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View Structure Prediction Details

Protein: FMP25
Organism: Saccharomyces cerevisiae
Length: 583 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FMP25.

Description E-value Query
Range
Subject
Range
FMP25_YEAST - Protein FMP25, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FMP25 PE=4 ...
FMP25 - Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purifi...
0.0 [1..583] [1..583]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
6.0E-95 [3..512] [3876..4322]
HERC3 - hect domain and RLD 3
gi|7657152 - ref|NP_055421.1| hect domain and RLD 3 [Homo sapiens]
gi|187252515, gi... - gi|187252515|gb|AAI66672.1| Hect domain and RLD 3 [synthetic construct], gi|168274306|dbj|BAG09573.1...
8.0E-73 [161..572] [5..385]
gi|12856817 - gi|12856817|dbj|BAB30794.1| unnamed protein product [Mus musculus]
8.0E-72 [161..567] [5..380]
UVR8_ARATH - Ultraviolet-B receptor UVR8 OS=Arabidopsis thaliana GN=UVR8 PE=1 SV=1
1.0E-70 [191..576] [17..355]

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Predicted Domain #1
Region A:
Residues: [1-158]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFRLFTRTS QRLPRLNWVS PIRRYAKQPQ YDEAELFAEN INHGAYKAKK RPSDEHFQWP  60
   61 EKSPDQITKE SELQWERMAK LSAVGQGILI LVVVGGLGTA YLRWPELKSW WLIKMNGGRI 120
  121 NATQEQSGQD SLEKLIRQKA KNLLREIPQV PAFQLGID

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [159-583]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HPGVYIWGRC HSKDSLFPVR VPNLDGRKFR DILLAPSDDF NTNFAIDEKG DLISWDDLGQ  60
   61 TKTILPDQDL TSMKYSSHFL YALNKKGEIL VIPIRTPDLI ASQVSSRRSK LLPWKTKLRY 120
  121 DWKLQTNQIF NGKEGEKRVV QFDAGSHHLV LLSNLGKAYC CATGNDQKQA QVSKGQFGIP 180
  181 TFSQFDEFPP NNQLFEIELL NKFKHEGEDV VRKREIKKIA CGSYHTLAID KTGEIYAFGW 240
  241 NRFGQLALPI SYNLEYVSFP RSVTHAFKPH FPGMTNWKCV DIHCDDETSF VTIRKPGSTS 300
  301 DHHYFAFGNG LFGELGNNTF KNSQCDPIKI KSDDKKLTNW SCGSHCVFTE TEQENEVIAW 360
  361 GNNDHGQLGI GKKTMKCAKP MNIPEVLKPG QDTTDLDSIY NSKLHLKKEQ RVVTNGNKSC 420
  421 LYWRV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 101.0
Match: 1a12A_
Description: Regulator of chromosome condensation RCC1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.139824392251248 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle