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View Structure Prediction Details

Protein: DIP2
Organism: Saccharomyces cerevisiae
Length: 943 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DIP2.

Description E-value Query
Range
Subject
Range
YY46_NOSS1 - Uncharacterized WD repeat-containing protein alr3466 OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=...
gi|25530855 - pir||AC2239 WD-40 repeat protein [imported] - Nostoc sp. (strain PCC 7120)
0.0 [30..700] [867..1495]
UTP12_YEAST - U3 small nucleolar RNA-associated protein 12 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c...
DIP2 - Nucleolar protein, specifically associated with the U3 snoRNA, part of the large ribonucleoprotein c...
gi|190406158 - gi|190406158|gb|EDV09425.1| DOM34-interacting protein 2 [Saccharomyces cerevisiae RM11-1a]
0.0 [1..943] [1..943]
Y163_SYNY3 - Uncharacterized WD repeat-containing protein sll0163 OS=Synechocystis sp. (strain ATCC 27184 / PCC 6...
Y163_SYNY3 - Uncharacterized WD repeat-containing protein sll0163 OS=Synechocystis sp. (strain PCC 6803 / Kazusa)...
gi|7446132 - pir||S76086 beta transducin-like protein, 190K - Synechocystis sp. (strain PCC 6803)
0.0 [20..729] [1009..1660]

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Predicted Domain #1
Region A:
Residues: [1-66]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVKSYQRFEQ AAAFGVIASN ANCVWIPASS GNSNGSGPGQ LITSALEDVN IWDIKTGDLV  60
   61 SKLSDG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [67-151]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPPGASDARG AKPAECTYLE AHKDTDLLAV GYADGVIKVW DLMSKTVLLN FNGHKAAITL  60
   61 LQFDGTGTRL ISGSKDSNII VWDLV

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 8.065502
Match: PF00400
Description: WD domain, G-beta repeat

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [152-191]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GEVGLYKLRS HKDSITGFWC QGEDWLISTS KDGMIKLWDL 

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 4.0
Match: PF00400
Description: WD domain, G-beta repeat

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [192-242]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KTHQCIETHI AHTGECWGLA VKDDLLITTG TDSQVKIWKL DIENDKMGGK L

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 5.853872
Match: PF00400
Description: WD domain, G-beta repeat

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [243-309]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TEMGIFEKQS KQRGLKIEFI TNSSDKTSFF YIQNADKTIE TFRIRKEEEI ARGLKKREKR  60
   61 LKEKGLT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.867 0.022 small nucleolar ribonucleoprotein complex d.49.1 Signal recognition particle alu RNA binding heterodimer, SRP9/14

Predicted Domain #6
Region A:
Residues: [310-389]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EEEIAKSIKE SYSSFILHPF QTIRSLYKIK SASWTTVSSS KLELVLTTSS NTIEYYSIPY  60
   61 EKRDPTSPAP LKTHTIELQG 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.0
Match: 1c5kA_
Description: TolB, C-terminal domain; TolB, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #7
Region A:
Residues: [390-729]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QRTDVRSIDI SDDNKLLATA SNGSLKIWNI KTHKCIRTFE CGYALTCKFL PGGLLVILGT  60
   61 RNGELQLFDL ASSSLLDTIE DAHDAAIWSL DLTSDGKRLV TGSADKTVKF WDFKVENSLV 120
  121 PGTKNKFLPV LKLHHDTTLE LTDDILCVRV SPDDRYLAIS LLDNTVKVFF LDSMKFYLSL 180
  181 YGHKLPVLSI DISFDSKMII TSSADKNIKI WGLDFGDCHK SLFAHQDSIM NVKFLPQSHN 240
  241 FFSCSKDAVV KYWDGEKFEC IQKLYAHQSE VWALAVATDG GFVVSSSHDH SIRIWEETED 300
  301 QVFLEEEKEK ELEEQYEDTL LTSLEEGNGD DAFKADASGE 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 251.927757
Match: 1erjA_
Description: Tup1, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #8
Region A:
Residues: [730-943]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GVEDEASGVH KQTLESLKAG ERLMEALDLG IAEIEGLEAY NRDMKLWQRK KLGEAPIKPQ  60
   61 GNAVLIAVNK TPEQYIMDTL LRIRMSQLED ALMVMPFSYV LKFLKFIDTV MQNKTLLHSH 120
  121 LPLICKNLFF IIKFNHKELV SQKNEELKLQ INRVKTELRS ALKSTEDDLG FNVQGLKFVK 180
  181 QQWNLRHNYE FVDEYDQQEK ESNSARKRVF GTVI

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle