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View Structure Prediction Details

Protein: XDJ1
Organism: Saccharomyces cerevisiae
Length: 459 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for XDJ1.

Description E-value Query
Range		 Subject
Range
XDJ1 - Putative chaperone, homolog of E. coli DnaJ, closely related to Ydj1p; the authentic, non-tagged pro...
XDJ1_YEAST - DnaJ protein homolog XDJ1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=XDJ1 PE=1 SV=2
 0.0 [1..459] [1..459]
gi|4008159 - gi|4008159|dbj|BAA35121.1| DnaJ homolog [Salix gilgiana]
 0.0 [2..459] [6..420]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 0.0 [2..459] [6..419]
gi|4210948 - gi|4210948|gb|AAD12055.1| DnaJ protein [Hevea brasiliensis]
 0.0 [2..459] [6..415]
gi|10945671, gi|... - gi|10945671|gb|AAG24643.1|AF308738_1 J2P [Daucus carota], gi|10945669|gb|AAG24642.1|AF308737_1 J1P [...
 0.0 [2..459] [6..418]
DNJH2_ALLPO - DnaJ protein homolog 2 OS=Allium porrum GN=LDJ2 PE=2 SV=1
 0.0 [2..459] [6..418]
DNJH_CUCSA - DnaJ protein homolog OS=Cucumis sativus GN=DNAJ1 PE=2 SV=1
 0.0 [2..459] [5..413]
gi|6782421 - gi|6782421|gb|AAF28382.1|AF124139_1 DnaJ-like protein [Lycopersicon esculentum]
 0.0 [2..459] [6..419]
DNAJ_GEOTM - Chaperone protein DnaJ OS=Geobacillus thermoglucosidasius GN=dnaJ PE=3 SV=1
 0.0 [7..416] [3..377]

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Predicted Domain #1
Region A:
Residues: [1-120] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGSDRGDRL YDVLGVTRDA TVQEIKTAYR KLALKHHPDK YVDQDSKEVN EIKFKEITAA  60
   61 YEILSDPEKK SHYDLYGDDN GAASSGGANG FGDEDFMNFF NNFFNNGSHD GNNFPGEYDA 120
  121

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 149.30103
Match: 1bq0__
Description: DnaJ chaperone, N-terminal (J) domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
unfolded protein binding 3.04403163860617 bayes_pls_golite062009
heat shock protein binding 2.17994194200939 bayes_pls_golite062009
binding 2.03854863870179 bayes_pls_golite062009
chaperone binding 1.61155546076854 bayes_pls_golite062009
protein binding 0.912937133925792 bayes_pls_golite062009
Hsp70 protein binding 0.541755903922701 bayes_pls_golite062009
nucleic acid binding 0.423488346839872 bayes_pls_golite062009
transcription regulator activity 0.146399219759372 bayes_pls_golite062009
catalytic activity 0.106988907594358 bayes_pls_golite062009
DNA binding 0.10307408349439 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [121-238] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YEEGNSTSSK DIDIDISLTL KDLYMGKKLK FDLKRQVICI KCHGSGWKPK RKIHVTHDVE  60
   61 CESCAGKGSK ERLKRFGPGL VASQWVVCEK CNGKGKYTKR PKNPKNFCPD CAGLGLLS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.69897
Match: 1exkA_
Description: Cysteine-rich domain of the chaperone protein DnaJ.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.13705208493215 bayes_pls_golite062009
unfolded protein binding 2.04158808514315 bayes_pls_golite062009
protein binding 0.882827615657312 bayes_pls_golite062009
protein disulfide isomerase activity 0.290861970307477 bayes_pls_golite062009
intramolecular oxidoreductase activity, transposing S-S bonds 0.290861970307477 bayes_pls_golite062009
catalytic activity 0.276917867171685 bayes_pls_golite062009
intramolecular oxidoreductase activity, interconverting keto- and enol-groups 0.0964866497718595 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [239-399] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KKEIITVNVA PGHHFNDVIT VKGMADEEID KTTCGDLKFH LTEKQENLEQ KQIFLKNFDD  60
   61 GAGEDLYTSI TISLSEALTG FEKFLTKTFD DRLLTLSVKP GRVVRPGDTI KIANEGWPIL 120
  121 DNPHGRCGDL YVFVHIEFPP DNWFNEKSEL LAIKTNLPSS S

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 73.0
Match: 1c3gA_
Description: Heat shock protein 40 Sis1
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [400-459] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SCASHATVNT EDDSNLTNNE TISNFRIIHT DDLPEGIRPF KPEAQDSAHQ KARSSYCCIQ  60
   61

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle