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View Structure Prediction Details

Protein: AHP1
Organism: Saccharomyces cerevisiae
Length: 176 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AHP1.

Description E-value Query
Range
Subject
Range
gi|17232133, gi|... - gi|17232133|ref|NP_488681.1| peroxiredoxin [Nostoc sp. PCC 7120], gi|17133778|dbj|BAB76340.1| peroxi...
gi|75701970, gi|... - gi|75908245|ref|YP_322541.1| Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen...
gi|25285298 - pir||AI2385 peroxiredoxin [imported] - Nostoc sp. (strain PCC 7120)
9.0E-48 [2..176] [10..167]
gi|6435548, gi|6... - gi|6435548|pdb|1QQ2|B Chain B, Crystal Structure Of A Mammalian 2-Cys Peroxiredoxin, Hbp23, gi|64355...
3.0E-47 [16..175] [6..162]
gi|3603241 - gi|3603241|gb|AAC35744.1| type II peroxiredoxin 1 [Mus musculus]
3.0E-47 [4..175] [7..161]
PRDX2_BOVIN - Peroxiredoxin-2 OS=Bos taurus GN=PRDX2 PE=2 SV=1
3.0E-47 [5..175] [9..162]
PRDX1, PDX1 - peroxiredoxin 1, pancreatic and duodenal homeobox 1
gi|123992995, gi... - gi|61357509|gb|AAX41397.1| peroxiredoxin 1 [synthetic construct], gi|208967016|dbj|BAG73522.1| perox...
gi|114556242, gi... - gi|55586231|ref|XP_513123.1| PREDICTED: peroxiredoxin 1 isoform 6 [Pan troglodytes], gi|114556248|re...
7.0E-47 [4..175] [7..162]

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Predicted Domain #1
Region A:
Residues: [1-176]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDLVNKKFP AGDYKFQYIA ISQSDADSES CKMPQTVEWS KLISENKKVI ITGAPAAFSP  60
   61 TCTVSHIPGY INYLDELVKE KEVDQVIVVT VDNPFANQAW AKSLGVKDTT HIKFASDPGC 120
  121 AFTKSIGFEL AVGDGVYWSG RWAMVVENGI VTYAAKETNP GTDVTVSSVE SVLAHL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 121.770868
Match: 1h4oA_
Description: Peroxiredoxin 5
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
antioxidant activity 3.26520127994042 bayes_pls_golite062009
peroxidase activity 3.04028765378214 bayes_pls_golite062009
oxidoreductase activity, acting on peroxide as acceptor 3.04028765378214 bayes_pls_golite062009
peroxiredoxin activity 2.12777217096121 bayes_pls_golite062009
glutathione peroxidase activity 2.012364779649 bayes_pls_golite062009
selenium binding 1.97951129054219 bayes_pls_golite062009
thioredoxin peroxidase activity 1.96134566495756 bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors 1.8187537496904 bayes_pls_golite062009
disulfide oxidoreductase activity 1.32811008894503 bayes_pls_golite062009
hydrolase activity 1.22195225405134 bayes_pls_golite062009
peptidase activity 0.883522845958727 bayes_pls_golite062009
phospholipid-hydroperoxide glutathione peroxidase activity 0.874146425427531 bayes_pls_golite062009
binding 0.828696005067827 bayes_pls_golite062009
catalytic activity 0.672192331361968 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 0.633952012887619 bayes_pls_golite062009
endopeptidase activity 0.221581298285454 bayes_pls_golite062009
alkyl hydroperoxide reductase activity 0.21601252862268 bayes_pls_golite062009
intramolecular oxidoreductase activity 0.13913802190798 bayes_pls_golite062009
protein binding 0.134341907247724 bayes_pls_golite062009
protein disulfide oxidoreductase activity 0.0719543694089202 bayes_pls_golite062009

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