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View Structure Prediction Details

Protein: DIP2
Organism: Saccharomyces cerevisiae
Length: 943 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DIP2.

Description E-value Query
Range
Subject
Range
YY46_NOSS1 - Uncharacterized WD repeat-containing protein alr3466 OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=...
gi|25530855 - pir||AC2239 WD-40 repeat protein [imported] - Nostoc sp. (strain PCC 7120)
0.0 [30..700] [867..1495]
UTP12_YEAST - U3 small nucleolar RNA-associated protein 12 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c...
DIP2 - Nucleolar protein, specifically associated with the U3 snoRNA, part of the large ribonucleoprotein c...
gi|190406158 - gi|190406158|gb|EDV09425.1| DOM34-interacting protein 2 [Saccharomyces cerevisiae RM11-1a]
0.0 [1..943] [1..943]
Y163_SYNY3 - Uncharacterized WD repeat-containing protein sll0163 OS=Synechocystis sp. (strain ATCC 27184 / PCC 6...
Y163_SYNY3 - Uncharacterized WD repeat-containing protein sll0163 OS=Synechocystis sp. (strain PCC 6803 / Kazusa)...
gi|7446132 - pir||S76086 beta transducin-like protein, 190K - Synechocystis sp. (strain PCC 6803)
0.0 [20..729] [1009..1660]

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Predicted Domain #1
Region A:
Residues: [1-66]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVKSYQRFEQ AAAFGVIASN ANCVWIPASS GNSNGSGPGQ LITSALEDVN IWDIKTGDLV  60
   61 SKLSDG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.442 b.40.4 Nucleic acid-binding proteins
View Download 0.361 d.40.1 CI-2 family of serine protease inhibitors
View Download 0.491 a.60.2 RuvA domain 2-like
View Download 0.361 a.37.1 A DNA-binding domain in eukaryotic transcription factors
View Download 0.364 a.15.1 TAF(II)230 TBP-binding fragment
View Download 0.334 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.331 a.4.1 Homeodomain-like
View Download 0.327 a.64.1 Saposin
View Download 0.317 d.52.5 Probable GTPase Der, C-terminal domain
View Download 0.317 a.16.1 S15/NS1 RNA-binding domain
View Download 0.317 a.64.1 Saposin
View Download 0.308 b.36.1 PDZ domain-like
View Download 0.297 a.39.1 EF-hand
View Download 0.294 d.43.1 Elongation factor Ts (EF-Ts), dimerisation domain
View Download 0.284 a.37.1 A DNA-binding domain in eukaryotic transcription factors
View Download 0.274 a.16.1 S15/NS1 RNA-binding domain
View Download 0.267 a.64.1 Saposin
View Download 0.260 b.36.1 PDZ domain-like
View Download 0.252 b.71.1 Glycosyl hydrolase domain
View Download 0.248 b.36.1 PDZ domain-like
View Download 0.244 d.10.1 DNA-binding domain
View Download 0.238 a.64.1 Saposin
View Download 0.236 a.46.1 Methionine synthase domain
View Download 0.234 d.120.1 Cytochrome b5
View Download 0.234 a.4.5 "Winged helix" DNA-binding domain
View Download 0.234 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.231 a.112.1 Description not found.
View Download 0.224 d.120.1 Cytochrome b5
View Download 0.223 a.39.1 EF-hand
View Download 0.213 b.36.1 PDZ domain-like
View Download 0.213 a.64.1 Saposin
View Download 0.213 a.12.1 Kix domain of CBP (creb binding protein)
View Download 0.208 b.71.1 Glycosyl hydrolase domain
View Download 0.201 d.43.1 Elongation factor Ts (EF-Ts), dimerisation domain
View Download 0.200 a.39.1 EF-hand

Predicted Domain #2
Region A:
Residues: [67-151]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPPGASDARG AKPAECTYLE AHKDTDLLAV GYADGVIKVW DLMSKTVLLN FNGHKAAITL  60
   61 LQFDGTGTRL ISGSKDSNII VWDLV

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 8.065502
Match: PF00400
Description: WD domain, G-beta repeat

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [152-191]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GEVGLYKLRS HKDSITGFWC QGEDWLISTS KDGMIKLWDL 

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 4.0
Match: PF00400
Description: WD domain, G-beta repeat

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [192-242]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KTHQCIETHI AHTGECWGLA VKDDLLITTG TDSQVKIWKL DIENDKMGGK L

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 5.853872
Match: PF00400
Description: WD domain, G-beta repeat

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.798 N/A N/A a.47.2 t-snare proteins
View Download 0.602 N/A N/A a.7.4 Smac/diablo
View Download 0.567 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.566 N/A N/A a.39.1 EF-hand
View Download 0.550 N/A N/A a.7.1 Spectrin repeat

Predicted Domain #5
Region A:
Residues: [243-309]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TEMGIFEKQS KQRGLKIEFI TNSSDKTSFF YIQNADKTIE TFRIRKEEEI ARGLKKREKR  60
   61 LKEKGLT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.768 0.022 small nucleolar ribonucleoprotein complex d.50.1 dsRNA-binding domain-like
View Download 0.867 0.022 small nucleolar ribonucleoprotein complex d.49.1 Signal recognition particle alu RNA binding heterodimer, SRP9/14
View Download 0.815 0.022 small nucleolar ribonucleoprotein complex d.50.2 Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain
View Download 0.610 0.022 small nucleolar ribonucleoprotein complex d.50.1 dsRNA-binding domain-like
View Download 0.601 0.022 small nucleolar ribonucleoprotein complex d.50.1 dsRNA-binding domain-like
View Download 0.567 0.022 small nucleolar ribonucleoprotein complex d.93.1 SH2 domain
View Download 0.539 0.022 small nucleolar ribonucleoprotein complex d.129.1 TATA-box binding protein-like
View Download 0.536 0.022 small nucleolar ribonucleoprotein complex d.10.1 DNA-binding domain
View Download 0.518 0.022 small nucleolar ribonucleoprotein complex d.105.1 Clathrin adaptor appendage, alpha and beta chain-specific domain
View Download 0.478 0.022 small nucleolar ribonucleoprotein complex d.58.8 Viral DNA-binding domain
View Download 0.465 0.022 small nucleolar ribonucleoprotein complex c.47.2 RNA 3'-terminal phosphate cyclase, RPTC, insert domain
View Download 0.450 0.022 small nucleolar ribonucleoprotein complex d.51.1 Eukaryotic type KH-domain (KH-domain type I)
View Download 0.440 0.022 small nucleolar ribonucleoprotein complex d.141.1 Ribosomal protein L6
View Download 0.433 0.022 small nucleolar ribonucleoprotein complex d.51.1 Eukaryotic type KH-domain (KH-domain type I)
View Download 0.430 0.022 small nucleolar ribonucleoprotein complex b.84.2 Rudiment single hybrid motif
View Download 0.423 0.022 small nucleolar ribonucleoprotein complex d.204.1 Ribosome binding protein Y (YfiA homologue)
View Download 0.423 0.022 small nucleolar ribonucleoprotein complex b.24.1 Hyaluronate lyase-like, C-terminal domain
View Download 0.408 0.022 small nucleolar ribonucleoprotein complex d.58.17 Metal-binding domain
View Download 0.407 0.022 small nucleolar ribonucleoprotein complex d.129.2 Phosphoglucomutase, C-terminal domain
View Download 0.397 0.022 small nucleolar ribonucleoprotein complex b.71.1 Glycosyl hydrolase domain
View Download 0.395 0.022 small nucleolar ribonucleoprotein complex d.9.1 Interleukin 8-like chemokines
View Download 0.387 0.022 small nucleolar ribonucleoprotein complex d.50.1 dsRNA-binding domain-like
View Download 0.383 0.022 small nucleolar ribonucleoprotein complex d.58.7 RNA-binding domain, RBD
View Download 0.371 0.022 small nucleolar ribonucleoprotein complex d.58.7 RNA-binding domain, RBD
View Download 0.370 0.022 small nucleolar ribonucleoprotein complex d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.369 0.022 small nucleolar ribonucleoprotein complex d.58.7 RNA-binding domain, RBD
View Download 0.366 0.022 small nucleolar ribonucleoprotein complex c.58.1 Aminoacid dehydrogenase-like, N-terminal domain
View Download 0.364 0.022 small nucleolar ribonucleoprotein complex b.71.1 Glycosyl hydrolase domain
View Download 0.353 0.022 small nucleolar ribonucleoprotein complex d.9.2 Description not found.
View Download 0.351 0.022 small nucleolar ribonucleoprotein complex d.58.17 Metal-binding domain
View Download 0.335 0.022 small nucleolar ribonucleoprotein complex d.10.1 DNA-binding domain
View Download 0.330 0.022 small nucleolar ribonucleoprotein complex d.129.1 TATA-box binding protein-like
View Download 0.328 0.022 small nucleolar ribonucleoprotein complex b.71.1 Glycosyl hydrolase domain
View Download 0.317 0.022 small nucleolar ribonucleoprotein complex b.40.6 MOP-like
View Download 0.313 0.022 small nucleolar ribonucleoprotein complex b.71.1 Glycosyl hydrolase domain
View Download 0.305 0.022 small nucleolar ribonucleoprotein complex b.40.4 Nucleic acid-binding proteins
View Download 0.299 0.022 small nucleolar ribonucleoprotein complex d.58.3 Protease propeptides/inhibitors
View Download 0.297 0.022 small nucleolar ribonucleoprotein complex c.51.1 Anticodon-binding domain of Class II aaRS
View Download 0.296 0.022 small nucleolar ribonucleoprotein complex d.16.1 FAD-linked reductases, C-terminal domain
View Download 0.296 0.022 small nucleolar ribonucleoprotein complex d.129.1 TATA-box binding protein-like
View Download 0.279 0.022 small nucleolar ribonucleoprotein complex b.71.1 Glycosyl hydrolase domain
View Download 0.278 0.022 small nucleolar ribonucleoprotein complex d.57.1 DNA damage-inducible protein DinI
View Download 0.275 0.022 small nucleolar ribonucleoprotein complex d.51.1 Eukaryotic type KH-domain (KH-domain type I)
View Download 0.269 0.022 small nucleolar ribonucleoprotein complex b.84.2 Rudiment single hybrid motif
View Download 0.268 0.022 small nucleolar ribonucleoprotein complex c.52.2 tRNA splicing endonuclease, C-terminal domain
View Download 0.267 0.022 small nucleolar ribonucleoprotein complex d.58.23 Probable ACP-binding domain of malonyl-CoA ACP transacylase
View Download 0.266 0.022 small nucleolar ribonucleoprotein complex c.47.1 Thioredoxin-like
View Download 0.264 0.022 small nucleolar ribonucleoprotein complex d.58.49 YajQ-like
View Download 0.262 0.022 small nucleolar ribonucleoprotein complex c.102.1 Cell-division inhibitor MinC, N-terminal domain
View Download 0.261 0.022 small nucleolar ribonucleoprotein complex b.60.1 Lipocalins
View Download 0.255 0.022 small nucleolar ribonucleoprotein complex b.71.1 Glycosyl hydrolase domain
View Download 0.251 0.022 small nucleolar ribonucleoprotein complex b.1.2 Fibronectin type III
View Download 0.246 0.022 small nucleolar ribonucleoprotein complex d.58.17 Metal-binding domain
View Download 0.246 0.022 small nucleolar ribonucleoprotein complex d.233.1 Inhibitor of vertebrate lysozyme, Ivy
View Download 0.245 0.022 small nucleolar ribonucleoprotein complex d.58.17 Metal-binding domain
View Download 0.238 0.022 small nucleolar ribonucleoprotein complex d.58.3 Protease propeptides/inhibitors
View Download 0.230 0.022 small nucleolar ribonucleoprotein complex d.58.7 RNA-binding domain, RBD
View Download 0.225 0.022 small nucleolar ribonucleoprotein complex d.52.5 Probable GTPase Der, C-terminal domain
View Download 0.223 0.022 small nucleolar ribonucleoprotein complex d.58.10 Acylphosphatase-like
View Download 0.219 0.022 small nucleolar ribonucleoprotein complex d.52.3 Prokaryotic type KH domain (KH-domain type II)
View Download 0.216 0.022 small nucleolar ribonucleoprotein complex c.55.7 Methylated DNA-protein cysteine methyltransferase domain
View Download 0.216 0.022 small nucleolar ribonucleoprotein complex d.54.1 Enolase N-terminal domain-like
View Download 0.214 0.022 small nucleolar ribonucleoprotein complex d.16.1 FAD-linked reductases, C-terminal domain
View Download 0.214 0.022 small nucleolar ribonucleoprotein complex b.1.2 Fibronectin type III
View Download 0.212 0.022 small nucleolar ribonucleoprotein complex b.1.2 Fibronectin type III
View Download 0.211 0.022 small nucleolar ribonucleoprotein complex b.55.1 PH domain-like
View Download 0.206 0.022 small nucleolar ribonucleoprotein complex c.47.1 Thioredoxin-like
View Download 0.204 0.022 small nucleolar ribonucleoprotein complex d.58.1 4Fe-4S ferredoxins

Predicted Domain #6
Region A:
Residues: [310-389]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EEEIAKSIKE SYSSFILHPF QTIRSLYKIK SASWTTVSSS KLELVLTTSS NTIEYYSIPY  60
   61 EKRDPTSPAP LKTHTIELQG 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.0
Match: 1c5kA_
Description: TolB, C-terminal domain; TolB, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #7
Region A:
Residues: [390-729]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QRTDVRSIDI SDDNKLLATA SNGSLKIWNI KTHKCIRTFE CGYALTCKFL PGGLLVILGT  60
   61 RNGELQLFDL ASSSLLDTIE DAHDAAIWSL DLTSDGKRLV TGSADKTVKF WDFKVENSLV 120
  121 PGTKNKFLPV LKLHHDTTLE LTDDILCVRV SPDDRYLAIS LLDNTVKVFF LDSMKFYLSL 180
  181 YGHKLPVLSI DISFDSKMII TSSADKNIKI WGLDFGDCHK SLFAHQDSIM NVKFLPQSHN 240
  241 FFSCSKDAVV KYWDGEKFEC IQKLYAHQSE VWALAVATDG GFVVSSSHDH SIRIWEETED 300
  301 QVFLEEEKEK ELEEQYEDTL LTSLEEGNGD DAFKADASGE 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 251.927757
Match: 1erjA_
Description: Tup1, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #8
Region A:
Residues: [730-943]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GVEDEASGVH KQTLESLKAG ERLMEALDLG IAEIEGLEAY NRDMKLWQRK KLGEAPIKPQ  60
   61 GNAVLIAVNK TPEQYIMDTL LRIRMSQLED ALMVMPFSYV LKFLKFIDTV MQNKTLLHSH 120
  121 LPLICKNLFF IIKFNHKELV SQKNEELKLQ INRVKTELRS ALKSTEDDLG FNVQGLKFVK 180
  181 QQWNLRHNYE FVDEYDQQEK ESNSARKRVF GTVI

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle