YRC Public Data Repository - Protein Structure Prediction

Protein:	YLR126C
Organism:	Saccharomyces cerevisiae
Length:	251 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YLR126C.

Description	E-value	Query Range	Subject Range
gi\|2983181, gi\|1... - gi\|2983181\|gb\|AAC06781.1\| anthranilate synthase component II [Aquifex aeolicus VF5], gi\|15606008\|ref... gi\|7436747 - pir\|\|E70349 anthranilate synthase component II - Aquifex aeolicus	1.0E-56	[14..220]	[2..191]
gi\|197938528, gi... - gi\|198244012\|ref\|YP_002217430.1\| aminodeoxychorismate synthase, component II [Salmonella enterica su... gi\|197265499, gi... - gi\|197265499\|ref\|ZP_03165573.1\| aminodeoxychorismate synthase, component II [Salmonella enterica sub... gi\|197247694, gi... - gi\|197247694\|ref\|YP_002148388.1\| aminodeoxychorismate synthase, component II [Salmonella enterica su... PABA_SALTY - Aminodeoxychorismate synthase component 2 OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 70... gi\|167994569, gi... - gi\|205327603\|gb\|EDZ14367.1\| aminodeoxychorismate synthase, component II [Salmonella enterica subsp. ... PABA_SALTY - Para-aminobenzoate synthase glutamine amidotransferase component II OS=Salmonella typhimurium GN=pab... gi\|207858710, gi... - gi\|207858710\|ref\|YP_002245361.1\| para-aminobenzoate synthase component II [Salmonella enterica subsp... lcl\|NC_016856.1_... - [gene=pabA] [protein=para-aminobenzoate synthase component II] [protein_id=YP_005239662.1] [location... PABA_SALTY - Para-aminobenzoate synthase glutamine amidotransferase component II OS=Salmonella typhimurium GN=pab...	2.0E-56	[15..216]	[2..186]
gi\|217324460, gi... - gi\|217324460\|ref\|ZP_03440544.1\| aminodeoxychorismate synthase, component II [Escherichia coli O157:H... gi\|208812957, gi... - gi\|208812957\|ref\|ZP_03254286.1\| aminodeoxychorismate synthase, component II [Escherichia coli O157:H... gi\|208729357, gi... - gi\|208809556\|ref\|ZP_03251893.1\| aminodeoxychorismate synthase, component II [Escherichia coli O157:H... gi\|209157464, gi... - gi\|209396064\|ref\|YP_002272802.1\| aminodeoxychorismate synthase, component II [Escherichia coli O157:... gi\|208821415, gi... - gi\|208821415\|ref\|ZP_03261735.1\| aminodeoxychorismate synthase, component II [Escherichia coli O157:H... gi\|13363684, gi\|... - gi\|15833465\|ref\|NP_312238.1\| para-aminobenzoate synthase component II [Escherichia coli O157:H7], gi... gi\|168785170, gi... - gi\|189374309\|gb\|EDU92725.1\| aminodeoxychorismate synthase, component II [Escherichia coli O157:H7 st... gi\|209756822, gi... - pir\|\|H86000 p-aminobenzoate synthetase, component II [imported] - Escherichia coli (strain O157:H7, ... gi\|189002404, gi... - gi\|189002404\|gb\|EDU71390.1\| aminodeoxychorismate synthase, component II [Escherichia coli O157:H7 st... gi\|195934858 - gi\|195934858\|ref\|ZP_03080240.1\| para-aminobenzoate synthase component II [Escherichia coli O157:H7 s... gi\|15803874, gi\|... - gi\|15803874\|ref\|NP_289908.1\| para-aminobenzoate synthase component II [Escherichia coli O157:H7 EDL9... gi\|189380149, gi... - gi\|189380149\|gb\|EDU98565.1\| aminodeoxychorismate synthase, component II [Escherichia coli O157:H7 st... gi\|189369905, gi... - gi\|189369905\|gb\|EDU88321.1\| aminodeoxychorismate synthase, component II [Escherichia coli O157:H7 st... gi\|189359113, gi... - gi\|189359113\|gb\|EDU77532.1\| aminodeoxychorismate synthase, component II [Escherichia coli O157:H7 st... gi\|168772742, gi... - gi\|187771712\|gb\|EDU35556.1\| aminodeoxychorismate synthase, component II [Escherichia coli O157:H7 st... gi\|168765713, gi... - gi\|189364793\|gb\|EDU83212.1\| aminodeoxychorismate synthase, component II [Escherichia coli O157:H7 st... gi\|188014202, gi... - gi\|188014202\|gb\|EDU52324.1\| aminodeoxychorismate synthase, component II [Escherichia coli O157:H7 st... gi\|254795284, gi... - gi\|254795284\|ref\|YP_003080121.1\| aminodeoxychorismate synthase, subunit II [Escherichia coli O157:H7... gi\|13363684, gi\|... - gi\|15833465\|ref\|NP_312238.1\| para-aminobenzoate synthase component II [Escherichia coli O157:H7 str....	2.0E-56	[15..216]	[2..186]
gi\|204322280, gi... - gi\|204928847\|ref\|ZP_03220046.1\| aminodeoxychorismate synthase, component II [Salmonella enterica sub... gi\|213053379 - gi\|213053379\|ref\|ZP_03346257.1\| para-aminobenzoate synthase component II [Salmonella enterica subsp.... gi\|238913593 - gi\|238913593\|ref\|ZP_04657430.1\| para-aminobenzoate synthase component II [Salmonella enterica subsp.... gi\|213426760 - gi\|213426760\|ref\|ZP_03359510.1\| para-aminobenzoate synthase component II [Salmonella enterica subsp.... gi\|213581580 - gi\|213581580\|ref\|ZP_03363406.1\| para-aminobenzoate synthase component II [Salmonella enterica subsp.... gi\|205333159, gi... - gi\|205333159\|gb\|EDZ19923.1\| aminodeoxychorismate synthase, component II [Salmonella enterica subsp. ... gi\|197291379, gi... - gi\|197291379\|gb\|EDY30731.1\| aminodeoxychorismate synthase, component II [Salmonella enterica subsp. ... gi\|194455231, gi... - gi\|194468867\|ref\|ZP_03074851.1\| aminodeoxychorismate synthase, component II [Salmonella enterica sub... gi\|194737562, gi... - gi\|194737562\|ref\|YP_002116412.1\| aminodeoxychorismate synthase, component II [Salmonella enterica su... gi\|16505122, gi\|... - gi\|25291375\|pir\|\|AD1002 para-aminobenzoate synthase, glutamine amidotransferase component II (EC 4.1... gi\|29139940, gi\|... - gi\|29144303\|ref\|NP_807645.1\| para-aminobenzoate synthase component II [Salmonella enterica subsp. en... gi\|16762816 - gi\|16762816\|ref\|NP_458433.1\| para-aminobenzoate synthase component II [Salmonella enterica subsp. en... gi\|213864793 - gi\|213864793\|ref\|ZP_03386912.1\| para-aminobenzoate synthase component II [Salmonella enterica subsp.... gi\|213976486 - gi\|213976486\|ref\|ZP_03403745.1\| para-aminobenzoate synthase component II [Salmonella enterica subsp.... gi\|214000206 - gi\|214000206\|ref\|ZP_03410941.1\| para-aminobenzoate synthase component II [Salmonella enterica subsp....	3.0E-56	[15..216]	[2..186]
gi\|254163288, gi... - gi\|254163288\|ref\|YP_003046396.1\| para-aminobenzoate synthase component II [Escherichia coli B str. R... PABA_ECOLI - Para-aminobenzoate synthase glutamine amidotransferase component II (EC 6.3.5.8) (ADC synthase) - Es... gi\|157078316, gi... - gi\|75188136\|ref\|ZP_00701403.1\| COG0512: Anthranilate/para-aminobenzoate synthases component II [Esch... gi\|157068517, gi... - gi\|75197293\|ref\|ZP_00707363.1\| COG0512: Anthranilate/para-aminobenzoate synthases component II [Esch... gi\|194421560, gi... - gi\|83585128\|ref\|ZP_00923780.1\| COG0512: Anthranilate/para-aminobenzoate synthases component II [Esch... EG10682 - aminodeoxychorismate synthase, subunit II / Sulfonamide resistance; p-aminobenzoate biosynthesis EG10682 - aminodeoxychorismate synthase, subunit II / Sulfonamide resistance; p-aminobenzoate biosynthesis gi\|193061732, gi... - gi\|75260349\|ref\|ZP_00731617.1\| COG0512: Anthranilate/para-aminobenzoate synthases component II [Esch... gi\|188488439, gi... - gi\|75516170\|ref\|ZP_00738288.1\| COG0512: Anthranilate/para-aminobenzoate synthases component II [Esch... gi\|194414984, gi... - gi\|75211728\|ref\|ZP_00711792.1\| COG0512: Anthranilate/para-aminobenzoate synthases component II [Esch... gi\|169890713, gi... - gi\|170082878\|ref\|YP_001732198.1\| aminodeoxychorismate synthase, subunit II [Escherichia coli str. K-... gi\|75228402, gi\|... - gi\|75228402\|ref\|ZP_00715048.1\| COG0512: Anthranilate/para-aminobenzoate synthases component II [Esch... gi\|218362674, gi... - gi\|218555906\|ref\|YP_002388819.1\| para-aminobenzoate synthase component II [Escherichia coli IAI1], g... gi\|238902452, gi... - gi\|238902452\|ref\|YP_002928248.1\| aminodeoxychorismate synthase, subunit II [Escherichia coli BW2952]... gi\|209914072, gi... - gi\|209920813\|ref\|YP_002294897.1\| para-aminobenzoate synthase component II [Escherichia coli SE11], g... gi\|251786614, gi... - gi\|251786614\|ref\|YP_003000918.1\| hypothetical protein B21_03163 [Escherichia coli BL21], gi\|24237888... gi\|89110649, gi\|... - gi\|89110649\|ref\|AP_004429.1\| aminodeoxychorismate synthase, subunit II [Escherichia coli str. K-12 s... gi\|253771813, gi... - gi\|254290038\|ref\|YP_003055786.1\| para-aminobenzoate synthase component II [Escherichia coli BL21(DE3... gi\|218353773, gi... - gi\|218697041\|ref\|YP_002404708.1\| para-aminobenzoate synthase component II [Escherichia coli 55989], ... gi\|254038523, gi... - gi\|254038523\|ref\|ZP_04872579.1\| para-aminobenzoate synthase component II [Escherichia sp. 1_1_43], g...	5.0E-56	[15..216]	[2..186]
TRPG_PICAN - Anthranilate synthase component 2 (Fragment) OS=Pichia angusta PE=4 SV=1 TRPG_PICAN - Multifunctional tryptophan biosynthesis protein (Fragment) OS=Pichia angusta PE=3 SV=1	7.0E-56	[11..236]	[4..213]
gi\|169014 - gi\|169014\|gb\|AAA33633.1\| trifunctional protein with glutamine amidotransferase (TrpG), phosphoribosy...	1.0E-55	[15..225]	[3..197]
gi\|15642614, gi\|... - gi\|9657208\|gb\|AAF95760.1\| para-aminobenzoate synthase glutamine amidotransferase, component II [Vibr... gi\|229507329, gi... - gi\|229507329\|ref\|ZP_04396834.1\| para-aminobenzoate synthase amidotransferase component [Vibrio chole... gi\|229345935, gi... - gi\|229516872\|ref\|ZP_04406318.1\| para-aminobenzoate synthase amidotransferase component [Vibrio chole... gi\|229338176, gi... - gi\|229524595\|ref\|ZP_04414000.1\| para-aminobenzoate synthase amidotransferase component [Vibrio chole... gi\|229369490, gi... - gi\|229606835\|ref\|YP_002877483.1\| para-aminobenzoate synthase amidotransferase component [Vibrio chol... gi\|116190614, gi... - gi\|75829428\|ref\|ZP_00758731.1\| COG0512: Anthranilate/para-aminobenzoate synthases component II [Vibr... gi\|11268518 - pir\|\|G82054 para-aminobenzoate synthase glutamine amidotransferase, component II VC2619 [imported] -... gi\|121547643, gi... - gi\|121588100\|ref\|ZP_01677848.1\| para-aminobenzoate synthase glutamine amidotransferase, component II... gi\|126510423, gi... - gi\|153819042\|ref\|ZP_01971709.1\| para-aminobenzoate synthase glutamine amidotransferase, component II... gi\|229353221, gi... - gi\|229509747\|ref\|ZP_04399228.1\| para-aminobenzoate synthase amidotransferase component [Vibrio chole...	1.0E-55	[16..216]	[3..191]
TRPG_PSEAE - Anthranilate synthase component 2 OS=Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101... TRPG_PSEAE - Anthranilate synthase component II OS=Pseudomonas aeruginosa GN=trpG PE=4 SV=2	4.0E-55	[16..224]	[3..199]

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Predicted Domain #1

Region A:
Residues: [1-251]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTVKKIAILY TDEDNEWSKP WGNFVDMAIK LLEQTRKLEC IAEDVEYEVF HVQKNVFPQL  60
   61 SDLQKDEYLG IYITGSKYDS FDNEIEWIMK LRSFLNEMLT SKTEYPPVAG ICFGHQVIAA 120
  121 ALGSSVGRNP KGFEGGVVSL KLNSVGQKLF GAQELNLSEV HSDCVFDVPE GYQNWASSEK 180
  181 CQNQGFYRQN RVLTFQGHPE FNSDVAQKGL LKSQDKLTLE EFNRYERQCQ ELDNNGIQAA 240
  241 RNIWRLFLQK I

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term	Confidence	Notes
ligase activity	3.61930974415557	bayes_pls_golite062009
catalytic activity	1.30391542469987	bayes_pls_golite062009
binding	0.390233002411274	bayes_pls_golite062009
nucleic acid binding	0.35869985654229	bayes_pls_golite062009
carbon-nitrogen ligase activity, with glutamine as amido-N-donor	0.253024564578883	bayes_pls_golite062009
anthranilate synthase activity	0.198608229600186	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: