YRC Public Data Repository - Protein Structure Prediction

Protein:	AVL9
Organism:	Saccharomyces cerevisiae
Length:	764 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AVL9.

Description	E-value	Query Range	Subject Range
gi\|190406147 - gi\|190406147\|gb\|EDV09414.1\| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a] AVL9_YEAST - Late secretory pathway protein AVL9 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=AVL9... AVL9 - Conserved protein involved in exocytic transport from the Golgi; mutation is synthetically lethal wi... gi\|151941279 - gi\|151941279\|gb\|EDN59657.1\| conserved protein [Saccharomyces cerevisiae YJM789]	0.0	[1..764]	[1..764]
AVL9_SCHPO - Late secretory pathway protein avl9 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=avl9 P... SPAC23H3.14 - LAlv9 family protein	0.0	[1..474]	[1..437]
CE29822 - status:Partially_confirmed UniProt:Q22794 protein_id:AAC77509.3	0.0	[9..493]	[4..466]
gi\|70995820, gi\|... - gi\|70995820\|ref\|XP_752665.1\| Avl9 protein [Aspergillus fumigatus Af293], gi\|66850300\|gb\|EAL90627.1\| ... gi\|42820697, gi\|... - gi\|42820697\|emb\|CAF32010.1\| hypothetical protein, conserved [Aspergillus fumigatus], gi\|19577356\|emb... gi\|159131419 - gi\|159131419\|gb\|EDP56532.1\| Avl9 protein, putative [Aspergillus fumigatus A1163]	0.0	[58..499]	[45..454]
gi\|1663700 - gi\|1663700\|dbj\|BAA13435.1\| KIAA0241 [Homo sapiens]	5.0E-66	[57..244]	[1..168]
CG3309-PA - This gene is referred to in FlyBase by the symbol Dmel\CG3309 (CG3309, FBgn0029756). It is a protein...	1.0E-57	[10..167]	[48..193]
gi\|22122407, gi\|... - gi\|22122407\|ref\|NP_666081.1\| hypothetical protein LOC211922 isoform b [Mus musculus], gi\|19343701\|gb...	3.0E-52	[7..151]	[57..198]

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Predicted Domain #1

Region A:
Residues: [1-169]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDEHEEAVIF GICLVDFHHK RGPEIEYWYG LPEGTQSAEL WPNLPFQALP DGSHSFEETF  60
   61 TYFTLLYDER RQRSPPNGAT DLSDDSINDN TTLFAISCSR QIKSDELVTK DKDVTRSTVQ 120
  121 KAIVVISRQP IFGQIKDKLS IVTNAFFLQH DFGDRKIIQS LYENLKSIY

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [170-287]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPASLVRNAE NRLYIGLCLR KILHDFKRNA LVLLKAIMLE KKIIVYGNDV EALCNLQFGL  60
   61 ISLIPDLMSN LQDSGSPQLF QDISKLNVVD SFKSSNRESV LRFLGFPLPI FEKGGLFS

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [288-764]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PYTPLQQMND IRSERTLFFM IGSSNTLLAE QKEELCHIFV NTDNSTVDIL DKTLNPVLQL  60
   61 SSHDKKWIES ISGIVSDTWN ENDDETPKNS QFEGSEDFIR WQFEDYLTGL LSSVKLSDYL 120
  121 DLHKENDQAL KTIPEDMLNS NPVHLFNLNW VQSWKETQNF LIFNSRTDDR LFDLFPPKHI 180
  181 YNGADTLSLL QQRFLATFHN LKRSSSNSSS NKNGHQSEED IKDQESIESK KSVSQISVNP 240
  241 GKNTDKPAAN LWNSWKEYFN KPKNTANEDV TESTEDLKNR SKTSNAIQKA MMGLGLHYKP 300
  301 DAETDQQSEE VGNSEDNEDD DTDEDSEDDD DDGGDDDDSE DDDDDDDGEG DENGDDGEGD 360
  361 ENGDDGEGDE NGDKEDSQDF SNGFTDVTNI NTDHDKENEQ NFEGNAENFN EDETVADKDI 420
  421 EGGPESNKNS DSKTDIYEND RNVEDSSKTR NTVKKSNEEG GANDAAIGNC VQDEEKL

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [429-597]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PVHLFNLNWV QSWKETQNFL IFNSRTDDRL FDLFPPKHIY NGADTLSLLQ QRFLATFHNL  60
   61 KRSSSNSSSN KNGHQSEEDI KDQESIESKK SVSQISVNPG KNTDKPAANL WNSWKEYFNK 120
  121 PKNTANEDVT ESTEDLKNRS KTSNAIQKAM MGLGLHYKPD AETDQQSEE

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5

Region A:
Residues: [598-764]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VGNSEDNEDD DTDEDSEDDD DDGGDDDDSE DDDDDDDGEG DENGDDGEGD ENGDDGEGDE  60
   61 NGDKEDSQDF SNGFTDVTNI NTDHDKENEQ NFEGNAENFN EDETVADKDI EGGPESNKNS 120
  121 DSKTDIYEND RNVEDSSKTR NTVKKSNEEG GANDAAIGNC VQDEEKL

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits