1 OS=Rattus norvegicus GN=Epn1 PE=1 SV=1
5.0E-70 [7..270] [8..272]
gi|147906994, gi... - gi|2072301|gb|AAC60123.1| mitotic phosphoprotein 90 [Xenopus laevis], gi|147906994|ref|NP_001081892....
4.0E-62 [9..270] [1..268]
lqf-PB, lqf-PD - The gene liquid facets is referred to in FlyBase by the symbol Dmel\lqf (CG8532, FBgn0028582). It is...
9.0E-61 [7..264] [10..259]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
2.0E-60 [7..257] [139..374]
EPN3_MOUSE - Epsin-3 OS=Mus musculus GN=Epn3 PE=1 SV=1
3.0E-56 [7..235] [8..258]

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Predicted Domain #1
Region A:
Residues: [1-159]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKQFVRSAK NMMKGYSSTQ VLVRDATAND SRTPSIDTLD DLAQRSYDSV DFFEIMDMLD  60
   61 KRLNDKGKYW RHVAKSLTVL DYLVRFGSEN CVLWCRENFY VIKTLREFRH ENESGFDEGQ 120
  121 IIRVKAKELV SLLNDEERLR EERSMNTRNR RANRAARPR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 330.54902
Match: 1inzA_
Description: Epsin 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.229007340928547 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [160-521]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PRRQRTRSNP HDSSPSYQDD LEKALEESRI TAQEDEQRRR ELAQYDDEDP DFQAALQLSK  60
   61 EEEELKQLQE LQRLQKQQQS LSQFQAPLQQ QQPQQQPAYY DIFGNPISQD EYLQYQYQQD 120
  121 QEQAMAQQRW LDQQQEQQQL AEQQYFQQQQ QAAAAASALQ QQQTAANMQQ QQQQPADFQQ 180
  181 PLPTGSNNPF SMDNLERQKQ EQQHAQLQRQ QEEARQQQEQ LKLQQLQRQQ QEEAQLHQKR 240
  241 QEEAQLQQQQ AQLLQQQAQF QQQQPLKQTR TGNQSISDKY SDLNTLLATG TGIDTFGNTG 300
  301 EARIPAQHTK TGTFINSQGT GYKQVTNEPK NNPFLSNQYT GLPSTNIVPT QTGYGFGNQP 360
  361 QS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.0
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [522-613]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPTNSPQQNP TGISYSQPQQ QQQPQQQPQY MQNFQQQQPQ YAQNFQQQPQ YTQNYQQQPQ  60
   61 YIQPHQQQQQ QQQQQQQQQG YTPDQGVSLI DL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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