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View Structure Prediction Details

Protein: AVL9
Organism: Saccharomyces cerevisiae
Length: 764 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AVL9.

Description E-value Query
Range
Subject
Range
gi|190406147 - gi|190406147|gb|EDV09414.1| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a]
AVL9_YEAST - Late secretory pathway protein AVL9 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=AVL9...
AVL9 - Conserved protein involved in exocytic transport from the Golgi; mutation is synthetically lethal wi...
gi|151941279 - gi|151941279|gb|EDN59657.1| conserved protein [Saccharomyces cerevisiae YJM789]
0.0 [1..764] [1..764]
AVL9_SCHPO - Late secretory pathway protein avl9 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=avl9 P...
SPAC23H3.14 - LAlv9 family protein
0.0 [1..474] [1..437]
CE29822 - status:Partially_confirmed UniProt:Q22794 protein_id:AAC77509.3
0.0 [9..493] [4..466]
gi|70995820, gi|... - gi|70995820|ref|XP_752665.1| Avl9 protein [Aspergillus fumigatus Af293], gi|66850300|gb|EAL90627.1| ...
gi|42820697, gi|... - gi|42820697|emb|CAF32010.1| hypothetical protein, conserved [Aspergillus fumigatus], gi|19577356|emb...
gi|159131419 - gi|159131419|gb|EDP56532.1| Avl9 protein, putative [Aspergillus fumigatus A1163]
0.0 [58..499] [45..454]
gi|1663700 - gi|1663700|dbj|BAA13435.1| KIAA0241 [Homo sapiens]
5.0E-66 [57..244] [1..168]
CG3309-PA - This gene is referred to in FlyBase by the symbol Dmel\CG3309 (CG3309, FBgn0029756). It is a protein...
1.0E-57 [10..167] [48..193]
gi|22122407, gi|... - gi|22122407|ref|NP_666081.1| hypothetical protein LOC211922 isoform b [Mus musculus], gi|19343701|gb...
3.0E-52 [7..151] [57..198]

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Predicted Domain #1
Region A:
Residues: [1-169]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDEHEEAVIF GICLVDFHHK RGPEIEYWYG LPEGTQSAEL WPNLPFQALP DGSHSFEETF  60
   61 TYFTLLYDER RQRSPPNGAT DLSDDSINDN TTLFAISCSR QIKSDELVTK DKDVTRSTVQ 120
  121 KAIVVISRQP IFGQIKDKLS IVTNAFFLQH DFGDRKIIQS LYENLKSIY

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [170-287]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPASLVRNAE NRLYIGLCLR KILHDFKRNA LVLLKAIMLE KKIIVYGNDV EALCNLQFGL  60
   61 ISLIPDLMSN LQDSGSPQLF QDISKLNVVD SFKSSNRESV LRFLGFPLPI FEKGGLFS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.642 a.7.1 Spectrin repeat
View Download 0.618 a.74.1 Cyclin-like
View Download 0.618 a.74.1 Cyclin-like
View Download 0.642 a.7.1 Spectrin repeat
View Download 0.797 a.24.4 Hemerythrin
View Download 0.689 a.90.1 Transcription factor STAT-4 N-domain
View Download 0.797 a.24.4 Hemerythrin
View Download 0.689 a.90.1 Transcription factor STAT-4 N-domain
View Download 0.627 a.7.1 Spectrin repeat
View Download 0.546 d.68.6 DNA-binding protein Sso10b (AlbA)
View Download 0.538 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.530 d.110.4 SNARE-like
View Download 0.511 a.24.3 Cytochromes
View Download 0.490 d.56.1 GroEL-intermediate domain like
View Download 0.481 c.23.1 CheY-like
View Download 0.477 a.18.1 T4 endonuclease V
View Download 0.466 c.2.1 NAD(P)-binding Rossmann-fold domains
View Download 0.464 a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.430 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.420 a.47.2 t-snare proteins
View Download 0.413 a.24.9 alpha-catenin/vinculin
View Download 0.394 f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.388 c.25.1 Ferredoxin reductase-like, C-terminal NADP-linked domain
View Download 0.379 a.2.3 Chaperone J-domain
View Download 0.367 c.23.1 CheY-like
View Download 0.366 a.24.17 Group V grass pollen allergen
View Download 0.355 d.65.1 Hedgehog/DD-pepidase
View Download 0.355 c.13.2 Anti-sigma factor antagonist SpoIIaa
View Download 0.344 a.7.3 Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain
View Download 0.326 a.40.1 Calponin-homology domain, CH-domain
View Download 0.321 a.60.9 lambda integrase-like, N-terminal domain
View Download 0.312 d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.308 d.54.1 Enolase N-terminal domain-like
View Download 0.304 a.47.2 t-snare proteins
View Download 0.300 a.48.1 N-terminal domain of cbl (N-cbl)
View Download 0.298 d.38.1 Thioesterase/thiol ester dehydrase-isomerase
View Download 0.295 a.26.1 4-helical cytokines
View Download 0.290 a.60.9 lambda integrase-like, N-terminal domain
View Download 0.290 a.8.3 Families 57/38 glycoside transferase middle domain
View Download 0.289 d.208.1 MTH1598-like
View Download 0.288 a.1.1 Globin-like
View Download 0.275 d.81.1 Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
View Download 0.270 a.74.1 Cyclin-like
View Download 0.269 a.69.3 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain
View Download 0.258 a.60.7 5' to 3' exonuclease, C-terminal subdomain
View Download 0.258 a.1.1 Globin-like
View Download 0.257 d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.257 d.109.1 Actin depolymerizing proteins
View Download 0.254 d.65.1 Hedgehog/DD-pepidase
View Download 0.247 d.58.33 Formylmethanofuran:tetrahydromethanopterin formyltransferase
View Download 0.247 a.71.2 Helical domain of Sec23/24
View Download 0.246 c.37.1 P-loop containing nucleoside triphosphate hydrolases
View Download 0.241 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.241 a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.233 a.24.11 Bacterial GAP domain
View Download 0.232 a.91.1 Regulator of G-protein signalling, RGS
View Download 0.231 d.55.1 Ribosomal protein L22
View Download 0.228 a.25.1 Ferritin-like
View Download 0.224 c.37.1 P-loop containing nucleoside triphosphate hydrolases
View Download 0.221 c.23.6 Cobalamin (vitamin B12)-binding domain
View Download 0.216 d.15.1 Ubiquitin-like
View Download 0.214 a.118.8 TPR-like
View Download 0.214 d.122.1 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
View Download 0.209 a.24.14 FAT domain of focal adhesion kinase
View Download 0.204 a.118.16 Testis/brain RNA-binding protein (TB-RBP)
View Download 0.203 c.3.1 FAD/NAD(P)-binding domain
View Download 0.201 c.23.6 Cobalamin (vitamin B12)-binding domain

Predicted Domain #3
Region A:
Residues: [288-764]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PYTPLQQMND IRSERTLFFM IGSSNTLLAE QKEELCHIFV NTDNSTVDIL DKTLNPVLQL  60
   61 SSHDKKWIES ISGIVSDTWN ENDDETPKNS QFEGSEDFIR WQFEDYLTGL LSSVKLSDYL 120
  121 DLHKENDQAL KTIPEDMLNS NPVHLFNLNW VQSWKETQNF LIFNSRTDDR LFDLFPPKHI 180
  181 YNGADTLSLL QQRFLATFHN LKRSSSNSSS NKNGHQSEED IKDQESIESK KSVSQISVNP 240
  241 GKNTDKPAAN LWNSWKEYFN KPKNTANEDV TESTEDLKNR SKTSNAIQKA MMGLGLHYKP 300
  301 DAETDQQSEE VGNSEDNEDD DTDEDSEDDD DDGGDDDDSE DDDDDDDGEG DENGDDGEGD 360
  361 ENGDDGEGDE NGDKEDSQDF SNGFTDVTNI NTDHDKENEQ NFEGNAENFN EDETVADKDI 420
  421 EGGPESNKNS DSKTDIYEND RNVEDSSKTR NTVKKSNEEG GANDAAIGNC VQDEEKL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [429-597]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PVHLFNLNWV QSWKETQNFL IFNSRTDDRL FDLFPPKHIY NGADTLSLLQ QRFLATFHNL  60
   61 KRSSSNSSSN KNGHQSEEDI KDQESIESKK SVSQISVNPG KNTDKPAANL WNSWKEYFNK 120
  121 PKNTANEDVT ESTEDLKNRS KTSNAIQKAM MGLGLHYKPD AETDQQSEE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [598-764]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VGNSEDNEDD DTDEDSEDDD DDGGDDDDSE DDDDDDDGEG DENGDDGEGD ENGDDGEGDE  60
   61 NGDKEDSQDF SNGFTDVTNI NTDHDKENEQ NFEGNAENFN EDETVADKDI EGGPESNKNS 120
  121 DSKTDIYEND RNVEDSSKTR NTVKKSNEEG GANDAAIGNC VQDEEKL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle